Volume 13 Supplement 3

Fifth International Symposium on Intensive Care and Emergency Medicine for Latin America

Open Access

Epidemiology and clinical characterization of patients with acute respiratory failure admitted to a general ICU

  • RHR Oliveira1,
  • M Trece1,
  • N Chagas1 and
  • JMM Teles1
Critical Care200913(Suppl 3):P42

https://doi.org/10.1186/cc7844

Published: 23 June 2009

Objective

To study the prevalence and mortality of ARF and characteristics of the patients with ARF admitted to a general ICU.

Methods

During 6 months, all adult patients admitted to a 17-bed ICU in Salvador, Bahia, Brazil who had ARF defined as a patient receiving mechanical ventilation for more than 24 hours were prospectively studied.

Results

From March to August 2008, there were 411 admissions to the ICU. From these, 82 (20%) patients received mechanical ventilation for more than 24 hours with a median duration of 4 days (varied from 1 to 69 days). The characteristics of patients with ARF are presented in Table 1. These patients were older than the total population admitted to the ICU (68 vs 65 years, P < 0.05), had higher APACHE II score (19 vs 13, P < 0.0001), higher ICU stay (10.5 vs 3.0 days, P < 0.001) and higher mortality (51.2 vs 17.5%, P < 0.0001). Mortality of ARF patients was associated with old age, odds ratio of 3.0 for death for patients older than 70 years (95% CI = 1.2 to 7.5), and development of complications in the ICU (OR = 8.4, 95% CI = 3.1 to 22.8).
Table 1

Characteristics of 82 patients with acute respiratory failure

Characteristic

Median (variation)

Age

68 (18 to 92)

APACHE II score

19 (4 to 32)

Sex male (n (%))

37 (45.1%)

Chronic disease (n (%))

77 (93.9%)

Length of stay in the ICU (days)

10.5 (1 to 71)

Cause of ARF (n (%))

 

   Sepsis

26 (31.7%)

   Altered level of consciousness

20 (24.4%)

   Shock

18 (21.9%)

   Pneumonia

13 (15.8%)

Complication in the ICU (n (%))

42 (51.2%)

   Multiple organ failure

12 (14.6%)

   Acute kidney injury

10 (12.2%)

   Ventilator-associated pneumonia

8 (9.7%)

Mortality in the ICU (n (%))

42 (51.2%)

Conclusion

ARF prevalence was 20% in the studied population. The main cause of ARF was sepsis, these patients were older, more severely ill, had higher ICU stay and mortality than the total population admitted to the ICU and were often complicated with multiple organ failure.

Authors’ Affiliations

(1)
UTI Adulto Hospital Salvador

Copyright

© BioMed Central Ltd 2009

Advertisement