Rosenbaum L. Facing Covid-19 in Italy - Ethics, Logistics, and Therapeutics on the Epidemic's Front Line. N Engl J Med. 2020.
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054–62.
WHO. Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected; interim guidance, May 27th. 2020 [cited 2020 July, 7th]; https://apps.who.int/iris/bitstream/handle/10665/332196/WHO-2019-nCoV-clinical-2020.5-eng.pdf?sequence=1&isAllowed=y.
Bello-Chavolla OY, Bahena-Lopez JP, Antonio-Villa NE, Vargas-Vazquez A, Gonzalez-Diaz A, Marquez-Salinas A et al. Predicting mortality due to SARS-CoV-2: a mechanistic score relating obesity and diabetes to COVID-19 outcomes in Mexico. J Clin Endocrin Metab. 2020;105(8).
Angeli E, Dalto S, Marchese S, Setti L, Bonacina M, Galli F, et al. Prognostic value of CT integrated with clinical and laboratory data during the first peak of the COVID-19 pandemic in Northern Italy: a nomogram to predict unfavorable outcome. Eur J Radiol. 2021;137:109612.
Ruan Q, Yang K, Wang W, Jiang L, Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan. China Intensive Care Med. 2020;46(5):846–8.
Xie J, Hungerford D, Chen H, Abrams ST, Li S, Wang G, et al. Development and external validation of a prognostic multivariable model on admission for hospitalized patients with COVID-19. medRxiv. 2020.
Shi Y, Yu X, Zhao H, Wang H, Zhao R, Sheng J. Host susceptibility to severe COVID-19 and establishment of a host risk score: findings of 487 cases outside Wuhan. Crit Care. 2020;24(1):108.
Sun H, Jain A, Leone MJ, Alabsi HS, Brenner LN, Ye E, et al. COVID-19 outpatient screening: a prediction score for adverse events. medRxiv. 2020.
Paglia S, Storti E, Magnacavallo A, Cianci V, Cibinel GA, Fabbri A, et al. Rapporto Prima Linea Covid-19 assetto organizzativo gestionale dei PS/DEA nell’ambito di focolaio epidemico o pre-epidemico. 2020 [cited 2020 July, 14th]; http://www.quotidianosanita.it/allegati/allegato3277121.pdf.
Bertolini G, Nattino G. Pazienti COVID-19: la cura inizia a casa. Un progetto di monitoraggio attivo a Casale Monferrato e Torino 2020 [cited 2020 July, 7th]; http://www.fondazionebuzziunicem.org/documents/459904/466757/COVID-lacurainziaacasa.pdf/66404644-6828-110a-8129-cd9cefadf581.
Greenhalgh T, Javid B, Knight M, Inada-Kim M. What is the efficacy and safety of rapid exercise tests for exertional desaturation in Covid-19? : Oxford Covid-19 evidence service; 2020; https://www.researchgate.net/publication/340934179_What_is_the_efficacy_and_safety_of_rapid_exercise_tests_for_exertional_desaturation_in_covid-19.
Goodacre S, Thomas B, Lee E, Sutton L, Loban A, Waterhouse S et al. Post-exertion oxygen saturation as a prognostic factor for adverse outcome in patients attending the emergency department with suspected COVID-19: a substudy of the PRIEST observational cohort study. Emerg Med J. 2020.
Wang S, Zha Y, Li W, Wu Q, Li X, Niu M, et al. A fully automatic deep learning system for COVID-19 diagnostic and prognostic analysis. Eur Respir J. 2020;56(2).
Bernheim A, Mei X, Huang M, Yang Y, Fayad ZA, Zhang N, et al. Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection. Radiology. 2020;295(3):200463.
Sands SA, Edwards BA, Kelly VJ, Davidson MR, Wilkinson MH, Berger PJ. A model investigation of the impact of ventilation-perfusion mismatch on oxygenation during apnea in preterm infants. J Theor Biol. 2010. https://doi.org/10.1016/j.jtbi.2010.03.041.
Sands SA, Edwards BA, Kelly VJ, Davidson MR, Wilkinson MH, Berger PJ. A model analysis of arterial oxygen desaturation during apnea in preterm infants. PLoS Comput Biol. 2009;5(12):e1000588.
Findley LJ, Ries AL, Tisi GM, Wagner PD. Hypoxemia during apnea in normal subjects: mechanisms and impact of lung volume. J Appl Physiol. 1983;55(6):1777–83.
Couzin-Frankel J. The mystery of the pandemic’s “happy hypoxia.” Science. 2020;368(6490):455–6.
Widysanto A, Wahyuni TD, Simanjuntak LH, Sunarso S, Siahaan SS, Haryanto H, et al. Happy hypoxia in critical COVID-19 patient: a case report in Tangerang, Indonesia. Physiol Rep. 2020;8(20):e14619.
Villadiego J, Ramírez-Lorca R, Cala F, Labandeira-García JL, Esteban M, Toledo-Aral JJ, et al. Is Carotid body infection responsible for silent hypoxemia in COVID-19 patients? Function. 2020;2(1).
Tobin MJ, Laghi F, Jubran A. Why COVID-19 silent hypoxemia is baffling to physicians. Am J Respir Crit Care Med. 2020
Gattinoni L, Marini JJ, Camporota L, et al. Reply to Tobin, Respiratory drive measurements do not signify conjectural patient self-inflicted lung injury. Am J Respir Crit Care Med. 2021;203(1):143–4.
Marini JJ, Gattinoni L. Management of COVID-19 respiratory distress. JAMA. 2020;323(22):2329–30.
Tobin MJ, Jubran A, Laghi F. Respiratory drive measurements do not signify conjectural patient self-inflicted lung injury. Am J Respir Crit Care Med. 2021;203(1):142–3.
Messineo L, Taranto-Montemurro L, Azarbarzin A, Oliveira Marques MD, Calianese N, White DP, et al. Breath-holding as a means to estimate the loop gain contribution to obstructive sleep apnoea. J Physiol. 2018;596(17):4043–56.
Stanley NN, Cunningham EL, Altose MD, Kelsen SG, Levinson RS, Cherniack NS. Evaluation of breath holding in hypercapnia as a simple clinical test of respiratory chemosensitivity. Thorax. 1975;30(3):337–43.
Trembach N, Zabolotskikh I. Breath-holding test in evaluation of peripheral chemoreflex sensitivity in healthy subjects. Respir Physiol Neurobiol. 2017;235:79–82.
Duca A, Piva S, Foca E, Latronico N, Rizzi M. Calculated Decisions: Brescia-COVID respiratory severity scale (BCRSS)/algorithm. Emerg Med Pract. 2020;22(5 Suppl):CD1–2.
Bruce CD, Vanden Berg ER, Pfoh JR, Steinback CD, Day TA. Prior oxygenation, but not chemoreflex responsiveness, determines breath-hold duration during voluntary apnea. Physiol Rep. 2021;9(1):e14664.
Marini JJ, Gattinoni L. Management of COVID-19 respiratory distress. JAMA. 2020.
Mascheroni D, Kolobow T, Fumagalli R, Moretti MP, Chen V, Buckhold D. Acute respiratory failure following pharmacologically induced hyperventilation: an experimental animal study. Intensive Care Med. 1988;15(1):8–14.
Esnault P, Cardinale M, Hraiech S, Goutorbe P, Baumstrack K, Prud'homme E, et al. High respiratory drive and excessive respiratory efforts predict relapse of respiratory failure in critically Ill patients with COVID-19. Am J Respir Crit Care Med. 2020.
Swenson KE, Ruoss SJ, Swenson ER. The pathophysiology and dangers of silent hypoxemia in COVID-19 lung injury. Ann Am Thoracic Soc. 2021.
Simonson TS, Baker TL, Banzett RB, Bishop T, Dempsey JA, Feldman JL, et al. Silent hypoxaemia in COVID-19 patients. J Physiol. 2021;599(4):1057–65.
Davidson JT, Whipp BJ, Wasserman K, Koyal SN, Lugliani R. Role of the carotid bodies in breath-holding. N Engl J Med. 1974;290(15):819–22.
Paton JY, Swaminathan S, Sargent CW, Keens TG. Hypoxic and hypercapnic ventilatory responses in awake children with congenital central hypoventilation syndrome. Am Rev Respir Dis. 1989;140(2):368–72.
Gigliotti F. Mechanisms of dyspnea in healthy subjects. Multidiscip Respir Med. 2010;5(3):195–201.
Kikuchi Y, Okabe S, Tamura G, Hida W, Homma M, Shirato K, et al. Chemosensitivity and perception of dyspnea in patients with a history of near-fatal asthma. N Engl J Med. 1994;330(19):1329–34.
Molfino NA, Nannini LJ, Martelli AN, Slutsky AS. Respiratory arrest in near-fatal asthma. N Engl J Med. 1991;324(5):285–8.