Articles
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Citation: Critical Care 2023 27:44
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Toward nutrition improving outcome of critically ill patients: How to interpret recent feeding RCTs?
Although numerous observational studies associated underfeeding with poor outcome, recent randomized controlled trials (RCTs) have shown that early full nutritional support does not benefit critically ill pati...
Citation: Critical Care 2023 27:43 -
Impact of continuous hypertonic (NaCl 20%) saline solution on renal outcomes after traumatic brain injury (TBI): a post hoc analysis of the COBI trial
To evaluate if the increase in chloride intake during a continuous infusion of 20% hypertonic saline solution (HSS) is associated with an increase in the incidence of acute kidney injury (AKI) compared to stan...
Citation: Critical Care 2023 27:42 -
Trough concentration may not be a good target for polymyxin B therapeutic drug monitoring
Citation: Critical Care 2023 27:41 -
Image augmentation and automated measurement of endotracheal-tube-to-carina distance on chest radiographs in intensive care unit using a deep learning model with external validation
Chest radiographs are routinely performed in intensive care unit (ICU) to confirm the correct position of an endotracheal tube (ETT) relative to the carina. However, their interpretation is often challenging a...
Citation: Critical Care 2023 27:40 -
The difference in the association between included ECPR patients and neurological outcomes
Citation: Critical Care 2023 27:39 -
P-SILI in critically ill COVID-19 patients: Macklin effect and the choice of noninvasive ventilatory support type
Citation: Critical Care 2023 27:38 -
Pattern of disease and determinants of mortality among ICU patients on mechanical ventilator in Sub-Saharan Africa: a multilevel analysis
The global mortality rate of patients with MV is very high, despite a significant variation worldwide. Previous studies conducted in Sub-Saharan Africa among ICU patients focused on the pattern of admission an...
Citation: Critical Care 2023 27:37 -
Cytokine hemoadsorption with CytoSorb® in post-cardiac arrest syndrome, a pilot randomized controlled trial
Hemoadsorption (HA) might mitigate the systemic inflammatory response associated with post-cardiac arrest syndrome (PCAS) and improve outcomes. Here, we investigated the feasibility, safety and efficacy of HA ...
Citation: Critical Care 2023 27:36 -
Temperature control in adults after cardiac arrest: a survey of current clinical practice in Germany
Temperature control is recommended after out of hospital cardiac arrest (OHCA) by international guidelines. This survey aimed to investigate current clinical practice and areas of uncertainty.
Citation: Critical Care 2023 27:35 -
COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation
Recent single-center reports have suggested that community-acquired bacteremic co-infection in the context of Coronavirus disease 2019 (COVID-19) may be an important driver of mortality; however, these reports...
Citation: Critical Care 2023 27:34 -
Clinician perceptions of the impact of ICU family visiting restrictions during the COVID-19 pandemic: an international investigation
To guarantee the safety of the public, clinicians and patients during the COVID-19 pandemic, hospital visits were severely restricted internationally. There are limited data on the precise impact of these visi...
Citation: Critical Care 2023 27:33 -
Prognostic models for outcome prediction following in-hospital cardiac arrest using pre-arrest factors: a systematic review, meta-analysis and critical appraisal
Several prediction models of survival after in-hospital cardiac arrest (IHCA) have been published, but no overview of model performance and external validation exists. We performed a systematic review of the a...
Citation: Critical Care 2023 27:32 -
The safety and efficacy of mesenchymal stromal cells in ARDS: a meta-analysis of randomized controlled trials
Mesenchymal stromal cells (MSC) have shown potential efficacy in both animal and human trials of acute respiratory distress syndrome (ARDS). Especially during the COVID-19 pandemic, MSC was intensely studied f...
Citation: Critical Care 2023 27:31 -
Letter to the Editor regarding “Effect of ICU quality control indicators on VAP incidence rate and mortality: a retrospective study of 1267 hospitals in China”
Citation: Critical Care 2023 27:30 -
An updated “norepinephrine equivalent” score in intensive care as a marker of shock severity
Vasopressors and fluids are the cornerstones for the treatment of shock. The current international guidelines on shock recommend norepinephrine as the first-line vasopressor and vasopressin as the second-line ...
Citation: Critical Care 2023 27:29 -
Global critical care: a call to action
Critical care is underprioritized. A global call to action is needed to increase equitable access to care and the quality of care provided to critically ill patients. Current challenges to effective critical c...
Citation: Critical Care 2023 27:28 -
The cephalic vein catheterization: maybe yes, but when there is no alternative
Citation: Critical Care 2023 27:27 -
Effect of apneic oxygenation with intubation to reduce severe desaturation and adverse tracheal intubation-associated events in critically ill children
Determine if apneic oxygenation (AO) delivered via nasal cannula during the apneic phase of tracheal intubation (TI), reduces adverse TI-associated events (TIAEs) in children.
Citation: Critical Care 2023 27:26 -
Association of red blood cells and plasma transfusion versus red blood cell transfusion only with survival for treatment of major traumatic hemorrhage in prehospital setting in England: a multicenter study
In-hospital acute resuscitation in trauma has evolved toward early and balanced transfusion resuscitation with red blood cells (RBC) and plasma being transfused in equal ratios. Being able to deliver this rati...
Citation: Critical Care 2023 27:25 -
Chest physiotherapy guided by electrical impedance tomography in high-dependency unit patients with pulmonary diseases: an introduction of methodology and feasibility
Citation: Critical Care 2023 27:24 -
Variation in electroencephalography and neuroimaging for children receiving extracorporeal membrane oxygenation
Seizures, strokes, and intracranial hemorrhage are common and feared complications in children receiving extracorporeal membrane oxygenation (ECMO) support. Researchers and clinicians have proposed and deploye...
Citation: Critical Care 2023 27:23 -
Response to: In-hospital cardiac arrest: evidence and specificities of perioperative cardiac arrest
Citation: Critical Care 2023 27:22 -
Electric impedance tomography-guided PEEP titration reduces mechanical power in ARDS: a randomized crossover pilot trial
In patients with acute respiratory distress syndrome undergoing mechanical ventilation, positive end-expiratory pressure (PEEP) can lead to recruitment or overdistension. Current strategies utilized for PEEP t...
Citation: Critical Care 2023 27:21 -
Perioperative changes in fluid distribution and haemodynamics in acute high-risk abdominal surgery
Understanding the pathophysiology of fluid distribution in acute high-risk abdominal (AHA) surgery is essential in optimizing fluid management. There is currently no data on the time course and haemodynamic im...
Citation: Critical Care 2023 27:20 -
Severity scores for status epilepticus in the ICU: systemic illness also matters
Current prognostic scores for status epilepticus (SE) may not be adequate for patients in ICU who usually have more severe systemic conditions or more refractory episodes of SE. We aimed to compare the prognos...
Citation: Critical Care 2023 27:19 -
Using automatic speckle tracking imaging to measure diaphragm excursion and predict the outcome of mechanical ventilation weaning
The speckle tracking ultrasound is an innovative technology enabling distinct assessment of diaphragmatic movement, yet the relative data are scarce. In this pilot study, we sought to evaluate the predictive v...
Citation: Critical Care 2023 27:18 -
In-hospital cardiac arrest: evidence and specificities of perioperative cardiac arrest
Citation: Critical Care 2023 27:17 -
Association of ultra-early diffusion-weighted magnetic resonance imaging with neurological outcomes after out-of-hospital cardiac arrest
This study aimed to investigate the association between ultra-early (within 6 h after return of spontaneous circulation [ROSC]) brain diffusion-weighted magnetic resonance imaging (DW-MRI) and neurological out...
Citation: Critical Care 2023 27:16 -
The Sequential Organ Failure Assessment (SOFA) Score: has the time come for an update?
The Sequential Organ Failure Assessment (SOFA) score was developed more than 25 years ago to provide a simple method of assessing and monitoring organ dysfunction in critically ill patients. Changes in clinica...
Citation: Critical Care 2023 27:15 -
Temporal trends in mortality and provision of intensive care in younger women and men with acute myocardial infarction or stroke
Timely management of acute myocardial infarction (AMI) and acute stroke has undergone impressive progress during the last decade. However, it is currently unknown whether both sexes have profited equally from ...
Citation: Critical Care 2023 27:14 -
“THE MANTLE” bundle for minimizing cerebral hypoxia in severe traumatic brain injury
To ensure neuronal survival after severe traumatic brain injury, oxygen supply is essential. Cerebral tissue oxygenation represents the balance between oxygen supply and consumption, largely reflecting the ade...
Citation: Critical Care 2023 27:13 -
Efficacy and safety of corticosteroids in cardiac arrest: a systematic review, meta-analysis and trial sequential analysis of randomized control trials
Post-cardiac arrest, outcomes for most patients are poor, regardless of setting. Many patients who do achieve spontaneous return of circulation require vasopressor therapy to maintain organ perfusion. There is...
Citation: Critical Care 2023 27:12 -
The rapid detection of respiratory pathogens in critically ill children
Respiratory infections are the most common reason for admission to paediatric intensive care units (PICU). Most patients with lower respiratory tract infection (LRTI) receive broad-spectrum antimicrobials, des...
Citation: Critical Care 2023 27:11 -
Skin pigmentation bias in regional brain oximetry measurements?
Citation: Critical Care 2023 27:10 -
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
Baricitinib has shown efficacy in hospitalized patients with COVID-19, but no placebo-controlled trials have focused specifically on severe/critical COVID, including vaccinated participants.
Citation: Critical Care 2023 27:9 -
Valproic acid as adjuvant treatment for convulsive status epilepticus: a randomised clinical trial
Generalised convulsive status epilepticus (GCSE) is a medical emergency. Guidelines recommend a stepwise strategy of benzodiazepines followed by a second-line anti-seizure medicine (ASM). However, GCSE is unco...
Citation: Critical Care 2023 27:8 -
Association between early nutrition support and 28-day mortality in critically ill patients: the FRANS prospective nutrition cohort study
Current guidelines suggest the introduction of early nutrition support within the first 48 h of admission to the intensive care unit (ICU) for patients who cannot eat. In that context, we aimed to describe nut...
Citation: Critical Care 2023 27:7 -
Post-cardiac surgery fungal mediastinitis: clinical features, pathogens and outcome
The occurrence of mediastinitis after cardiac surgery remains a rare and severe complication associated with poor outcomes. Whereas bacterial mediastinitis have been largely described, little is known about th...
Citation: Critical Care 2023 27:6 -
MIRACLE2 and SCAI grade identify patients for early wakening after out-of-hospital cardiac arrest: a post hoc analysis of the THAW trial
Citation: Critical Care 2023 27:5 -
The effect of blood pressure on mortality following out-of-hospital cardiac arrest: a retrospective cohort study of the United Kingdom Intensive Care National Audit and Research Centre database
Hypotension following out-of-hospital cardiac arrest (OHCA) may cause secondary brain injury and increase mortality rates. Current guidelines recommend avoiding hypotension. However, the optimal blood pressure...
Citation: Critical Care 2023 27:4 -
Epidemiology and outcomes of early-onset AKI in COVID-19-related ARDS in comparison with non-COVID-19-related ARDS: insights from two prospective global cohort studies
Acute kidney injury (AKI) is a frequent and severe complication of both COVID-19-related acute respiratory distress syndrome (ARDS) and non-COVID-19-related ARDS. The COVID-19 Critical Care Consortium (CCCC) h...
Citation: Critical Care 2023 27:3 -
The rate and assessment of muscle wasting during critical illness: a systematic review and meta-analysis
Patients with critical illness can lose more than 15% of muscle mass in one week, and this can have long-term detrimental effects. However, there is currently no synthesis of the data of intensive care unit (I...
Citation: Critical Care 2023 27:2 -
Clustering of critically ill patients using an individualized learning approach enables dose optimization of mobilization in the ICU
While early mobilization is commonly implemented in intensive care unit treatment guidelines to improve functional outcome, the characterization of the optimal individual dosage (frequency, level or duration) ...
Citation: Critical Care 2023 27:1 -
In Reply: Costa et al
Citation: Critical Care 2022 26:407 -
Publisher Correction to: A universal predictive and mechanistic urinary peptide signature in acute kidney injury
Citation: Critical Care 2022 26:406 -
Effect of ICU quality control indicators on VAP incidence rate and mortality: a retrospective study of 1267 hospitals in China
To investigate the effects of ICU quality control indicators on the VAP incidence rate and mortality in China throughout 2019.
Citation: Critical Care 2022 26:405 -
Intraoperative extracorporeal blood purification therapy during major septic vascular surgery
Citation: Critical Care 2022 26:404 -
Breath-by-breath P0.1 measured on quasi-occlusion via Hamilton C6 may result in underestimation of respiratory drive and inspiratory effort
We aimed to identify the threshold for P0.1 in a breath-by-breath manner measured by the Hamilton C6 on quasi-occlusion for high respiratory drive and inspiratory effort. In this prospective observational stud...
Citation: Critical Care 2022 26:403 -
Effect of high-flow oxygen versus T-piece ventilation strategies during spontaneous breathing trials on weaning failure among patients receiving mechanical ventilation: a randomized controlled trial
A spontaneous breathing trial (SBT) is used to determine whether patients are ready for extubation, but the best method for choosing the SBT strategy remains controversial. We investigated the effect of high-f...
Citation: Critical Care 2022 26:402
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- ISSN: 1364-8535 (electronic)