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COVID-19 UPDATES

International variation in the management of severe COVID-19 patients
Elie Azoulay, Jan de Waele, Ricard Ferrer, et al.
Critical Care 2020 24:486
Research
Published on: 5 August 2020

Serum levels of receptor-interacting protein kinase-3 in patients with COVID-19
Hideta Nakamura, Takeshi Kinjo, Wakako Arakaki, et al.
Critical Care 2020 24:484
Research Letter
Published on: 4 August 2020

Plasma exchange in critically ill COVID-19 patients
Christian Morath, Markus A. Weigand, Martin Zeier, et al.
Critical Care 2020 24:481
Research Letter
Published on: 4 August 2020

Development of a work of breathing scale and monitoring need of intubation in COVID-19 pneumonia
Mylene Apigo, Jeffrey Schechtman, Nyembezi Dhliwayo, et al. 
Critical Care 2020 24:477
Research Letter
Published on: 31 July 2020

ACEI/ARB therapy in COVID-19: the double-edged sword of ACE2 and SARS-CoV-2 viral docking
Chidinma L. Onweni, Yu Shrike Zhang, Thomas Caulfield, et al.
Critical Care 2020 24:475
Research Letter
31 July 2020

Efficacy of convalescent plasma for the treatment of severe influenza
Zhiheng Xu, Jianmeng Zhou, Yongbo Huang, et al.
Critical Care 2020 24:469
Research
Published on: 29 July 2020

Cardiac injury associated with severe disease or ICU admission and death in hospitalized patients with COVID-19: a meta-analysis and systematic review
Xinye Li, Xiandu Pan, Yanda Li, et al.
Critical Care 2020 24:468
Research
Published on: 28 July 2020

Pooled prevalence of deep vein thrombosis among coronavirus disease 2019 patients
Ying Wang, Li Shi, Haiyan Yang, et al.
Critical Care 2020 24:466
Research Letter
Published on: 28 July 2020

Age, sex, and comorbidities predict ICU admission or mortality in cases with SARS-CoV2 infection: a population-based cohort study
Filipe S. Cardoso, Ana L. Papoila, Rita Sá Machado and Pedro Fidalgo
Critical Care 2020 24:465
Research Letter
Published on: 28 July 2020

Incidence and mortality of pulmonary embolism in COVID-19: a systematic review and meta-analysis
Shu-Chen Liao, Shih-Chieh Shao, Yih-Ting Chen, et al.
Critical Care 2020 24:464
Research Letter
Published on: 27 July 2020

Provision of ECPR during COVID-19: evidence, equity, and ethical dilemmas
Elliott Worku, Denzil Gill, Daniel Brodie, et al.
Critical Care 2020 24:462
Viewpoint
Published on: 27 July 2020

Lactate dehydrogenase elevations is associated with severity of COVID-19: a meta-analysis
Xiao-Yun Chen, Ming-Yao Huang, Zheng-wei Xiao, et al.
Critical Care 2020 24:459
Research Letter
Published on: 24 July 2020

Could the severity of COVID-19 be increased by low gastric acidity?
Elizabeth Price
Critical Care 2020 24:456
Research Letter
Published on: 22 July 2020

Nebulised heparin as a treatment for COVID-19: scientific rationale and a call for randomised evidence
Frank M. P. van Haren, Clive Page, John G. et al.
Critical Care 2020 24:454
Review
Published on: 22 July 2020

Plasma levels of soluble ACE2are associated with sex, Metabolic Syndrome, and its biomarkers in a large cohort, pointing to a possible mechanism for increased severity in COVID-19
Sergey A. Kornilov, Isabelle Lucas, et al.
Critical Care 2020 24:452
Research Letter
Published on: 22 July 2020

Chinese herbal experience for the 2019 novel coronavirus
Ronglin Jiang, Kungen Wang, Wei Mao, et al.
Critical Care 2020 24:451
Research Letter
Published on: 21 July 2020

Convalescent plasma to treat critically ill patients with COVID-19: framing the need for randomised clinical trials
Manu Shankar-Hari, Lise Estcourt, Heli Harvala, et al.
Critical Care 2020 24:449
Editorial
Published on: 20 July 2020

Detection of IgG antibody during the follow-up in patients with COVID-19 infection
Jiao Liu, Jun Guo, Qianghong Xu, et al.
Critical Care 2020 24:448
Research Letter
Published on: 20 July 2020

Nutrition of the COVID-19 patient in the intensive care unit (ICU): a practical guidance
Ronan Thibault, Philippe Seguin, Fabienne Tamion,  et al.
Critical Care 2020 24:447
Review
Published on: 19 July 2020

Neuromuscular blocking agents (NMBA) for COVID-19 acute respiratory distress syndrome: a multicenter observational study
Romain Courcelle, Stéphane Gaudry, Nicolas Serck, et al. 
Critical Care 2020 24:446
Research Letter
Published on: 19 July 2020

Blocking IL-1 to prevent respiratory failure in COVID-19
Frank L. van de Veerdonk and Mihai G. Netea
Critical Care 2020 24:445
Review
Published on: 18 July 2020

Infliximab against severe COVID-19-induced cytokine storm syndrome with organ failure—a cautionary case series
Andreas Stallmach, Andreas Kortgen, Falk Gonnert, et al.
Critical Care 2020 24:444
Research Letter
Published on: 17 July 2020

The application of 6S and PDCA management strategies in the nursing of COVID-19 patients
Wenju Wei, Sicong Wang, Hongliang Wang and Hongjia Quan
Critical Care 2020 24:443
Editorial
Published on: 16 July 2020

Mortality rate of acute kidney injury in SARS, MERS, and COVID-19 infection: a systematic review and meta-analysis
Yih-Ting Chen, Shih-Chieh Shao, Edward Chia-Cheng Lai, et al.
Critical Care 2020 24:439
Research Letter
Published on: 16 July 2020

Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study
Shuai Zhang, Mengfei Guo, Limin Duan, et al.
Critical Care 2020 24:438
Research
Published on: 16 July 2020

Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation
Marina Rieder, Tobias Wengenmayer, Dawid Staudacher, et al.
Critical Care 2020 24:435
Research Letter
Published on: 14 July 2020

Nurse-performed ultrasound: a new weapon against COVID-19
Jianhua Sun, Qi Li, Xinjuan Wu, Xiaoting Wang and Dawei Liu
Critical Care 2020 24:430
Letter
Published on: 14 July 2020

Atorvastatin associated with decreased hazard for death in COVID-19 patients admitted to an ICU: a retrospective cohort study
Guillermo Rodriguez-Nava, Daniela Patricia Trelles-Garcia, Maria Adriana Yanez-Bello, et al.
Critical Care 2020 24:429
Research Letter
Published on: 14 July 2020

Prone positioning under VV-ECMO in SARS-CoV-2-induced acute respiratory distress syndrome
Bruno Garcia, Nicolas Cousin, Claire Bourel, et al.
Critical Care 2020 24:428
Research Letter
Published on: 14 July 2020

Walkie talkies to aid health care workers’ compliance with personal protective equipment in the fight against COVID-19
Dominic Fenn, Jonny Coppel, Jessica Kearney, et al.
Critical Care 2020 24:424
Letter
Published on: 13 July 2020

Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19
Wentao Ni, Xiuwen Yang, Deqing Yang, et al.
Critical Care 2020 24:422
Review
Published on: 13 July 2020

Neurological manifestations of COVID-19: a systematic review
Gaurav Nepal, Jessica Holly Rehrig, Gentle Sunder Shrestha, et al.
Critical Care 2020 24:421
Research
Published on: 13 July 2020

Administration of umbilical cord mesenchymal stem cells in patients with severe COVID-19 pneumonia
Zhinian Guo, Yunlong Chen, Xiaoyu Luo, et al.
Critical Care 2020 24:420
Research Letter
Published on: 11 July 2020

COVID-19-associated acute cerebral venous thrombosis: clinical, CT, MRI and EEG features
Fabian Roy-Gash, De Mesmay Marine, Devys Jean-Michel, et al.
Critical Care 2020 24:419
Research Letter
Published on: 11 July 2020

Comparison of hydroxychloroquine, lopinavir/ritonavir, and standard of care in critically ill patients with SARS-CoV-2 pneumonia: an opportunistic retrospective analysis
Marie Lecronier, Alexandra Beurton, Sonia Burrel, et al.
Critical Care 2020 24:418
Research
Published on: 11 July 2020

Effect of favipiravir and an anti-inflammatory strategy for COVID-19
Hitoshi Yamamura, Hiroshi Matsuura, Junichiro Nakagawa, et al.
Critical Care 2020 24:413
Research Letter
Published on: 9 July 2020

Impact of initial respiratory compliance in ventilated patients with acute respiratory distress syndrome related to COVID-19
Florent Laverdure, Amélie Delaporte, Astrid Bouteau, et al.
Critical Care 2020 24:412
Research Letter
Published on: 9 July 2020

Adrenomedullin in COVID-19 induced endotheliitis
Darius Cameron Wilson, Joerg C. Schefold, Jaume Baldirà, et al.
Critical Care 2020 24:411
Letter
Published on: 9 July 2020

Co-infections in COVID-19 critically ill and antibiotic management: a prospective cohort analysis
Alexia Verroken, Anaïs Scohy, Ludovic Gérard, et al.
Critical Care 2020 24:410
Research Letter
Published on: 9 July 2020

Angiotensin II treatment in COVID-19 patients: more risk than benefit? A single-center experience
Ulrike Heinicke, Elisabeth Adam, Michael Sonntagbauer, et al. 
Critical Care 2020 24:409
Research Letter
Published on: 9 July 2020

Transpulmonary pressure in SARS-CoV-2-associated acute respiratory distress syndrome: a single-center observational study
Severin Ramin, Jonathan Charbit, Geoffrey Dagod, et al.
Critical Care 2020 24:408
Research Letter
Published on: 9 July 2020

Unrecognized diabetes in critically ill COVID-19 patients
Sebastian J. Klein, Dietmar Fries, Susanne Kaser, et al.
Critical Care 2020 24:406
Research Letter
Published on: 9 July 2020

Molecular mechanisms of sex bias differences in COVID-19 mortality
Yuchong Li, Mirjana Jerkic, Arthur S. Slutsky and Haibo Zhang
Critical Care 2020 24:405
Viewpoint
Published on: 9 July 2020

Double trouble: methanol outbreak in the wake of the COVID-19 pandemic in Iran—a cross-sectional assessment
Hossein Hassanian-Moghaddam, Nasim Zamani, Ali-Asghar Kolahi, Rebecca McDonald and Knut Erik Hovda
Critical Care 2020 24:402
Research Letter
Published on: 9 July 2020

Is delirium a specific complication of viral acute respiratory distress syndrome?
Markus Jäckel, Xavier Bemtgen, Tobias Wengenmayer, et al.
Critical Care 2020 24:401
Research Letter
Published on: 9 July 2020

Visualisation of epidemiological map using an Internet of Things infectious disease surveillance platform
Guanghao Sun, Nguyen Vu Trung, Le Thi Hoi, et al.
Critical Care 2020 24:400
Research Letter
Published on: 9 July 2020

Classification of COVID-19 in intensive care patients
Xiaofan Lu, Yang Wang, Taige Chen, Jun Wang and Fangrong Yan
Critical Care 2020 24:399
Research Letter

COVID-19: a hypothesis regarding the ventilation-perfusion mismatch
Mario G. Santamarina, Dominique Boisier, Roberto Contreras, et al.
Critical Care 2020 24:395
Editorial
Published on: 6 July 2020

Clinical course and predictors of 60-day mortality in 239 critically ill patients with COVID-19: a multicenter retrospective study from Wuhan, China
Jiqian Xu, Xiaobo Yang, Luyu Yang, et al.
Critical Care 2020 24:394
Research
Published on: 6 July 2020

Nafamostat mesylate treatment in combination with favipiravir for patients critically ill with Covid-19: a case series
Kent Doi, Mahoko Ikeda, Naoki Hayase, et al.
Critical Care 2020 24:392
Research Letter
Published on: 3 July 2020

Virtual reality device training for extracorporeal membrane oxygenation
Georg Wolff, Raphael R. Bruno, Martina Reiter, et al. 
Critical Care 2020 24:390
Letter
Published on: 2 July 2020

Acute complications and mortality in hospitalized patients with coronavirus disease 2019: a systematic review and meta-analysis
Nicola Potere, Emanuele Valeriani, Matteo Candeloro, et al
Critical Care 2020 24:389
Research
Published on: 2 July 2020

Hospital preparedness for mass critical care during SARS-CoV-2 pandemic
Thomas Wurmb, Katja Scholtes, Felix Kolibay, et al. 
Critical Care 2020 24:386
Viewpoint
Published on: 30 June 2020

Italian pulmonologist units and COVID-19 outbreak: “mind the gap”!
Raffaele Scala, Teresa Renda, Antonio Corrado and Adriano Vaghi
Critical Care 2020 24:381
Letter
Published on: 29 June 2020

Mobilization practices in critically ill children: a European point prevalence study (EU PARK-PICU)
Erwin Ista, Barnaby R. Scholefield, Joseph C. Manning, et al.
Critical Care 2020 24:368
Research
Published on: 24 June 2020

VEGF-D: a novel biomarker for detection of COVID-19 progression
Yaxian Kong, Junyan Han, Xueying Wu, et al.
Critical Care 2020 24:373
Research Letter
Published on: 23 June 2020

Screening for low testosterone is needed for early identification and treatment of men at high risk of mortality from Covid-19
Simon Peter Rowland and Elizabeth O’Brien Bergin
Critical Care 2020 24:367
Letter
Published on: 19 June 2020

“War to the knife” against thromboinflammation to protect endothelial function of COVID-19 patients
Gabriele Guglielmetti, Marco Quaglia, Pier Paolo Sainaghi, et al.
Critical Care 2020 24:365
Viewpoint
Published on: 19 June 2020

Prevention of thrombotic risk in hospitalized patients with COVID-19 and hemostasis monitoring
Sophie Susen, Charles Ambroise Tacquard, Alexandre Godon, et al.
Critical Care 2020 24:364
Review
Published on: 19 June 2020

Bedside rapid placement of nasointestinal feeding tube via ultrasound-guided stylet positioning in critical COVID-19 patients
Chuan-xi Chen, Zheng-deng Wei, Yong-jun Liu, et al.
Critical Care 2020 24:361
Research Letter
Published on: 18 June 2020 

The unique characteristics of COVID-19 coagulopathy
Toshiaki Iba, Jerrold H. Levy, Jean Marie Connors, et al.
Critical Care 2020 24:360
Review
Published on: 18 June 2020

Compassionate use of others’ immunity — understanding gut microbiome in Covid-19
Prashanth Thalanayar Muthukrishnan and Robert Faillace
Critical Care 2020 24:358
Letter
Published on: 18 June 2020

Single ventilator for multiple patients during COVID19 surge: matching and balancing patients
Lonnie G. Petersen, James Friend and Sidney Merritt
Critical Care 2020 24:357
Research Letter
Published on: 18 June 2020

Prevalence and impact of acute renal impairment on COVID-19: a systematic review and meta-analysis
Xianghong Yang, Yiyang Jin, Ranran Li, Zhongheng Zhang, et al. 
Critical Care 2020 24:356
Research
Published on: 18 June 2020

The vascular endothelium: the cornerstone of organ dysfunction in severe SARS-CoV-2 infection
Stéphanie Pons, Sofiane Fodil, Elie Azoulay and Lara Zafrani
Critical Care 2020 24:353
Review
Published on: 16 June 2020

The ARDSnet protocol may be detrimental in COVID-19
Vasiliki Tsolaki, George E. Zakynthinos and Dimosthenis Makris
Critical Care 2020 24:351
Letter
Published on: 16 June 2020

Paediatric and adult critical care medicine: joining forces against Covid-19
Martin C. J. Kneyber, Bernadette Engels and Peter H. J. van der Voort
Critical Care 2020 24:350
Letter
Published on: 16 June 2020

Micronutrient status of COVID-19 patients: a critical consideration
Anitra C. Carr
Critical Care 2020 24:349
Letter
Published on: 16 June 2020

Invasive mechanical ventilation in COVID-19 patient management: the experience with 469 patients in Wuhan
Jing Hua, Chenchen Qian, Zhibing Luo, et al.
Critical Care 2020 24:348
Research Letter
Published on: 16 June 2020

Incidence of acute kidney injury in COVID-19 infection: a systematic review and meta-analysis
Yih-Ting Chen, Shih-Chieh Shao, Cheng-Kai Hsu, et al.
Critical Care 2020 24:346
Research Letter
Published on: 16 June 2020

Early rehabilitation with dedicated use of belt-type electrical muscle stimulation for severe COVID-19 patients
Kensuke Nakamura, Hidehiko Nakano, Hiromu Naraba, et al.
Critical Care 2020 24:342
Letter
Published on: 15 June 2020

Clinical features and outcomes of COVID-19 patients with gastrointestinal symptoms
Chao Cao, Meiping Chen, Li He, et al.
Critical Care 2020 24:340
Research Letter
Published on: 15 June 2020

COVID-19 targets the right lung
Jingwen Li, Xiaxia Yu, Shaoping Hu, Zhicheng Lin, Nian Xiong and Yi Gao
Critical Care 2020 24:339
Research Letter
Published on: 15 June 2020

Infection prevention and control in nursing severe coronavirus disease (COVID-19) patients during the pandemic
Lei Ye, Shulan Yang and Caixia Liu
Critical Care 2020 24:338
Editorial
Published on: 12 June 2020

A plea for avoiding systematic intubation in severely hypoxemic patients with COVID-19-associated respiratory failure
Eduardo Villarreal-Fernandez, Ravi Patel, Reshma Golamari, et al.
Critical Care 2020 24:337
Research Letter
Published on: 12 June 2020

Interferon beta-1a for COVID-19: critical importance of the administration route
Juho Jalkanen, Maija Hollmén and Sirpa Jalkanen
Critical Care 2020 24:335
Commentary
Published on: 12 June 2020

A valuable and affordable handheld ultrasound in combating COVID-19
Feng Qian, Xueqin Zhou, Jianqiao Zhou, et al.
Citation:Critical Care 2020 24:334
Research Letter
Published on: 12 June 2020

Non-invasive ventilation in the treatment of early hypoxemic respiratory failure caused by COVID-19: considering nasal CPAP as the first choice
Lili Guan, Luqian Zhou, Jehane Michael Le Grange, et al. 
Critical Care 2020 24:333
Letter

COVID-19: opening a new paradigm in thromboprophylaxis for critically ill patients?
Raquel Ferrandis, Juan V. Llau, Manuel Quintana, et al.
Critical Care 2020 24:332
Letter
Published on: 11 June 2020

Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients
Irma Convertino, Marco Tuccori, Sara Ferraro, et al.
Critical Care 2020 24:331
Viewpoint
Published on: 11 June 2020

Ventilator management in the age of COVID-19: response to “Logistic and organizational aspects of a dedicated intensive care unit for COVID-19 patients”
Alastair E. Moody, Bryce D. Beutler, Daniel Antwi-Amoabeng, et al.
Critical Care 2020 24:329
Letter

Intra-hospital preventive principles to protect frontline healthcare workers to overcome pandemic COVID-19 in Taiwan
Ting-Wan Tan, Chih-Ming Chang and Man-Na Chang
Critical Care 2020 24:328
Editorial
Published on: 11 June 2020

Low molecular weight heparins in COVID-19 patients: beware of augmented renal clearance!
Teresa Maria Tomasa-Irriguible, Sergi Martínez-Vega, Ester Mor-Marco, et al.
Critical Care 2020 24:325
Research Letter
Published on: 10 June 2020

Should we deny ICU admission to the elderly? Ethical considerations in times of COVID-19
Lenneke E. M. Haas, Dylan W. de Lange, Diederik van Dijk and Johannes J. M. van Delden
Critical Care 2020 24:321
Commentary
Published on: 9 June 2020

Systemic hypoferremia and severity of hypoxemic respiratory failure in COVID-19
Akshay Shah, Joe N. Frost, Louise Aaron, Killian Donovan and Hal Drakesmith
Critical Care 2020 24:320
Research Letter
Published on: 9 June 2020

A simple custom appliance against droplet and aerosol transmission of COVID-19 during advanced airway management
Meng Chi, Changming Lou, Xiuli Zhao, Xin Sui and Fei Han
Critical Care 2020 24:319
Research Letter
Published on: 8 June 2020

Blocking mineralocorticoid receptor with spironolactone may have a wide range of therapeutic actions in severe COVID-19 disease
Lucas Liaudet and Csaba Szabo
Critical Care 2020 24:318
Letter
Published on: 8 June 2020

Extracorporeal membrane oxygenation programs for COVID-19 in China
Chenglong Li, Xiaotong Hou, Zhaohui Tong, et al.
Critical Care 2020 24:317
Research Letter
Published on: 8 June 2020

Three-step checklist for tracheostomy in critically ill COVID-19 patients
Maria Vargas and Giuseppe Servillo
Critical Care 2020 24:316
Research Letter
Published on: 8 June 2020

Non-febrile COVID-19 patients were common and often became critically ill: a retrospective multicenter cohort study
Yichen Li, Na Jiao, Lixin Zhu, et al.
Critical Care 2020 24:314
Research Letter
Published on: 8 June 2020

Prehospital pulse oximetry: a red flag for early detection of silent hypoxemia in COVID-19 patients
Romain Jouffroy, Daniel Jost and Bertrand Prunet
Critical Care 2020 24:313
Research Letter

Neutrophil Elastase Inhibitors: A potential prophylactic treatment option for SARS-CoV-2-induced respiratory complications?
Mahmoud M. A. Mohamed, Ismail Amr El-Shimy and Muhammad Abdul Hadi
Critical Care 2020 24:311
Editorial
Published on: 8 June 2020

Critical care physicians treating COVID-19: mind the nervous system!
Julian Bösel
Critical Care 2020 24:310
Letter
Published on: 8 June 2020

Peritoneal dialysis for COVID-19-associated acute kidney injury
Mika Nagatomo, Hiroyuki Yamada, Ken Shinozuka, et al.
Critical Care 2020 24:309
Research Letter
Published on: 8 June 2020

Team management in critical care units for patients with COVID-19: an experience from Hunan Province, China
Li Tang, Xian-Mei Zhao and Xiao-Yan Yu
Critical Care 2020 24:304
Editorial
Published on: 6 June 2020

PEEP levels in COVID-19 pneumonia
Vasiliki Tsolaki, Ilias Siempos, Eleni Magira, et al.
Critical Care 2020 24:303
Research Letter
Published on: 6 June 2020

ECMO use in COVID-19: lessons from past respiratory virus outbreaks—a narrative review
Hwa Jin Cho, Silver Heinsar, In Seok Jeong, et al.
Critical Care 2020 24:301
Review
Published on: 6 June 2020

Lung ventilation function characteristics of survivors from severe COVID-19: a prospective study
Xianyong Li, Changsong Wang, Shengjie Kou, 
Critical Care 2020 24:300
Research Letter
Published on: 6 June 2020

Clinical characteristics of invasive pulmonary aspergillosis in patients with COVID-19 in Zhejiang, China: a retrospective case series
Jie Wang, Qing Yang, Piaopiao Zhang, et al.
Critical Care 2020 24:299
Research Letter
Published on: 5 June 2020

Body temperature correlates with mortality in COVID-19 patients
Serena Tharakan, Koichi Nomoto, Satoshi Miyashita and Kiyotake Ishikawa
Critical Care 2020 24:298
Research Letter
Published on: 5 June 2020

How COVID-19 pandemic changed our communication with families: losing nonverbal cues
Annachiara Marra, Pasquale Buonanno, Maria Vargas, et al.
Critical Care 2020 24:297
Editorial
Published on: 5 June 2020

Angiotensin II administration to COVID-19 patients is not advisable
Robert C. Speth
Citation:Critical Care 2020 24:296
Commentary
Published on: 5 June 2020

COVID-19—immunity from prosecution for physicians forced to allocate scarce resources: the Italian perspective
Marco Ricci and Pasquale Gallina
Critical Care 2020 24:295
Letter
Published on: 5 June 2020

Admission decisions to intensive care units in the context of the major COVID-19 outbreak: local guidance from the COVID-19 Paris-region area
Élie Azoulay, Sadek Beloucif, Bertrand Guidet, et al.
Critical Care 2020 24:293
Viewpoint

In-hospital airway management of COVID-19 patients
Elise H. Sullivan, Lauren E. Gibson, Lorenzo Berra, et al.
Critical Care 2020 24:292
Review
Published on: 5 June 2020

Elevation of plasma angiotensin II level is a potential pathogenesis for the critically ill COVID-19 patients
Zhiyong Wu, Rui Hu, Cuizhen Zhang, et al.
Critical Care 2020 24:290
Research Letter
Published on: 5 June 2020

The challenge of ventilator-associated pneumonia diagnosis in COVID-19 patients
Bruno François, Pierre-François Laterre, Charles-Edouard Luyt and Jean Chastre
Critical Care 2020 24:289
Editorial
Published on: 5 June 2020

Neutrophil-to-lymphocyte ratio as a predictive biomarker for moderate-severe ARDS in severe COVID-19 patients
Aijia Ma, Jiangli Cheng, Jing Yang, et al.
Critical Care 2020 24:288
Research Letter
Published on: 5 June 2020

Mortality rates of patients with COVID-19 in the intensive care unit: a systematic review of the emerging literature
Pipetius Quah, Andrew Li and Jason Phua
Critical Care 2020 24:282
Letter 
Published on: 4 June 2020

Precision medicine for COVID-19: a call for better clinical trials
Gentle Sunder Shrestha, Hem Raj Paneru and Jean-Louis Vincent
Critical Care 2020 24:282
Editorial
Published on: 2 June 2020

Cyclosporine A: a valid candidate to treat COVID-19 patients with acute respiratory failure?
Martin Cour, Michel Ovize and Laurent Argaud
Critical Care 2020 24:276
Editorial
Published on: 2 June 2020

Thrombotic and hemorrhagic events in critically ill COVID-19 patients: a French monocenter retrospective study
Megan Fraissé, Elsa Logre, Olivier Pajot, et al.
Critical Care 2020 24:275
Research Letter
Published on: 2 June 2020

Severe pulmonary embolism in COVID-19 patients: a call for increased awareness
Guillaume Hékimian, Guillaume Lebreton, Nicolas Bréchot, et al.
Critical Care 2020 24:274
Research Letter
Published on: 2 June 2020

Recommendations for the use of vascular access in the COVID-19 patients: an Italian perspective
Mauro Pittiruti and Fulvio Pinelli
Critical Care 2020 24:269
Commentary
Published on: 29 May 2020

Description of an alternative method for optimal and comfortable two-handed face mask ventilation: the transverse mandibular technique
Francois Lemay and Jeremy Cooper
Critical Care 2020 24:267
Letter
Published on: 26 May 2020

How machine learning could be used in clinical practice during an epidemic
Charles Verdonk, Franck Verdonk and Gérard Dreyfus
Critical Care 2020 24:265
Editorial
Published on: 26 May 2020

Universal mobile protection system for aerosol-generating medical interventions in COVID-19 patients
Florian Straube, Clemens Wendtner and Ellen Hoffmann
Critical Care 2020 24:264
Letter
Published on: 26 May 2020

COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients
Matthijs Kox, Tim Frenzel, Jeroen Schouten, et al.
Critical Care 2020 24:263
Research Letter
Published on: 26 May 2020

The importance of a “socially responsible” approach during COVID-19: the invisible heroes of science in Italy
Filippo Sanfilippo, Elena Bignami, Ferdinando Luca Lorini and Marinella Astuto
Critical Care 2020 24:261
Letter
26 May 2020

Essential ICU drug shortages for COVID-19: what can frontline clinicians do?
Wen Ting Siow, Simeon H. Tang, Rohit Vijay Agrawal, et al.
Critical Care 2020 24:260
Letter
Published on: 26 May 2020

Two consecutive myocardial tissue insults for inpatients with COVID-19
Minghua Su, Jieru Peng, Mengjun Wu, et al.
Critical Care 2020 24:259
Research Letter
Published on: 26 May 2020

Prone ventilation of critically ill adults with COVID-19: how to perform CPR in cardiac arrest?
Wioletta Mędrzycka-Dąbrowska, Katarzyna Lewandowska, Daniel Ślęzak and Sebastian Dąbrowski
Citation:Critical Care 2020 24:258
Letter
Published on: 26 May 2020

Clinical analysis of sinus bradycardia in patients with severe COVID-19 pneumonia
Lijuan Hu, Linjing Gong, Zhilong Jiang, et al.
Critical Care 2020 24:257
Research Letter
Published on: 26 May 2020

Prone positioning combined with high-flow nasal or conventional oxygen therapy in severe Covid-19 patients
Cyrielle Despres, Yannick Brunin, Francis Berthier, et al.
Critical Care 2020 24:256
Research Letter
Published on: 26 May 2020

The association of low serum albumin level with severe COVID-19: a systematic review and meta-analysis
Muhammad Aziz, Rawish Fatima, Wade Lee-Smith and Ragheb Assaly
Critical Care 2020 24:255
Research Letter
Published on: 26 May 2020

Early awake prone position combined with high-flow nasal oxygen therapy in severe COVID-19: a case series
Qiancheng Xu, Tao Wang, Xuemei Qin, Yanli Jie, Lei Zha and Weihua Lu
Critical Care 2020 24:250
Research Letter
Published on: 24 May 2020

Effect of flow and cannula size on generated pressure during nasal high flow
Maximilian Pinkham and Stanislav Tatkov
Research Letter
Critical Care 2020 24:248
Published on: 24 May 2020 

Duration of SARS-CoV-2 viral RNA in asymptomatic carriers
Xiquan Yan, Xiaotong Han, Yong Fan, Zhixiong Fang, Da Long and Yimin Zhu
Critical Care 2020 24:245
Research Letter
Published on: 24 May 2020

Adjuvant corticosteroid therapy for critically ill patients with COVID-19
Xiaofan Lu, Taige Chen, Yang Wang, Jun Wang and Fangrong Yan
Critical Care 2020 24:241
Research Letter
Published on: 19 May 2020 

Crucial role of temporary airborne infection isolation rooms in an intensive care unit: containing the COVID-19 outbreak in South Korea
Shin Yup Lee, Sun Ha Choi, Ji Eun Park, et al.
Critical Care 2020 24:238
Research Letter
Published on: 18 May 2020

Logistic and organizational aspects of a dedicated intensive care unit for COVID-19 patients
Maria Vargas, Giuseppe De Marco, Stefania De Simone and Giuseppe Servillo
Critical Care 2020 24:237
Research Letter
Published on: 18 May 2020 

Cardiovascular phenotypes in ventilated patients with COVID-19 acute respiratory distress syndrome
Bruno Evrard, Marine Goudelin, Noelie Montmagnon, Anne-Laure Fedou, Thomas Lafon and Philippe Vignon
Critical Care 2020 24:236
Research Letter
Published on: 18 May 2020 

With the current COVID pandemic: should we use single-use flexible bronchoscopes instead of conventional bronchoscopes?
Patrick M. Honore, Aude Mugisha, Luc Kugener, et al.
Critical Care 2020 24:234
Letter
Published on: 18 May 2020 

Unconventional approaches to mechanical ventilation—step-by-step through the COVID-19 crisis
Christopher Lotz, Quirin Notz, Peter Kranke, Markus Kredel and Patrick Meybohm
Critical Care 2020 24:233
Editorial
Published on: 18 May 2020

Advanced respiratory monitoring in COVID-19 patients: use less PEEP!
Lisanne Roesthuis, Maarten van den Berg and Hans van der Hoeven
Critical Care 2020 24:230
Research Letter
Published on: 15 May 2020

COVID-19: room for treating T cell exhaustion?
Giovanni Riva, Vincenzo Nasillo, Enrico Tagliafico, Tommaso Trenti and Mario Luppi
Critical Care 2020 24:229
Letter
Published on: 15 May 2020

COVID-19 mortality and ICU admission: the Italian experience
Paolo Immovilli, Nicola Morelli, Elio Antonucci, et al.
Critical Care 2020 24:228
Letter
Published on: 15 May 2020

Angiotensin II infusion in COVID-19-associated vasodilatory shock: a case series
Alberto Zangrillo, Giovanni Landoni, Luigi Beretta, et al.
Critical Care 2020 24:227
Research Letter
Published on: 15 May 2020

Safe doubling of ventilator capacity: a last resort proposal for last resorts
J. Geoffrey Chase, Yeong Shiong Chiew, Bernard Lambermont, et al.
Critical Care 2020 24:222
Research Letter
Published on: 14 May 2020

Age and sex differences in soluble ACE2 may give insights for COVID-19
Per Swärd, Andreas Edsfeldt, Anton Reepalu, et al.
Critical Care 2020 24:221
Research Letter
Published on: 14 May 2020

Patients with COVID-19 in 19 ICUs in Wuhan, China: a cross-sectional study
Yuan Yu, Dan Xu, Shouzhi Fu, Jun Zhang, et al.
Critical Care 2020 24:219
Research
Published on: 14 May 2020

Preparing your intensive care unit for the COVID-19 pandemic: practical considerations and strategies
Ken Junyang Goh, Jolin Wong, Jong-Chie Claudia Tien, et al.
Critical Care 2020 24:215
Review
Published on: 11 May 2020

Simultaneous ventilation of two simulated ARDS patients in COVID-19 pandemic
Danny Epstein, Yoav Hoffman, George Dahoud, et al.
Critical Care 2020 24:214
Research Letter
Published on: 11 May 2020

Students Supporting Critical Care – A contention plan to prevent the decompensation of ICUs in the COVID-19 pandemic:Translating Bjorn Ibsens’ polio-lessons to modern times
Pedro David Wendel Garcia, Paola Massarotto, et al.
Critical Care 2020 24:211
Letter
Published on: 8 May 2020

Chloroquine for COVID-19: rationale, facts, hopes
Andrea Cortegiani et al.
Critical Care 2020 24:210
Editorial
Published on: 8 May 2020

Use of triiodothyronine to treat critically ill COVID-19 patients: a new clinical trial
Constantinos Pantos et al.
Research Letter 
Published on: 8 May 2020

COVID-19 pandemic, healthcare providers’ contamination and death: an international view
Hossein Hassanian-Moghaddam, Nasim Zamani and Ali-Asghar Kolahi
Critical Care 2020 24:208
Letter
Published on: 8 May 2020 

Our recommendations for acute management of COVID-19
Francesco Mojoli, Silvia Mongodi, Anita Orlando, et al.
Critical Care 2020 24:207
Editorial
Published on: 8 May 2020 
 

Avoiding hospital-related infections during the COVID-19 epidemic
Jiarong Ye, Liqi Yang, Xiaotu Xi, et al.
Critical Care 2020 24:206
Editorial
Published on: 8 May 2020 

COVID-19 and ECMO: the interplay between coagulation and inflammation—a narrative review
Mariusz Kowalewski, Dario Fina, Artur Słomka, et al. 
Critical Care 2020 24:205
Review
Published on: 8 May 2020

Ethics guidelines on COVID-19 triage—an emerging international consensus
Susanne Joebges and Nikola Biller-Andorno
Critical Care 2020 24:201
Editorial
Published on: 6 May 2020

Psychological stress of ICU nurses in the time of COVID-19
Xin Shen, Xiaoyue Zou, Xiaofeng Zhong, et al.
Critical Care 2020 24:200
Editorial
Published on: 6 May 2020

 Acute respiratory failure in COVID-19: is it “typical” ARDS?
Xu Li and Xiaochun Ma
Critical Care 2020 24:198
Review
Published on: 6 May 2020

Heating, ventilation and air conditioning (HVAC) in intensive care unit
Sai Saran, Mohan Gurjar, Arvind Baronia, et al. 
Critical Care 2020 24:194
Review
Published on: 6 May 2020 

Can computed tomography be a primary tool for COVID-19 detection? Evidence appraisal through meta-analysis
Edward Pei-Chuan Huang, Chih-Wei Sung, et al.
Critical Care 2020 24:193
Research Letter
Published on: 6 May 2020

Liver injury in critically ill patients with COVID-19: a case series
Filipe S. Cardoso, Rui Pereira and Nuno Germano
Critical Care 2020 24:190
Research Letter
Published on: 5 May 2020

Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China
Dawei Wang, Yimei Yin, Chang Hu, et al. 
Critical Care 2020 24:188
Research
Published on: 30 April 2020

 Soluble urokinase plasminogen activator receptor (suPAR) as an early predictor of severe respiratory failure in patients with COVID-19 pneumonia
Nikoletta Rovina, Karolina Akinosoglou, Jesper Eugen-Olsen, Salim Hayek, Jochen Reiser and Evangelos J. Giamarellos-Bourboulis
Critical Care 2020 24:187
Research Letter
Published on: 30 April 2020 

Shining a light on the evidence for hydroxychloroquine in SARS-CoV-2
Nicholas E. Ingraham, David Boulware, Matthew A. Sparks, et al.
Critical Care 2020 24:182
Commentary
Published on: 28 April 2020

Clinical determinants for fatality of 44,672 patients with COVID-19
Guangtong Deng, Mingzhu Yin, Xiang Chen and Furong Zeng
Critical Care 2020 24:179
Letter
Published on: 28 April 2020

The role of telemedicine during the COVID-19 epidemic in China—experience from Shandong province
Xuan Song, Xinyan Liu and Chunting Wang
Critical Care 2020 24:178
Editorial
Published on: 28 April 2020

COVID-19: ICU delirium management during SARS-CoV-2 pandemic
Katarzyna Kotfis, Shawniqua Williams Roberson, Jo Ellen Wilson, et al.
Critical Care 2020 24:176
Review
Published on: 28 April 2020

 Is a more aggressive COVID-19 case detection approach mitigating the burden on ICUs? Some reflections from Italy
Giulia Lorenzoni, Corrado Lanera, Danila Azzolina, Paola Berchialla and Dario Gregori
Critical Care 2020 24:175
Research Letter
Published on: 28 April 2020

Lung ultrasound findings in patients with COVID-19 pneumonia
Changyang Xing, Qiaoying Li, Hong Du, et al.
Critical Care 2020 24:174
Research Letter
Published on: 28 April 2020 

SARS-CoV-2 viral load in sputum correlates with risk of COVID-19 progression
Xia Yu, Shanshan Sun, Yu Shi, Hao Wang, et al.
Critical Care 2020 24:170
Research Letter
Published on: 23 April 2020

High-flow nasal cannula may be no safer than non-invasive positive pressure ventilation for COVID-19 patients
Kenneth E. Remy, John C. Lin and Philip A. Verhoef
Critical Care 2020 24:169
Research Letter
Published on: 23 April 2020

Managing COVID-19 in resource-limited settings: critical care considerations
Wen Ting Siow, Mei Fong Liew, Babu Raja Shrestha, et al.
Critical Care 2020 24:167
Editorial
Published on: 22 April 2020

Clinical ethics recommendations for the allocation of intensive care treatments in exceptional, resource-limited circumstances: the Italian perspective during the COVID-19 epidemic
Marco Vergano, Guido Bertolini, Alberto Giannini, et al.
Critical Care 2020 24:165
Editorial
Published on: 22 April 2020

The application of strong matrix management and PDCA cycle in the management of severe COVID-19 patients
Yuanchao Li, Hongliang Wang and Jundong Jiao
Critical Care 2020 24:157
Editorial
Published on: 17 April 2020

Acute kidney injury in SARS-CoV-2 infected patients
Vito Fanelli, Marco Fiorentino, Vincenzo Cantaluppi, et al. 
Critical Care 2020 24:155
Commentary
Published on: 16 April 2020

COVID-19 pneumonia: ARDS or not?
Luciano Gattinoni, Davide Chiumello and Sandra Rossi
Critical Care 2020 24:154
Editorial
Published on: 16 April 2020

A case of a readmitted patient who recovered from COVID-19 in Chengdu, China
Xiao-jin Li, Zhong-wei Zhang and Zhi-yong Zong
Critical Care 2020 24:152
Research Letter
Published on: 16 April 2020

Prognosis when using extracorporeal membrane oxygenation (ECMO) for critically ill COVID-19 patients in China: a retrospective case series
Yingchun Zeng, Zhongxiang Cai, Yunyan Xianyu, et al.
Critical Care 2020 24:148
Research Letter
Published on: 15 April 2020

The model of epidemic (COVID-19) prevention and control in rural of China
Bao Fu and Xiaoyun Fu
Critical Care 2020 24:146
Letter
Published on: 14 April 2020

How to transform a general hospital into an “infectious disease hospital” during the epidemic of COVID-19
Hongli He, Caiying Hu, Nian Xiong, et al. 
Critical Care 2020 24:145
Letter
Published on: 14 April 2020

Using echocardiography to guide the treatment of novel coronavirus pneumonia
Qian-Yi Peng, Xiao-Ting Wang and Li-Na Zhang
Critical Care 2020 24:143
Editorial
Published on: 10 April 2020

COVID-19 and the RAAS—a potential role for angiotensin II?
Laurence W. Busse, Jonathan H. Chow, Michael T. McCurdy and Ashish K. Khanna
Critical Care 2020 24:136
Editorial
Published on: 7 April 2020

Practice of novel method of bedside postpyloric tube placement in patients with coronavirus disease 2019
Shou-Tao Yuan, Wen-Hao Zhang, Lei Zou, et al.
Critical Care 2020 24:135
Letter
Published on: 7 April 2020

A new clinical trial to test high-dose vitamin C in patients with COVID-19
Anitra C. Carr
Critical Care 2020 24:133
Letter
Published on: 7 April 2020

A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19
Philip Keith, Matthew Day, Linda Perkins, et al.
Critical Care 2020 24:128
Editorial
Published on: 2 April 2020

Covid-19 in China: ten critical issues for intensive care medicine
Li Li, Shijin Gong and Jing Yan
Critical Care 2020 24:124
Editorial
Published on: 31 March 2020

 Special attention to nurses’ protection during the COVID-19 epidemic
Authors:Lishan Huang, Guanwen Lin, Li Tang, et al.
Critical Care 2020 24:120
Editorial
Published on: 27 March 2020

Familial cluster of COVID-19 infection from an asymptomatic
Jinjun Zhang, Sijia Tian, Jing Lou and Yuguo Chen
Critical Care 2020 24:119
Research Letter
Published on: 27 March 2020

Host susceptibility to severe COVID-19 and establishment of a host risk score: findings of 487 cases outside Wuhan
Yu Shi, Xia Yu, Hong Zhao, et al.
Critical Care 2020 24:108
Research Letter
Published on: 18 March 2020

 COVID-19 infection epidemic: the medical management strategies in Heilongjiang Province, China
Hongliang Wang, Sicong Wang and Kaijiang Yu
Critical Care 2020 24:107
Editorial
Published on: 18 March 2020

Safe patient transport for COVID-19
Mei Fong Liew, Wen Ting Siow, Ying Wei Yau and Kay Choong See
Critical Care 2020 24:94
Letter
Published on: 18 March 2020

Treatment of COVID-19: old tricks for new challenges
Anne Catherine Cunningham, Hui Poh Goh and David Koh
Critical Care 2020 24:91
Editorial
Published on: 16 March 2020

Coronavirus: just imagine…
Jean-Louis Vincent and Arthur S. Slutsky
Critical Care 2020 24:90
Editorial
Published on: 16 March 202

Preparing for COVID-19: early experience from an intensive care unit in Singapore
Mei Fong Liew, Wen Ting Siow, Graeme MacLaren and Kay Choong See
Critical Care 2020 24:83
Letter
Published on: 9 March 2020