Page 57 of 139
Microcirculatory blood flow, and notably gut perfusion, is important in the development of multiple organ failure in septic shock. We compared the effects of dopexamine and norepinephrine (noradrenaline) with ...
Thrombotic complications and coagulopathy frequently occur in COVID-19. However, the characteristics of COVID-19-associated coagulopathy (CAC) are distinct from those seen with bacterial sepsis-induced coagulopat...
To measure the mass transfer and clearance of procalcitonin (PCT) in patients with septic shock during continuous venovenous hemofiltration (CVVH), and to assess the mechanisms of elimination of PCT.
Vascular hyporeactivity is an important problem associated with sepsis. Although the mechanism involves inflammatory pathway activation ... some anti-inflammatory effects and improve outcomes in sepsis. Here, we ...
This prospective study investigated whether plasma ionized calcium concentration abnormalities and other electrolyte disturbances represent risk factors for the development of critical illness polyneuromyopath...
It is unclear to which level mean arterial blood pressure (MAP) should be increased during septic shock in order to improve outcome. In this study we investigated the association between MAP values of 70 mmHg ...
Evidence based medicine is an attempt to optimize the medical decision process through methods primarily based on evidence coming from meta-analyses, systematic reviews, and randomized controlled trials ("evid...
This article is part of a Supplement: Volume 19 Supplement 3
Decision-making in the intensive care unit is often very difficult. Although we are encouraged to make evidence-based decisions, this may be difficult for a number of reasons. To begin with, evidence may not e...
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), the major endothelial receptor for oxidized low-density lipoprotein, is also involved in leukocyte recruitment. Systemic leukocyte activation in sepsis
Pro-adrenomedullin (proADM) is helpful for individual risk assessment and outcome prediction in sepsis. A major cause of sepsis is community-acquired pneumonia (CAP). The...
One-hundred and fifty patients with P. aeruginosa HAP were evaluated. The 30-day mortality was 37.3% (56 of 150): 57.1% (24 of 42) and 29.6% (32 of 108) for patients with HAP by MBL-producing P. aeruginosa and by...
This review summarises key research papers in the fields of cardiology and intensive care published during 2007 in Critical Care. To create a context and for comparison with the papers described in the review, we...
We summarize original research in the field of critical care nephrology accepted or published in 2005 in Critical Care and, when considered relevant or directly linked to this research, in other journals. The art...
Post-cardiac arrest syndrome (PCAS) often leads to multiple organ dysfunction syndrome (MODS) with a poor prognosis. Endothelial and leukocyte activation after whole-body ischemia/reperfusion following resusci...
A data-collection form and instruction manual were created based on published recommendations, and completed for all consecutive critical care animal research (using mammals) publications from January to June 201...
Hyperlactatemia represents one prominent component of the metabolic response to sepsis. In critically ill patients, hyperlactatemia is...
Neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker of acute kidney injury (AKI), and levels reflect severity of disease in critically ill patients. However, continuous venovenous hemofiltration (...
Sensitive monitoring should be used when prescribing intravenous fluids for volume resuscitation. The extent and duration of tissue hypoperfusion determine the severity of cellular damage, which should be kept to...
This article is part of a Supplement: Volume 19 Supplement 3
Costly genetically engineered therapies, which threaten to cripple the health care industry economy and undermine the common good if applied indiscriminately, loom on the horizon. The spectrum of applicable ca...
This article is part of a Supplement: Volume 11 Supplement 2
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 17 Supplement 2
This article is part of a Supplement: Volume 11 Supplement 2
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 11 Supplement 2
This article is part of a Supplement: Volume 12 Supplement 5
This article is part of a Supplement: Volume 5 Supplement 3
This article is part of a Supplement: Volume 13 Supplement 1
This article is part of a Supplement: Volume 4 Supplement 1
This article is part of a Supplement: Volume 18 Supplement 1
This article is part of a Supplement: Volume 11 Supplement 2
This article is part of a Supplement: Volume 13 Supplement 1
This article is part of a Supplement: Volume 11 Supplement 2
This article is part of a Supplement: Volume 9 Supplement 1
This article is part of a Supplement: Volume 4 Supplement 1
This article is part of a Supplement: Volume 7 Supplement 3
This article is part of a Supplement: Volume 9 Supplement 2
This article is part of a Supplement: Volume 19 Supplement 2
This article is part of a Supplement: Volume 8 Supplement 1
This article is part of a Supplement: Volume 12 Supplement 2
This article is part of a Supplement: Volume 13 Supplement 1
This article is part of a Supplement: Volume 15 Supplement 1
This article is part of a Supplement: Volume 8 Supplement 1
This article is part of a Supplement: Volume 3 Supplement 1
This article is part of a Supplement: Volume 12 Supplement 2
This article is part of a Supplement: Volume 11 Supplement 3
Critical Care