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  1. Content type: Research

    Intensive care unit (ICU) survivors have reduced long-term survival compared to the general population. Identifying parameters at ICU discharge that are associated with poor long-term outcomes may prove useful...

    Authors: Etienne Gayat, Alain Cariou, Nicolas Deye, Antoine Vieillard-Baron, Samir Jaber, Charles Damoisel, Qin Lu, Xavier Monnet, Isabelle Rennuit, Elie Azoulay, Marc Léone, Heikel Oueslati, Bertrand Guidet, Diane Friedman, Antoine Tesnière, Romain Sonneville…

    Citation: Critical Care 2018 22:8

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  2. Content type: Research

    Providing supplemental oxygen is fundamental in the management of mechanically ventilated patients. Increasing amounts of data show worse clinical outcomes associated with hyperoxia. However, these previous da...

    Authors: David Page, Enyo Ablordeppey, Brian T. Wessman, Nicholas M. Mohr, Stephen Trzeciak, Marin H. Kollef, Brian W. Roberts and Brian M. Fuller

    Citation: Critical Care 2018 22:9

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  3. Content type: Research

    Sepsis is an established global health priority with high mortality that can be curtailed through early recognition and intervention; as such, efforts to raise awareness are potentially impactful and increasin...

    Authors: Craig S. Jabaley, James M. Blum, Robert F. Groff and Vikas N. O’Reilly-Shah

    Citation: Critical Care 2018 22:7

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  4. Content type: Research

    Exposure keratopathy (EK) has a high incidence in critically ill patients. We aimed to determine the rate of EK in patients admitted to our intensive care unit (ICU), identify risk factors for developing EK an...

    Authors: Obaid Kousha, Zubaid Kousha and Jonathan Paddle

    Citation: Critical Care 2018 22:5

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  5. Content type: Research

    The multicentre randomised controlled PEPaNIC trial showed that withholding parenteral nutrition (PN) during the first week of critical illness in children was clinically superior to providing early PN. This s...

    Authors: Esther van Puffelen, Suzanne Polinder, Ilse Vanhorebeek, Pieter Jozef Wouters, Niek Bossche, Guido Peers, Sören Verstraete, Koen Felix Maria Joosten, Greet Van den Berghe, Sascha Cornelis Antonius Theodorus Verbruggen and Dieter Mesotten

    Citation: Critical Care 2018 22:4

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  6. Content type: Research

    High frequency percussive ventilation (HFPV) combines diffusive (high frequency mini-bursts) and convective ventilation patterns. Benefits include enhanced oxygenation and hemodynamics, and alveolar recruitmen...

    Authors: Thomas Godet, Matthieu Jabaudon, Raïko Blondonnet, Aymeric Tremblay, Jules Audard, Benjamin Rieu, Bruno Pereira, Jean-Marc Garcier, Emmanuel Futier and Jean-Michel Constantin

    Citation: Critical Care 2018 22:3

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  7. Content type: Research

    Percutaneous dilatational tracheostomy (PDT) in critically ill patients often involves bronchoscopic optical guidance. However, this procedure is not without disadvantages. Therefore, we aimed to study a recen...

    Authors: Jörn Grensemann, Lars Eichler, Sophie Kähler, Dominik Jarczak, Marcel Simon, Hans O. Pinnschmidt and Stefan Kluge

    Citation: Critical Care 2017 21:330

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  8. Content type: Research

    Intracranial hypertension (ICH) is a major cause of death after traumatic brain injury (TBI). Continuous hyperosmolar therapy (CHT) has been proposed for the treatment of ICH, but its effectiveness is controve...

    Authors: Karim Asehnoune, Sigismond Lasocki, Philippe Seguin, Thomas Geeraerts, Pierre François Perrigault, Claire Dahyot-Fizelier, Catherine Paugam Burtz, Fabrice Cook, Dominique Demeure dit latte, Raphael Cinotti, Pierre Joachim Mahe, Camille Fortuit, Romain Pirracchio, Fanny Feuillet, Véronique Sébille and Antoine Roquilly

    Citation: Critical Care 2017 21:328

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  9. Content type: Review

    Much of what we now do in Critical Care carries an air of urgency, a pressing need to discover and act, with priorities biased toward a reactive response. However, efficacy often depends not simply upon what w...

    Authors: John J. Marini

    Citation: Critical Care 2017 21(Suppl 3):317

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    This article is part of a Supplement: Volume 21 Supplement 3

  10. Content type: Review

    With imprecise definitions, inexact measurement tools, and flawed study execution, our clinical science often lags behind bedside experience and simply documents what appear to be the apparent faults or validi...

    Authors: John J. Marini, Daniel De Backer, Can Ince, Mervyn Singer, Frank Van Haren, Martin Westphal and Paul Wischmeyer

    Citation: Critical Care 2017 21(Suppl 3):315

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    This article is part of a Supplement: Volume 21 Supplement 3

  11. Content type: Review

    Pleural effusion (PLEFF), mostly caused by volume overload, congestive heart failure, and pleuropulmonary infection, is a common condition in critical care patients. Thoracic ultrasound (TUS) helps clinicians ...

    Authors: E. Brogi, L. Gargani, E. Bignami, F. Barbariol, A. Marra, F. Forfori and L. Vetrugno

    Citation: Critical Care 2017 21:325

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  12. Content type: Research

    The optimal time to initiate renal replacement therapy (RRT) in intensive care unit (ICU) patients with acute kidney injury (AKI) is unclear. We examined the impact of early RRT on long-term mortality, risk of...

    Authors: Søren Christiansen, Steffen Christensen, Lars Pedersen, Henrik Gammelager, J. Bradley Layton, M. Alan Brookhart and Christian Fynbo Christiansen

    Citation: Critical Care 2017 21:326

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  13. Content type: Research

    Circulatory shock is a common syndrome with a high mortality and limited therapeutic options. Despite its discovery and use in clinical and experimental settings more than a half-century ago, angiotensin II (A...

    Authors: Laurence W. Busse, Michael T. McCurdy, Osman Ali, Anna Hall, Huaizhen Chen and Marlies Ostermann

    Citation: Critical Care 2017 21:324

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  14. Content type: Review

    The acute respiratory distress (ARDS) lung is usually characterized by a high degree of inhomogeneity. Indeed, the same lung may show a wide spectrum of aeration alterations, ranging from completely gasless re...

    Authors: Luciano Gattinoni, Tommaso Tonetti and Michael Quintel

    Citation: Critical Care 2017 21(Suppl 3):312

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    This article is part of a Supplement: Volume 21 Supplement 3

  15. Content type: Review

    This paper introduces the concept of personalized physiological medicine that is specifically directed at the needs of the critically ill patient. This differs from the conventional view of personalized medici...

    Authors: Can Ince

    Citation: Critical Care 2017 21(Suppl 3):308

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    This article is part of a Supplement: Volume 21 Supplement 3

  16. Content type: Review

    Red blood cell (RBC) transfusion might be life-saving in settings with acute blood loss, especially uncontrolled haemorrhagic shock. However, there appears to be a catch-22 situation reflected by the facts tha...

    Authors: Susilo Chandra, Hrishikesh Kulkarni and Martin Westphal

    Citation: Critical Care 2017 21(Suppl 3):310

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    This article is part of a Supplement: Volume 21 Supplement 3

  17. Content type: Review

    An exaggerated, dysregulated host response to insults such as infection (i.e. sepsis), trauma and ischaemia-reperfusion injury can result in multiple organ dysfunction and death. While the focus of research in...

    Authors: Mervyn Singer

    Citation: Critical Care 2017 21(Suppl 3):309

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 3

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