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  1. A previous retrospective single-centre study suggested that the percentage of time spent with cerebral perfusion pressure (CPP) below the individual lower limit of reactivity (LLR) is associated with mortality...

    Authors: Erta Beqiri, Frederick A. Zeiler, Ari Ercole, Michal M. Placek, Jeanette Tas, Joseph Donnelly, Marcel J. H. Aries, Peter J. Hutchinson, David Menon, Nino Stocchetti, Marek Czosnyka and Peter Smielewski
    Citation: Critical Care 2023 27:194
    Content type: Research Published on:

    The Matters Arising to this article has been published in Critical Care 2023 27:311

  2. Multiple organ dysfunction syndrome (MODS) is an important cause of post-operative morbidity and mortality for children undergoing cardiac surgery requiring cardiopulmonary bypass (CPB). Dysregulated inflammat...

    Authors: Alexis L. Benscoter, Jeffrey A. Alten, Mihir R. Atreya, David S. Cooper, Jonathan W. Byrnes, David P. Nelson, Nicholas J. Ollberding and Hector R. Wong
    Citation: Critical Care 2023 27:193
    Content type: Research Published on:

  5. The goal of hemodynamic resuscitation is to optimize the microcirculation of organs to meet their oxygen and metabolic needs. Clinicians are currently blind to what is happening in the microcirculation of orga...

    Authors: J. Duranteau, D. De Backer, K. Donadello, N. I. Shapiro, S. D. Hutchings, A. Rovas, M. Legrand, A. Harrois and C. Ince
    Citation: Critical Care 2023 27:190
    Content type: Review Published on:

    The Matters Arising to this article has been published in Critical Care 2023 27:352

  6. Sodium glucose co-transporter-2 (SGLT2) inhibitors improve long-term cardiovascular and renal outcomes in individuals with type 2 diabetes. However, the safety of SGLT2 inhibitors in ICU patients with type 2 d...

    Authors: Johan Mårtensson, Salvatore Lucio Cutuli, Eduardo A. Osawa, Fumitaka Yanase, Lisa Toh, Luca Cioccari, Nora Luethi, Akinori Maeda and Rinaldo Bellomo
    Citation: Critical Care 2023 27:189
    Content type: Research Published on:

    The Correspondence to this article has been published in Critical Care 2023 27:225

    The Correspondence to this article has been published in Critical Care 2023 27:204

  7. Intensive Care Unit (ICU) COVID-19 survivors may present long-term cognitive and emotional difficulties after hospital discharge. This study aims to characterize the neuropsychological dysfunction of COVID-19 ...

    Authors: Marta Godoy-González, Guillem Navarra-Ventura, Gemma Gomà, Candelaria de Haro, Cristina Espinal, Cristina Fortià, Natalia Ridao, Nuria Miguel Rebanal, Laia Oliveras-Furriols, Carles Subirà, Mercè Jodar, Verónica Santos-Pulpón, Leonardo Sarlabous, Rafael Fernández, Ana Ochagavía, Lluís Blanch…
    Citation: Critical Care 2023 27:188
    Content type: Research Published on:

  9. Critical illness is a continuum, but patient care is often fragmented. Value-based critical care focuses on the overall health of the patient, not on an episode of care. The “ICU without borders” model incorpo...

    Authors: Marlies Ostermann and Jean-Louis Vincent
    Citation: Critical Care 2023 27:186
    Content type: Perspective Published on:

  16. Sepsis-associated encephalopathy (SAE) is frequent in septic patients. Electroencephalography (EEG) is very sensitive to detect early epileptic abnormalities, such as seizures and periodic discharges (PDs), an...

    Authors: Lorenzo Ferlini, Christelle Maenhout, Ilaria Alice Crippa, Armin Alvaro Quispe-Cornejo, Jacques Creteur, Fabio Silvio Taccone and Nicolas Gaspard
    Citation: Critical Care 2023 27:179
    Content type: Research Published on:

  17. The aim of this study was to investigate the physiological impact of airway pressure release ventilation (APRV) on patients with early moderate-to-severe acute respiratory distress syndrome (ARDS) by electrica...

    Authors: Ruiting Li, Yongran Wu, Hongling Zhang, Azhen Wang, Xin Zhao, Shiying Yuan, Le Yang, Xiaojing Zou, You Shang and Zhanqi Zhao
    Citation: Critical Care 2023 27:178
    Content type: Brief Report Published on:

  19. Electrical impedance tomography (EIT) can be used to assess ventilation/perfusion (V/Q) mismatch within the lungs. Several methods have been proposed, some of them neglecting the absolute value of alveolar ventil...

    Authors: Samuel Tuffet, Tommaso Maraffi, Matthieu Lacheny, François Perier, Anne-Fleur Haudebourg, Mohamed Ahmed Boujelben, Glasiele Alcala, Armand Mekontso-Dessap and Guillaume Carteaux
    Citation: Critical Care 2023 27:176
    Content type: Brief Report Published on:

  20. High dose vasopressors portend poor outcome in vasodilatory shock. We aimed to evaluate the impact of baseline vasopressor dose on outcomes in patients treated with angiotensin II (AT II).

    Authors: Patrick M. Wieruszewski, Rinaldo Bellomo, Laurence W. Busse, Kealy R. Ham, Alexander Zarbock, Ashish K. Khanna, Adam M. Deane, Marlies Ostermann, Richard G. Wunderink, David W. Boldt, Stew Kroll, Chuck R. Greenfeld, Tony Hodges and Jonathan H. Chow
    Citation: Critical Care 2023 27:175
    Content type: Research Published on:

    The Comment to this article has been published in Critical Care 2023 27:210

  21. Several measurements have been used to predict the success of weaning from mechanical ventilation; however, their efficacy varies in different studies. In recent years, diaphragmatic ultrasound has been used f...

    Authors: Henry M. Parada-Gereda, Adriana L. Tibaduiza, Alejandro Rico-Mendoza, Daniel Molano-Franco, Victor H. Nieto, Wanderley A. Arias-Ortiz, Purificación Perez-Terán and Joan R. Masclans
    Citation: Critical Care 2023 27:174
    Content type: Perspective Published on:

  22. This study aims to provide an updated assessment of the efficacy of optimized enteral nutrition (EN) delivery by implementing the volume-based feeding (VBF) protocol in critically ill patients.

    Authors: Lu Wang, Yu Wang, Hua-Xin Li, Rui-peng Zhang, Li Chang, Jun Zeng and Hua Jiang
    Citation: Critical Care 2023 27:173
    Content type: Review Published on:

  25. To evaluate the heterogeneity in the definition of delirium in randomized controlled trials (RCTs) included in meta-analyses of delirium in intensive care units (ICUs) and to explore whether intervention effec...

    Authors: Lucie Collet, Aymeric Lanore, Camille Alaterre, Jean-Michel Constantin, Guillaume L. Martin, Agnès Caille, Arthur James and Agnès Dechartres
    Citation: Critical Care 2023 27:170
    Content type: Research Published on:

  26. Authors: Peter J. McGuigan, Elisa Giallongo, Bronagh Blackwood, James Doidge, David A. Harrison, Alistair D. Nichol, Kathryn M. Rowan, Manu Shankar‑Hari, Markus B. Skrifvars, Karen Thomas and Danny F. McAuley
    Citation: Critical Care 2023 27:169
    Content type: Publisher Correction Published on:

    The original article was published in Critical Care 2023 27:4

  28. Identifying patterns within ICU medication regimens may help artificial intelligence algorithms to better predict patient outcomes; however, machine learning methods incorporating medications require further d...

    Authors: Andrea Sikora, Alireza Rafiei, Milad Ghiasi Rad, Kelli Keats, Susan E. Smith, John W. Devlin, David J. Murphy, Brian Murray and Rishikesan Kamaleswaran
    Citation: Critical Care 2023 27:167
    Content type: Research Published on:

  29. Neisseria meningitidis is the leading responsible bacterium of Purpura Fulminans (PF) accounting for two thirds of PF. Skin biopsy is a simple and minimally invasive exam allowing to perform skin culture and poly...

    Authors: Damien Contou, Gaëtan Béduneau, Charlotte Rabault, Romain Sonneville, Antoine Marchalot, Rémi Coudroy, Damien Roux, Martin Cour, Julien Massol, Sébastien Préau and Nicolas de Prost
    Citation: Critical Care 2023 27:166
    Content type: Brief Report Published on:

  31. Polymyxin B is the first-line therapy for Carbapenem-resistant organism (CRO) nosocomial pneumonia. However, clinical data for its pharmacokinetic/pharmacodynamic (PK/PD) relationship are limited. This study a...

    Authors: Tiantian Tang, Ying Li, Ping Xu, Yanjun Zhong, Min Yang, Wanjun Ma, Daxiong Xiang, Bikui Zhang and Yangang Zhou
    Citation: Critical Care 2023 27:164
    Content type: Research Published on:

  32. The benefit–risk ratio of prophylactic non-invasive ventilation (NIV) and high-flow nasal oxygen therapy (HFNC-O2) during the early stage of blunt chest trauma remains controversial because of limited data. The m...

    Authors: Cédric Carrié, Benjamin Rieu, Antoine Benard, Kilian Trin, Laurent Petit, Alexandre Massri, Igor Jurcison, Guillaume Rousseau, David Tran Van, Marie Reynaud Salard, Jeremy Bourenne, Albrice Levrat, Laurent Muller, Damien Marie, Claire Dahyot-Fizelier, Julien Pottecher…
    Citation: Critical Care 2023 27:163
    Content type: Research Published on:

  33. Older adults are at high-risk for a post-operative intensive care unit (ICU) admission, yet little is known about the impact of these admissions on quality of life. The objective of this study was to evaluate ...

    Authors: Bourke W. Tillmann, Julie Hallet, Rinku Sutradhar, Matthew P. Guttman, Natalie Coburn, Tyler R. Chesney, Jesse Zuckerman, Alyson Mahar, Wing C. Chan and Barbara Haas
    Citation: Critical Care 2023 27:162
    Content type: Research Published on:

  34. Prognosis after resuscitation from cardiac arrest (CA) remains poor, with high morbidity and mortality as a result of extensive cardiac and brain injury and lack of effective treatments. Hypertonic sodium lact...

    Authors: Filippo Annoni, Fuhong Su, Lorenzo Peluso, Ilaria Lisi, Enrico Caruso, Francesca Pischiutta, Elisa Gouvea Bogossian, Bruno Garcia, Hassane Njimi, Jean-Louis Vincent, Nicolas Gaspard, Lorenzo Ferlini, Jacques Creteur, Elisa R. Zanier and Fabio Silvio Taccone
    Citation: Critical Care 2023 27:161
    Content type: Research Published on:

  35. Authors: David Pérez-Torres, Pedro Alberto Merino-García, Isabel Canas-Pérez, Cristina Cuenca-Rubio, Guillermo Javier Posadas-Pita, Cristina Colmenero-Calleja, Thalia Gloria Ticona-Espinoza and Cristina Díaz-Rodríguez
    Citation: Critical Care 2023 27:160
    Content type: Correspondence Published on:

    The original article was published in Critical Care 2023 27:15

    The Correspondence to this article has been published in Critical Care 2023 27:182

  37. The development of stratification tools based on the assessment of circulating mRNA of genes involved in the immune response is constrained by the heterogeneity of septic patients. The aim of this study is to ...

    Authors: Maxime Bodinier, Guillaume Monneret, Marie Casimir, Aurore Fleurie, Filippo Conti, Fabienne Venet, Marie-Angélique Cazalis, Elisabeth Cerrato, Estelle Peronnet, Thomas Rimmelé, Anne-Claire Lukaszewicz, Karen Brengel-Pesce and Jean-François Llitjos
    Citation: Critical Care 2023 27:158
    Content type: Research Published on:

  38. At the bedside, assessing the risk of ventilator-induced lung injury (VILI) requires parameters readily measured by the clinician. For this purpose, driving pressure (DP) and end-inspiratory static ‘plateau’ pres...

    Authors: John J. Marini, Lauren T. Thornton, Patricia R. M. Rocco, Luciano Gattinoni and Philip S. Crooke
    Citation: Critical Care 2023 27:157
    Content type: Perspective Published on:

  39. There is insufficient evidence to guide ventilatory targets in acute brain injury (ABI). Recent studies have shown associations between mechanical power (MP) and mortality in critical care populations. We aime...

    Authors: Sarah Wahlster, Monisha Sharma, Shaurya Taran, James A. Town, Robert D. Stevens, Raphaël Cinotti, Karim Asehoune, Paolo Pelosi and Chiara Robba
    Citation: Critical Care 2023 27:156
    Content type: Research Published on:

  40. The mechanisms used by SARS-CoV-2 to induce major adverse cardiac events (MACE) are unknown. Thus, we aimed to determine if SARS-CoV-2 can induce necrotic cell death to promote MACE in patients with severe COV...

    Authors: Rosana Wiscovitch-Russo, Elsa D. Ibáñez-Prada, Cristian C. Serrano-Mayorga, Benjamin L. Sievers, Maeve A. Engelbride, Surya Padmanabhan, Gene S. Tan, Sanjay Vashee, Ingrid G. Bustos, Carlos Pachecho, Lina Mendez, Peter H. Dube, Harinder Singh, Luis Felipe Reyes and Norberto Gonzalez-Juarbe
    Citation: Critical Care 2023 27:155
    Content type: Research Published on:

  42. An increase in cardiac index (CI) during an end-expiratory occlusion test (EEOt) predicts fluid responsiveness in ventilated patients. However, if CI monitoring is unavailable or the echocardiographic window i...

    Authors: Sonia D’Arrigo, Antonio Maria Dell’Anna, Claudio Sandroni, Antonio Messina, Sofia Cacciola, Chiara Pacini and Massimo Antonelli
    Citation: Critical Care 2023 27:153
    Content type: Research Published on:

  43. Heterogeneity is an inherent nature of ARDS. Recruitment-to-inflation ratio has been developed to identify the patients who has lung recruitablity. This technique might be useful to identify the patients that ...

    Authors: Hiroki Taenaka, Takeshi Yoshida, Haruka Hashimoto, Andi Muhammad Fadlillah Firstiogusran, Suguru Ishigaki, Hirofumi Iwata, Yusuke Enokidani, Hironori Ebishima, Naoko Kubo, Moe Koide, Yukiko Koyama, Ryota Sakaguchi, Natsuko Tokuhira, Yu Horiguchi, Akinori Uchiyama and Yuji Fujino
    Citation: Critical Care 2023 27:152
    Content type: Research Published on:

  45. ICU risk assessment tools, routinely used for predicting population outcomes, are not recommended for evaluating individual risk. The state of health of single patients is mostly subjectively assessed to infor...

    Authors: Lucas Boeck, Hans Pargger, Peter Schellongowski, Charles-Edouard Luyt, Marco Maggiorini, Kathleen Jahn, Grégoire Muller, Rene Lötscher, Evelyne Bucher, Nadine Cueni, Thomas Staudinger, Jean Chastre, Martin Siegemund, Michael Tamm and Daiana Stolz
    Citation: Critical Care 2023 27:150
    Content type: Research Published on:

  50. Optimal noninvasive respiratory support for patients with hypoxemic respiratory failure should minimize work of breathing without increasing the transpulmonary pressure. Recently, an asymmetrical high flow nas...

    Authors: Douglas Slobod, Elena Spinelli, Stefania Crotti, Alfredo Lissoni, Alessandro Galazzi, Giacomo Grasselli and Tommaso Mauri
    Citation: Critical Care 2023 27:145
    Content type: Research Published on:
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  • ISSN: 1364-8535 (electronic)

Critical Care

ISSN: 1364-8535