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6921 result(s) for 'sepsis' within Critical Care

Page 48 of 139

  1. There were 7,689 eligible admissions. ICU mortality was 43.1% (3,312 deaths) and acute hospital mortality was 59.2% (4,239 deaths). ICU and hospital mortality increased with the number of organ failures on admiss...

    Authors: Peter A Hampshire, Catherine A Welch, Lawrence A McCrossan, Katharine Francis and David A Harrison
    Citation: Critical Care 2009 13:R137
    Content type: Research Published on:

  2. Platelets display a number of properties besides the crucial function of repairing damaged vascular endothelium and stopping bleeding; these are exploited to benefit patients receiving platelet component transfus...

    Authors: Olivier Garraud, Hind Hamzeh-Cognasse, Bruno Pozzetto, Jean-Marc Cavaillon and Fabrice Cognasse
    Citation: Critical Care 2013 17:236
    Content type: Review Published on:

  3. Thirty-two patients hospitalized with confirmed nvA(H1N1) infection were enrolled in the study: 21 patients with nvA(H1N1)-acute respiratory distress syndrome (ARDS) and 11 patients with mild disease. One group o...

    Authors: Natalia Hagau, Adriana Slavcovici, Daniel N Gonganau, Simona Oltean, Dan S Dirzu, Erika S Brezoszki, Mihaela Maxim, Constantin Ciuce, Monica Mlesnite, Rodica L Gavrus, Carmen Laslo, Radu Hagau, Magda Petrescu and Daniela M Studnicska
    Citation: Critical Care 2010 14:R203
    Content type: Research Published on:

  4. Decreased monocytic (m)HLA-DR expression is the most studied biomarker of sepsis-induced immunosuppression. To date, little is known about the relationship between sepsis characteristics, such as the site of infe...

    Authors: Guus P. Leijte, Thomas Rimmelé, Matthijs Kox, Niklas Bruse, Céline Monard, Morgane Gossez, Guillaume Monneret, Peter Pickkers and Fabienne Venet
    Citation: Critical Care 2020 24:110
    Content type: Research Published on:

  5. A total of 140 patients (54% boys, mean ± standard deviation Pediatric Risk of Mortality II score 15.0 ± 8.0, 23% sepsis) were included. Mean and peak uNGAL...P < 0.05). uNGAL concentrations rose (at least sixfol...

    Authors: Michael Zappitelli, Kimberly K Washburn, Ayse A Arikan, Laura Loftis, Qing Ma, Prasad Devarajan, Chirag R Parikh and Stuart L Goldstein
    Citation: Critical Care 2007 11:R84
    Content type: Research Published on:

  6. We evaluate an innovative device consisting of an enteral feeding tube equipped with a photoplethysmography (PPG) sensor in contact with the duodenal mucosa. This study aims to determine if the PPG signal, com...

    Authors: Matthias Jacquet-Lagrèze, Jeanne-Marie Bonnet-Garin, Bernard Allaouchiche, Olivia Vassal, Damien Restagno, Christian Paquet, Jean-Yves Ayoub, Jérôme Etienne, François Vandenesch, Olivier Daulwader and Stéphane Junot
    Citation: Critical Care 2014 18:R153
    Content type: Research Published on:

  7. Septic shock remains a major health care problem worldwide. Sepsis-induced immune alterations are thought to play ... exhibited a lower mortality in response to experimental sepsis. The objective of the present s...

    Authors: Caroline Guignant, Alain Lepape, Xin Huang, Hakim Kherouf, Laure Denis, Françoise Poitevin, Christophe Malcus, Aurélie Chéron, Bernard Allaouchiche, François Gueyffier, Alfred Ayala, Guillaume Monneret and Fabienne Venet
    Citation: Critical Care 2011 15:R99
    Content type: Research Published on:

  8. Severe or life threatening infections are common among patients in the intensive care unit (ICU). Most infections in the ICU are bacterial or fungal in origin and require antimicrobial therapy for clinical resolu...

    Authors: Marin H. Kollef, Andrew F. Shorr, Matteo Bassetti, Jean-Francois Timsit, Scott T. Micek, Andrew P. Michelson and Jose Garnacho-Montero
    Citation: Critical Care 2021 25:360
    Content type: Review Published on:

  9. Identifying new effective treatments for the acute respiratory distress syndrome (ARDS), including COVID-19 ARDS, remains a challenge. The field of ARDS investigation is moving increasingly toward innovative a...

    Authors: Katherine D. Wick, Daniel F. McAuley, Joseph E. Levitt, Jeremy R. Beitler, Djillali Annane, Elisabeth D. Riviello, Carolyn S. Calfee and Michael A. Matthay
    Citation: Critical Care 2021 25:404
    Content type: Review Published on:

  10. Secondary nosocomial infections, which are commonly caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) and vancomycin-resistant Enterococcus faecium (VRE), often develop in septic patients. This study ai...

    Authors: Sucheng Mu, Hao Xiang, Yuezhu Wang, Wei Wei, Xiangyu Long, Yi Han, Zhongshu Kuang, Yilin Yang, Feixiang Xu, Mingming Xue, Zhimin Dong, Chaoyang Tong, Huajun Zheng and Zhenju Song
    Citation: Critical Care 2022 26:68
    Content type: Research Published on:

  11. This narrative review summarizes the role of vitamin C in mitigating oxidative injury-induced microcirculatory impairment and associated organ failure in ischemia/reperfusion or sepsis. Preclinical studies show t...

    Authors: Heleen M Oudemans-van Straaten, Angelique ME Spoelstra-de Man and Monique C de Waard
    Citation: Critical Care 2014 18:460
    Content type: Review Published on:

  12. Septic-shock-associated acute kidney injury (SSAKI) carries high morbidity in the pediatric population. Effective treatment strategies are lacking, in part due to poor detection and prediction. There is a need...

    Authors: Rajit K Basu, Stephen W Standage, Natalie Z Cvijanovich, Geoffrey L Allen, Neal J Thomas, Robert J Freishtat, Nick Anas, Keith Meyer, Paul A Checchia, Richard Lin, Thomas P Shanley, Michael T Bigham, Derek S Wheeler, Prasad Devarajan, Stuart L Goldstein and Hector R Wong
    Citation: Critical Care 2011 15:R273
    Content type: Research Published on:

  13. Endotype classification may guide immunomodulatory management of patients with bacterial and viral sepsis. We aimed to identify immune endotypes and...

    Authors: Evdoxia Kyriazopoulou, Yehudit Hasin-Brumshtein, Uros Midic, Garyfallia Poulakou, Haralampos Milionis, Simeon Metallidis, Myrto Astriti, Archontoula Fragkou, Aggeliki Rapti, Eleonora Taddei, Ioannis Kalomenidis, Georgios Chrysos, Andrea Angheben, Ilias Kainis, Zoi Alexiou, Francesco Castelli…
    Citation: Critical Care 2024 28:73
    Content type: Research Published on:

  14. The pathophysiology of sepsis consists of two phases. A first phase...

    Authors: Giovanni Matera, Rossana Puccio, Aida Giancotti, Angela Quirino, Maria Concetta Pulicari, Emilia Zicca, Santo Caroleo, Attilio Renzulli, Maria Carla Liberto and Alfredo Focà
    Citation: Critical Care 2013 17:R64
    Content type: Research Published on:

  16. Procalcitonin (PCT) has been proposed as a marker of infection in critically ill patients; its level is related to the severity of infection. We evaluated the value of PCT as a marker of bacterial infection fo...

    Authors: Yi-Ling Chan, Ching-Ping Tseng, Pei-Kuei Tsay, Shy-Shin Chang, Te-Fa Chiu and Jih-Chang Chen
    Citation: Critical Care 2003 8:R12
    Content type: Research Published on:

  17. Seven hundred and twenty-five of 3,409 patients received artificial nutrition: 303 received total parenteral nutrition (TPN) and 422 received enteral nutrition (EN). Twenty-three percent of patients developed ...

    Authors: Teodoro Grau, Alfonso Bonet, Mercedes Rubio, Dolores Mateo, Mercé Farré, José Antonio Acosta, Antonio Blesa, Juan Carlos Montejo, Abelardo García de Lorenzo and Alfonso Mesejo
    Citation: Critical Care 2007 11:R10
    Content type: Research Published on:

  18. Patients with critical illness can lose more than 15% of muscle mass in one week, and this can have long-term detrimental effects. However, there is currently no synthesis of the data of intensive care unit (I...

    Authors: Brigitta Fazzini, Tobias Märkl, Christos Costas, Manfred Blobner, Stefan J. Schaller, John Prowle, Zudin Puthucheary and Henning Wackerhage
    Citation: Critical Care 2023 27:2
    Content type: Review Published on:

  19. Among 10,941 patients admitted to participating ICUs between October 2009 and September 2011, 1,495 (13.7%) patients presented inclusion criteria for septic shock and were included. Invasive mechanical ventila...

    Authors: Jean-Pierre Quenot, Christine Binquet, Fady Kara, Olivier Martinet, Frederique Ganster, Jean-Christophe Navellou, Vincent Castelain, Damien Barraud, Joel Cousson, Guillaume Louis, Pierre Perez, Khaldoun Kuteifan, Alain Noirot, Julio Badie, Chaouki Mezher, Henry Lessire…
    Citation: Critical Care 2013 17:R65
    Content type: Research Published on:

  20. Extracellular histones have been associated with severity and outcome in sepsis. The aim of the present study was ... polyanion, on the severity and outcome of sepsis in an experimental model.

    Authors: Bruno Garcia, Fuhong Su, Laurence Dewachter, Yong Wang, Ning Li, Myriam Remmelink, Marie Van Eycken, Amina Khaldi, Raphaël Favory, Antoine Herpain, Anthony Moreau, Alexander Moiroux-Sahraoui, Francesca Manicone, Filippo Annoni, Lin Shi, Jean-Louis Vincent…
    Citation: Critical Care 2023 27:458
    Content type: Research Published on:

  21. High-level antibiotic consumption plays a critical role in the selection and spread of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) in the ICU. Implementation of a stewardship program in...

    Authors: Christophe Le Terrier, Marco Vinetti, Paul Bonjean, Régine Richard, Bruno Jarrige, Bertrand Pons, Benjamin Madeux, Pascale Piednoir, Fanny Ardisson, Elain Elie, Frédéric Martino, Marc Valette, Edouard Ollier, Sébastien Breurec, Michel Carles and Guillaume Thiéry
    Citation: Critical Care 2021 25:261
    Content type: Research Published on:

  22. Many critically ill patients develop hemostatic abnormalities, ranging from isolated thrombocytopenia or prolonged global clotting tests to complex defects, such as disseminated intravascular coagulation. Ther...

    Authors: Marcel Levi and Steven M Opal
    Citation: Critical Care 2006 10:222
    Content type: Review Published on:

  23. Recombinant human activated protein C (rhAPC) has been reported to be cost-effective in severely ill septic patients in studies using data from a pivotal randomized trial. We evaluated the cost-effectiveness of r...

    Authors: Jean-François Dhainaut, Stéphanie Payet, Benoit Vallet, Lionel Riou França, Djillali Annane, Pierre-Edouard Bollaert, Yves Le Tulzo, Isabelle Runge, Yannick Malledant, Bertrand Guidet, Katell Le Lay and Robert Launois
    Citation: Critical Care 2007 11:R99
    Content type: Research Published on:

  24. Angiotensin II is one of the vasopressors available for use in septic shock. However, its effects on the septic myocardium remain unclear. The aim of the study was to compare the effects of angiotensin II and ...

    Authors: Bruno Garcia, Fuhong Su, Laurence Dewachter, Raphaël Favory, Amina Khaldi, Alexander Moiroux-Sahraoui, Filippo Annoni, Francisco Vasques-Nóvoa, Estela Rocha-Oliveira, Roberto Roncon-Albuquerque Jr, Geraldine Hubesch, Hassane Njimi, Jean-Louis Vincent, Fabio S. Taccone, Jacques Creteur and Antoine Herpain
    Citation: Critical Care 2022 26:281
    Content type: Research Published on:

  26. It has recently been proposed that B lymphocytes are involved in sepsis pathogenesis. The goal of this study is...

    Authors: Jorge Monserrat, Raul de Pablo, David Diaz-Martín, Manuel Rodríguez-Zapata, Antonio de la Hera, Alfredo Prieto and Melchor Alvarez-Mon
    Citation: Critical Care 2013 17:R105
    Content type: Research Published on:

  27. Alterations in circulating large neutral amino acids (LNAAs), leading to a decrease in the plasma ratio between branched-chain and aromatic amino acids (BCAA/AAA ratio), may be involved in sepsis-associated encep...

    Authors: Ronan MG Berg, Sarah Taudorf, Damian M Bailey, Carsten Lundby, Fin Stolze Larsen, Bente Klarlund Pedersen and Kirsten Møller
    Citation: Critical Care 2010 14:R16
    Content type: Research Published on:

  28. In order to evaluate the complications and risk factors associated with peripheral arterial catheters used for haemodynamic monitoring, we reviewed the literature published from 1978 to 2001. We closely examin...

    Authors: Bernd Volker Scheer, Azriel Perel and Ulrich J Pfeiffer
    Citation: Critical Care 2002 6:199
    Content type: Review Published on:

  29. Critical care medicine is a relatively young but rapidly evolving specialty. On the occasion of the 30th International Symposium on Intensive Care and Emergency Medicine, we put together some thoughts from a f...

    Authors: Jean-Louis Vincent, Mervyn Singer, John J Marini, Rui Moreno, Mitchell Levy, Michael A Matthay, Michael Pinsky, Andrew Rhodes, Niall D Ferguson, Timothy Evans, Djillali Annane and Jesse B Hall
    Citation: Critical Care 2010 14:311
    Content type: Viewpoint Published on:

  30. Streptococcus (S.) pneumoniae...is the most common cause of community-acquired pneumonia. The factor V Leiden (FVL) mutation results in resistance of activated FV to inactivation by activated protein C and thereb...

    Authors: Marcel Schouten, Cornelis van't Veer, Joris JTH Roelofs, Marcel Levi and Tom van der Poll
    Citation: Critical Care 2010 14:R145
    Content type: Research Published on:

  33. Patients with low (<250 nM) Δ cortisol (n = 14 to 17) had higher baseline cortisol and ACTH but lower cortisol/ACTH ratios than patients with a normal Δ cortisol (≥250 nM...) in the course of time. A low Δ cortis...

    Authors: Margriet FC de Jong, Nienke Molenaar, Albertus Beishuizen and AB Johan Groeneveld
    Citation: Critical Care 2015 19:1
    Content type: Research Published on:

    The Erratum to this article has been published in Critical Care 2015 19:313

  36. We retrieved 555 charts; 47 unexpected deaths were analysed; 24 (51%) were considered as preventable. There was a median number of medical errors of two. The most common process breakdowns were incorrect choice o...

    Authors: Hélène Goulet, Victor Guerand, Benjamin Bloom, Patricia Martel, Philippe Aegerter, Enrique Casalino, Bruno Riou and Yonathan Freund
    Citation: Critical Care 2015 19:154
    Content type: Research Published on:

  39. We studied a cohort of adult critically ill patients requiring invasive mechanical ventilation and treatment with continuous infusion of cisatracurium for at least 12 h. The study aimed to quantify the effect ...

    Authors: W. A. C. Koekkoek, Y. A. Menger, F. J. L. van Zanten, D. van Dijk and A. R. H. van Zanten
    Citation: Critical Care 2020 24:32
    Content type: Research Published on:

  40. With advances in the treatment of sepsis, the systemic inflammatory response syndrome (SIRS) ... is no longer used for the diagnosis of sepsis, the disseminated intravascular coagulation (DIC) diagnostic...

    Authors: Toshiaki Iba, Marcello Di Nisio, Jecko Thachil, Hideo Wada, Hidesaku Asakura, Koichi Sato, Naoya Kitamura and Daizoh Saitoh
    Citation: Critical Care 2016 20:287
    Content type: Research Published on:

  41. The fast-acting β-1 blocker esmolol has been the center of attention since the landmark article by Morrelli and colleagues suggesting that, in patients with sepsis, reducing heart rate by administering esmolol ca...

    Authors: Can Ince
    Citation: Critical Care 2015 19:339
    Content type: Commentary Published on:

  42. We performed a metabolomic study with biorepository plasma samples collected from 73 adults with systemic inflammatory response syndrome or sepsis at a single academic medical center. Patients...p values to evalu...

    Authors: Pär I. Johansson, Kiichi Nakahira, Angela J. Rogers, Michael J. McGeachie, Rebecca M. Baron, Laura E. Fredenburgh, John Harrington, Augustine M. K. Choi and Kenneth B. Christopher
    Citation: Critical Care 2018 22:360
    Content type: Research Published on:

  43. Patients with severe malaria (n=138), uncomplicated malaria (n=102), sepsis (n=32) and febrile encephalopathy (n ... .2 mEq/L±4.5) and severe sepsis (8.6 mEq/L±7.7)...P<0.05). In urine, concentrations of methylma...

    Authors: M. Trent Herdman, Natthida Sriboonvorakul, Stije J. Leopold, Sam Douthwaite, Sanjib Mohanty, M. Mahtab Uddin Hassan, Richard J. Maude, Hugh WF Kingston, Katherine Plewes, Prakaykaew Charunwatthana, Kamolrat Silamut, Charles J. Woodrow, Kesinee Chotinavich, Md. Amir Hossain, M. Abul Faiz, Saroj Mishra…
    Citation: Critical Care 2015 19:317
    Content type: Research Published on:

    The Erratum to this article has been published in Critical Care 2015 19:382

  44. This study investigated changes in plasma level of soluble endothelial protein C receptor (sEPCR) in association with outcome in patients with septic shock. We explored sEPCR for early sepsis prognosis assessment...

    Authors: Agnès Chapelet, Yohann Foucher, Nathalie Gérard, Christophe Rousseau, Olivier Zambon, Cédric Bretonnière, Jean-Paul Mira, Béatrice Charreau and Christophe Guitton
    Citation: Critical Care 2018 22:251
    Content type: Research Published on:

  45. We performed a single-center, prospective cohort study among 121 critically ill patients admitted to intensive care units (ICUs) between 2008 and 2012. We measured plasma hCAP18, 25D, D-binding protein, and parat...

    Authors: David E Leaf, Heather E Croy, Sara J Abrahams, Anas Raed and Sushrut S Waikar
    Citation: Critical Care 2015 19:80
    Content type: Research Published on:

  46. Chemokine (C-X3-C motif) receptor 1 (CX3CR1) was identified as the most differentially expressed gene between survivors and non-survivors in two independent cohorts of septic shock patients and was proposed as a ...

    Authors: Arnaud Friggeri, Marie-Angélique Cazalis, Alexandre Pachot, Martin Cour, Laurent Argaud, Bernard Allaouchiche, Bernard Floccard, Zoé Schmitt, Olivier Martin, Thomas Rimmelé, Oriane Fontaine-Kesteloot, Mathieu Page, Vincent Piriou, Julien Bohé, Guillaume Monneret, Stéphane Morisset…
    Citation: Critical Care 2016 20:204
    Content type: Research Published on:

  47. Rapid detection, early resuscitation, and appropriate antibiotic use are crucial for sepsis care. Accurate identification of the site of...

    Authors: Toshikazu Abe, Yasuharu Tokuda, Atsushi Shiraishi, Seitaro Fujishima, Toshihiko Mayumi, Takehiro Sugiyama, Gautam A. Deshpande, Yasukazu Shiino, Toru Hifumi, Yasuhiro Otomo, Kohji Okamoto, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-ichiro Shiraishi, Kiyotsugu Takuma…
    Citation: Critical Care 2019 23:202
    Content type: Research Published on:

    The Letter to this article has been published in Critical Care 2019 23:294

  48. A total of 337 patients with sepsis requiring VP support for at least 6...n = 93) patients were 1:1 propensity matched to D-VPs (n = 93) based on age; source of admission (emergency room, general wards, intensive...

    Authors: Gustavo A. Ospina-Tascón, Glenn Hernandez, Ingrid Alvarez, Luis E. Calderón-Tapia, Ramiro Manzano-Nunez, Alvaro I. Sánchez-Ortiz, Egardo Quiñones, Juan E. Ruiz-Yucuma, José L. Aldana, Jean-Louis Teboul, Alexandre Biasi Cavalcanti, Daniel De Backer and Jan Bakker
    Citation: Critical Care 2020 24:52
    Content type: Research Published on:

  49. Cell-free plasma hemoglobin is associated with poor outcome in patients with sepsis. Extracellular hemoglobin and secondarily released heme amplify...

    Authors: Tian Lin, Dayana Maita, Sujatha R Thundivalappil, Frank E Riley, Jasmin Hambsch, Linda J Van Marter, Helen A Christou, Lorenzo Berra, Shawn Fagan, David C Christiani and H Shaw Warren
    Citation: Critical Care 2015 19:166
    Content type: Research Published on:

  50. Acute kidney injury (AKI) is a multifactorial syndrome, but knowledge about its pathophysiology and possible genetic background is limited. Recently the first hypothesis-free genetic association studies have b...

    Authors: Laura M. Vilander, Mari A. Kaunisto, Suvi T. Vaara and Ville Pettilä
    Citation: Critical Care 2017 21:47
    Content type: Research Published on:

    The Editorial to this article has been published in Critical Care 2017 21:138

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Critical Care

ISSN: 1364-8535