Volume 13 Supplement 3
A comparative study between conventional and antiseptic impregnated central venous catheters
© BioMed Central Ltd 2009
Published: 23 June 2009
Central venous catheters (CVCs) are very useful in the management of patients hospitalized in the ICU, but are not devoid of complications. Among the complications related to permanence of CVCs, infection stands out. This may increase the morbidity, mortality, costs and length of stay in the ICU. A comparative study between antiseptic-impregnated and standard catheters is therefore of great value.
To compare the duration of standard CVCs with those impregnated with chlorhexidine–silver sulfadiazine.
A prospective, randomized, alternate, nonblind study.
Central venous access was taken, alternating the type of CVC used in each patient. The following were recorded for each patient: sex, age, APACHE II score, site of the puncture, reason for withdrawal of the catheter and the type of catheter used. The tip of the catheter was cultured (qualitative). The patients were divided: Group I (41 patients, 54 punctures) used the standard CVC, and Group II (38 patients, 54 punctures) used the impregnated CVC.
P value (ORa)
36.1 to 63.9
40.4 to 68.4
Subclavian vein as predominant site of puncture
32.6 to 60.4
51.7 to 78.5
GLASGOW ≤ 8
45.0 to 72.4
42.3 to 70.2
APACHE II score (average)
64.4 to 88.0
35.1 to 63.1
Average length (excluding death)
9.3 to 31.4
6.7 to 27.6
The length of stay with the use of impregnated CVCs was higher (15.43 days) than the standard CVCs (10.86 days). The rate of colonization was higher in the standard CVC. Patients who require a CVC for long periods have benefited with the use of impregnated CVCs, because they present long-term use and lower rates of colonization, avoiding complications related to the procedure of successive punctures and related to the permanence of the catheters. In view of the clinical benefits already mentioned, the benefit gained by the use of antiseptic-impregnated catheters compensated for the initial expensive cost of 40%.