Critical Care

Aims and scope

Critical Care is a high-quality, peer-reviewed, international clinical medical journal. Critical Care aims to improve the care of critically ill patients by acquiring, discussing, distributing, and promoting evidence-based information relevant to intensivists. Critical Care aims to provide a comprehensive overview of the intensive care field.

AUXORA + CORTICOSTEROIDS AS A STANDARD OF CARE IN ADULTS WITH SEVERE COVID-19 PNEUMONIA

The COVID-19 pandemic has caused nearly 5.5 million deaths worldwide. In patients with severe COVID-19 pneumonia, broad dysregulated immune responses have been identified with patients showing elevations in a range of proinflammatory cytokines. Therapeutic treatments targeting specific immune pathways may thus prevent disease progression. Charles Bruen et al. in this phase 2, randomized, double-blind, placebo-controlled trial evaluate the addition of Auxora, a CRAC channel inhibitor, to corticosteroids as a standard of care in adults with severe COVID-19 pneumonia.

CEREBRAL VENOUS SINUS THROMBOSIS ASSOCIATED WITH THROMBOCYTOPENIA POST-VACCINATION FOR COVID-19

Cerebral venous sinus thrombosis (CVST) is a rare form of stroke generally occurring in younger patients (typically < 50 years old), predominantly women. Incidence is about 5–16 cases per 1 million people per year. CVST has been reported in COVID-19 patients associated with thrombocytopenia.
G.P. Castelli et al. here report signs and symptoms related to thromboembolism in a patient recently vaccinated vs SARS-CoV-2.

CALL FOR PAPERS: THE FUTURE OF INTENSIVE CARE MEDICINE

This new Thematic Series focus on all aspects related to the future of Intensive Care Medicine, including but not limited to: organization, staffing, monitoring systems, new therapies, future organ support systems, ethical aspects.

After so many negative randomized, controlled trials, that have evaluated a number of simplified therapeutic interventions that could be applied to large patient populations, people are turning their interest back to personalized medicine. This new Thematic Series will share thoughts based on scientific data and help the clinician to individualize the different aspects of the patient management.

This will be a series of commentaries focused on a particular aspect that changed in our ICU: the way we make rounds, we allow family presence, we monitor patients, we use echo techniques and apply renal replacement therapy, etc. These comments should bring some guidance to others to improve quality of care.

On this occasion, we are looking back at the great journal’s milestone achievements, highlighting a selection of the most impactful contents from the past 25 years and some authoritative opinions from the closest collaborators who contributed to the journal success.

25 Years of Critical Care

Go through a special selection of 25 Critical Care influential contributions, one per each publication year, starting from the very beginning of our journal's prestigious history.

Selected articles from the Annual Update in Intensive Care and Emergency Medicine 2022

Meeting Abstracts - 41st International Symposium on Intensive Care and Emergency Medicine

Critical Care strongly encourages Authors of Research articles and Review articles to submit a Graphical Abstract.

A graphical abstract is a figure that clearly and succinctly conveys the main message of your research (paper).

The goal of a graphical abstract is to attract readers' attention to the article and encourage them to read the whole paper, but also promote interdisciplinary scholarship and help readers quickly identify which papers are most relevant to their research interests.

See the journal Submission Guidelines for more info on how to prepare a Graphical Abstract
Research articles
Review articles

COVID-19 UPDATES

We collect here all most recent research updates on COVID-19 epidemics published in the journal to make them easily discoverable to the research community

HOW I...

What are the most challenging critical care issues?
See how they can be best approached and managed

Announcing In Review

Critical Care, in partnership with Research Square, is now offering In Review. Authors choosing this free optional service during the submission process will be able to:

- Share their work with fellow researchers to read, comment on, and cite even before publication
- Showcase their work to funders and others with a citable DOI while it is still under review
- Track their manuscript - including seeing when reviewers are invited, and when reports are received

See the full range of benefits in choosing In Review and how to opt in here and how the platform looks like here

Articles

Effect of abdominal weight training with and without cough machine assistance on lung function in the patients with prolonged mechanical ventilation: a randomized trial

Authors: Tsai-Yi Hung, Wen-Lan Wu, Ho-Chang Kuo, Shih-Feng Liu, Chia-Ling Chang, Hui-Chuan Chang, Yuh-Chyn Tsai and Jui-Fang Liu

Content type: Research 25 May 2022
A multicentre evaluation exploring the impact of an integrated health and social care intervention for the caregivers of ICU survivors

Authors: Joanne McPeake, Philip Henderson, Pamela MacTavish, Helen Devine, Malcolm Daniel, Phil Lucie, Lynn Bollan, Lucy Hogg, Mike MacMahon, Sharon Mulhern, Pauline Murray, Laura O’Neill, Laura Strachan, Theodore J. Iwashyna, Martin Shaw and Tara Quasim

Content type: Research 24 May 2022
Effect of erythromycin on mortality and the host response in critically ill patients with sepsis: a target trial emulation

Authors: Tom D. Y. Reijnders, Hessel Peters-Sengers, Lonneke A. van Vught, Fabrice Uhel, Marc J. M. Bonten, Olaf L. Cremer, Marcus J. Schultz, Martijn M. Stuiver and Tom van der Poll

Content type: Research 24 May 2022
Venous return and mean systemic filling pressure: physiology and clinical applications

Authors: Romain Persichini, Christopher Lai, Jean-Louis Teboul, Imane Adda, Laurent Guérin and Xavier Monnet

Content type: Review 24 May 2022
Difference of 11 years between two periods of VV-ECMO does not impact mortality in large centres: we are not sure

Authors: Patrick M. Honore, Sebastien Redant, Pharan Djimafo, Thierry Preseau, Bogdan Vasile Cismas, Keitiane Kaefer, Leonel Barreto Gutierrez, Sami Anane, Andrea Gallerani and Rachid Attou

Content type: Correspondence 23 May 2022

The original article was published in Critical Care 2022 26:34

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_{Editorial | 06 August 2019}
Is this patient really “(un)stable”? How to describe cardiovascular dynamics in critically ill patients
_{Jean-Louis Vincent, Maurizio Cecconi and Bernd Saugel}

_{Research | 01 August 2019}
Vitamin A deficiency in critically ill children with sepsis
_{Xuepeng Zhang, Kaiying Yang, Linwen Chen, Xuelian Liao, Liping Deng, Siyuan Chen and Yi Ji}

_{Letter | 30 July 2019}
Vitamin C administration in the critically ill: a summary of recent meta-analyses
^{Anitra C. Carr}

_{Research | 24 July 2019}
Association of sublingual microcirculation parameters and endothelial glycocalyx dimensions in resuscitated sepsis
^{Alexandros Rovas, Laura Mareen Seidel, Hans Vink, Timo Pohlkötter, Hermann Pavenstädt, Christian Ertmer, Michael Hessler and Philipp Kümpers}

_{Editorial | 04 July 2019}
How I manage intracranial hypertension
^{Chiara Robba and Giuseppe Citerio}

Body temperature correlates with mortality in COVID-19 patients

Authors: Serena Tharakan, Koichi Nomoto, Satoshi Miyashita and Kiyotake Ishikawa

Content type: Research Letter 5 June 2020

The Letter to this article has been published in Critical Care 2020 24:460
Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group

Authors: Rinaldo Bellomo, Claudio Ronco, John A Kellum, Ravindra L Mehta and Paul Palevsky

Content type: Research 24 May 2004
Weaning from mechanical ventilation

Authors: Inmaculada Alía and Andrés Esteban

Content type: Review 18 February 2000

The Erratum to this article has been published in Critical Care 2006 10:414
Management of bleeding and coagulopathy following major trauma: an updated European guideline

Authors: Donat R Spahn, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Daniela Filipescu, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Jean-Louis Vincent and Rolf Rossaint

Content type: Research 19 April 2013
How low is too low? Cardiac risks with anemia

Authors: Samir M Fakhry and Paola Fata

Content type: Review 14 June 2004

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Latest blogs

The psychological impact of intensive care

06 December 2018
The gender gap in critical care medicine: how are we doing globally?

04 October 2018
Big data, big ethics: how to handle research data from medical emergency settings?

13 September 2018

Editorials & Commentaries

Video Abstract: The digestive tract as the origin of systemic inflammation

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HAVE A LOOK AT MONTHLY MOST TRENDING ARTICLES

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Latest Supplements

41st International Symposium on Intensive Care and Emergency Medicine 2022

^{Meeting abstracts
Volume 26 Supplement 1
Brussels, Belgium | 22-25 March 2022}

40th International Symposium on Intensive Care and Emergency Medicine 2021

^{Meeting abstracts
Volume 25 Supplement 1
Brussels, Belgium | 31 August-3 September 2021}

40th International Symposium on Intensive Care and Emergency Medicine 2020 - Part 2

^{Meeting abstracts
Volume 24 Supplement 2
eISICEM 2020 | 15-18 September 2020}

40th International Symposium on Intensive Care and Emergency Medicine

^{Meeting abstracts
Volume 24 Supplement 1
Brussels, Belgium | 24-27 March 2020}

39th International Symposium on Intensive Care and Emergency Medicine

^{Meeting abstracts
Volume 23 Supplement 2
Brussels, Belgium | 19-22 March 2019}

38th International Symposium on Intensive Care and Emergency Medicine

^{Meeting abstracts
Volume 22 Supplement 1
Brussels, Belgium | 20-23 March 2018}

Future of Critical Care Medicine (FCCM) 2016

^{Reviews
Volume 21 Supplement 3}

9th International Symposium on Intensive Care and Emergency Medicine for Latin America

^{Meeting abstracts
Volume 21 Supplement 2
São Paulo, Brazil | June 14-17 2017}

Expedited peer review

We recognise that scientifically sound, high quality manuscripts are often turned away from broad-scope "high-impact" journals based on the issue of "general interest." Critical Care will consider rapid publication of such manuscripts if they are submitted together with the original peer reviewer reports, letter of rejection, and a rebuttal. Please also mention this in your cover letter.

Additional peer review may be necessary and the final decision will be made by the Editor.

Thematic Series

The future of Intensive Care Medicine

_{Edited by Prof Jean-Louis Vincent}

Personalized medicine in the ICU

_{Edited by Prof Jean-Louis Vincent}

How the COVID crisis changed our lives in the ICU

_{Edited by Prof Jean-Louis Vincent}

How I...

_{Edited by Prof Jean-Louis Vincent}

Acute Stroke Management

^{Edited by Prof Marek Mirski}

Influenza: A Decade After the 2009 Pandemic

^{Edited by Prof Adrienne Randolph}

Vasoplegia

^{Edited by Prof Lui Forni}

CPR

^{Edited by Prof Jerry Nolan}

The future of critical care

^{Edited by Prof Jean-Louis Vincent}

Physiology of the circulation

^{Edited by Prof Sheldon Magder}

Echography in critically ill patients

^{Edited by Prof Daniel De Backer}

Pyrexia in the ICU

^{Edited by Prof Lui Forni}

Acute Kidney Injury (AKI)

^{Edited by Prof Michael Joannidis}

Neurocritical care

^{Edited by Prof Fabio Taccone}

Prof Jean-Louis Vincent, Editor-in-Chief

Prof Vincent is Professor of intensive care at the University of Brussels and intensivist in the Department of Intensive Care at the Erasme University Hospital in Brussels. He is President of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM) and a Past-President of the Belgian Society of Intensive Care Medicine (SIZ), the European Society of Intensive Care Medicine (ESICM), the European Shock Society (ESS) and the International Sepsis Forum (ISF). He is member of the Royal Medical Academy of Belgium.

Aims and scope

CALL FOR PAPERS: THE FUTURE OF INTENSIVE CARE MEDICINE

CALL FOR PAPERS: PERSONALIZED MEDICINE IN THE ICU

CALL FOR PAPERS: HOW THE COVID-CRISIS CHANGED OUR LIVES IN THE ICU

We are proud to celebrate Critical Care's 25th Anniversary

Announcing In Review

Articles

Latest blogs

Video Abstract: The digestive tract as the origin of systemic inflammation

Latest Tweets

Latest Supplements

Expedited peer review

Thematic Series

How the COVID crisis changed our lives in the ICU

Prof Jean-Louis Vincent, Editor-in-Chief

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Critical Care

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