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Arginine vasopressin is a vasoactive drug commonly used in distributive shock states including mixed shock with a cardiac component. However, the direct effect of arginine vasopressin on the function of the is...
Physiological determinants of weaning success and failure are usually studied in ventilator-supported patients, comparing those who failed a trial of spontaneous breathing with those who tolerated such a trial...
Critically ill patients and families rely upon physicians to provide estimates of prognosis and recommendations for care. Little is known about patient and clinician factors which influence these predictions. ...
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 3
This issue's Recently published papers commentary considers the popular and muddy waters of glycaemic control, stops briefly to ponder the incidence of pulmonary embolus in acute exacerbations of chronic obstr...
Blood glucose levels and insulin resistance in critically ill patients on admission to intensive care units (ICUs) have been identified as factors influencing mortality. The pathogenesis of insulin resistance ...
Recent epidemiologic literature indicates that candidal species resistant to azoles are becoming more prevalent in the face of increasing incidence of hospitalizations with candidemia. Echinocandins, a new cla...
Reade et al. studied 20 agitated intubated patients in a pilot open-label trial comparing the efficacy of dexmedetomidine versus haloperidol in facilitating extubation. While the study design had limitations, whi...
Severe sepsis, septic shock, and resulting organ failure represent the most common cause of death in intensive care medicine, with mortality ranging from 40% to 70%. It is still unclear whether necrosis or apo...
Our goal was to assess the effects of titration of a norepinephrine infusion to increasing levels of mean arterial pressure (MAP) on sublingual microcirculation.
In critical illness, the association of hypoglycemia, blood glucose (BG) variability and outcome are not well understood. We describe the incidence, clinical factors and outcomes associated with an early hypog...
The past 15 years have seen major advances in our understanding of severity assessment in community-acquired pneumonia (CAP). Prognostic tools have been promoted to guide all major management decisions in CAP,...
Hyperlactatemia is frequent in critically ill patients and is often used as a marker of adverse outcome. However, studies to date have focused on selected intensive care unit (ICU) populations. We sought to de...
Critical Care