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Research
Critically ill patients with acute kidney injury (AKI) can be divided into two subphenotypes, resolving or nonresolving, on the basis of the trajectory of serum creatinine. It is unknown if the biology underly...
Critical Care 2017 21:217
Published on: 17 August 2017
Research
Troponin I (TnI) is frequently elevated in critical illness, but its interpretation is unclear. Our primary objectives in this study were to evaluate whether TnI is associated with hospital mortality and if th...
Critical Care 2017 21:216
Published on: 16 August 2017
Letter
Critical Care 2017 21:215
Published on: 16 August 2017
Research
Vasopressin is widely used for vasopressor support in septic shock patients, but experimental evidence suggests that selective V1A agonists are superior. The initial pharmacodynamic effects, pharmacokinetics, and...
Critical Care 2017 21:213
Published on: 15 August 2017
Research
Cirrhotic patients are susceptible to sepsis and critical illness-related corticosteroid insufficiency (CIRCI). Dehydroepiandrosterone sulfate (DHEAS) is a corticotropin-dependent adrenal androgen, which has i...
Critical Care 2017 21:214
Published on: 15 August 2017
Review
Methicillin-resistant Staphylococcus aureus (MRSA) infection is still a major global healthcare problem. Of concern is S. aureus bacteremia, which exhibits high rates of morbidity and mortality and can cause meta...
Critical Care 2017 21:211
Published on: 14 August 2017
Research
Blood glucose control in the intensive care unit (ICU) has the potential to save lives. However, maintaining blood glucose concentrations within a chosen target range is difficult in clinical practice and hold...
Critical Care 2017 21:212
Published on: 14 August 2017
Research
Despite many animal studies and clinical trials, mortality in sepsis remains high. This may be due to the fact that most experimental studies of sepsis employ young animals, whereas the majority of septic pati...
Critical Care 2017 21:210
Published on: 8 August 2017
Editorial
Autophagy is a catabolic process by which cells can dispose of damaged content and intracellular microorganisms. Recent evidence implicates autophagy as a crucial repair process necessary to recover from criti...
Critical Care 2017 21:209
Published on: 7 August 2017
Research
The fluid challenge is considered the gold standard for diagnosis of fluid responsiveness. The objective of this study was to describe the fluid challenge techniques reported in fluid responsiveness studies an...
Critical Care 2017 21:207
Published on: 4 August 2017
Viewpoint
Critical Care 2017 21:199
Published on: 4 August 2017
Editorial
Critical Care 2017 21:208
Published on: 4 August 2017
The original article was published in Critical Care 2017 21:161
Letter
Critical Care 2017 21:201
Published on: 4 August 2017
The original article was published in Critical Care 2017 21:101
Research
Sedation and analgesia are commonly required to relieve anxiety and pain in mechanically ventilated patients. Fentanyl and morphine are the most frequently used opioids. Remifentanil is a selective μ-opioid re...
Critical Care 2017 21:206
Published on: 3 August 2017
Letter
Critical Care 2017 21:198
Published on: 3 August 2017
Viewpoint
There is an ongoing debate regarding the efficacy of glycaemic control in critically ill patients. Here we briefly highlight the key function of elevated glucose in critically ill patients, namely, to enable e...
Critical Care 2017 21:202
Published on: 3 August 2017
Letter
Critical Care 2017 21:205
Published on: 3 August 2017
The original article was published in Critical Care 2017 21:81
Letter
Critical Care 2017 21:200
Published on: 2 August 2017
Editorial
Critical Care 2017 21:204
Published on: 2 August 2017
Letter
Critical Care 2017 21:203
Published on: 1 August 2017
The original article was published in Critical Care 2017 21:45
Research
Pre-hospital endotracheal intubation is frequently used for trauma patients in many emergency medical systems. Despite a wide range of publications in the field, it is debated whether the intervention is assoc...
Critical Care 2017 21:192
Published on: 31 July 2017
Review
Glucose management in intensive care unit (ICU) patients has been a matter of debate for almost two decades. Compared to intermittent monitoring systems, continuous glucose monitoring (CGM) can offer benefit i...
Critical Care 2017 21:197
Published on: 31 July 2017
Commentary
Critical Care 2017 21:195
Published on: 31 July 2017
Letter
Critical Care 2017 21:196
Published on: 31 July 2017
The original article was published in Critical Care 2017 21:90
Letter
Critical Care 2017 21:117
Published on: 30 July 2017
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