Open Access

Erratum to: Diminished adrenal sensitivity to endogenous and exogenous adrenocorticotropic hormone in critical illness: a prospective cohort study

  • Margriet FC de Jong1Email author,
  • Nienke Molenaar2,
  • Albertus Beishuizen3, 4 and
  • AB Johan Groeneveld5
Critical Care201519:313

https://doi.org/10.1186/s13054-015-1015-5

Published: 4 September 2015

The original article was published in Critical Care 2015 19:1

Unfortunately, the original version of this article [1] contained an error. Table Two (Table 1 here) was included incorrectly. The correct Table Two (Table 1 here) can be found below:
Table 1

ACTH Test 1 and 2 classified according to groups of Δ cortisol <, ≥ 250 nmol/L

 

Test 1 Δ<250 nmol/L

Test 1 Δ≥250 nmol/L

Test 2 Δ<250 nmol/L

Test 2 Δ≥250 nmol/L

P Δ cortisol, time, interaction

n=17

n=42

n=14

n=45

ACTH, pmol/L

3.1 (1.1–18.0)

1.5 (1.1–15.0)

6.0 (1.1–14.0)

3.8 (1.0–8.9)

0.001, 0.025, 0.72

Baseline cortisol, nmol/L

470 (200–1355)

430 (75–2670)

655 (335–1890)

495 (35–2670)

0.021, 0.12, 0.30

Baseline cortisol/ACTH, nmol/pmol

148 (36–250)

238 (14–2054)

109 (48–1718)

126 (35–2054)

0.029, 0.16, 0.14

Baseline free cortisol, nmol/L

77 (63–357) (n=9)

86 (38–256) (n=14)

154 (114–252) (n=6)

75 (4–151) (n=20)

0.001, 0.91, 0.19

Baseline free cortisol/ACTH, nmol/pmol

22 (9–38)

39 (16–89)

26 (11–43)

17 (4–35)

0.042, 0.10, <0.001

Δ cortisol, nmol/L

140 (−50–245)

388 (260–4015)

177 (−80–230)

425 (255–965)

n.a., 0.45, 0.093

Δ free cortisol, nmol/L

59 (−71–124)

151 (74–678)

40 (−34–99)

133 (32–233)

<0.001, 0.15, 0.16

CBG, mg/L

23 (6–43)

29 (13–63)

39 (4–60)

41 (21–65)

0.060, <0.001, 0.90

Albumin, g/L

13 (6–32)

17 (6–24)

16 (12–28)

20 (8–32)

0.25, <0.001, 0.89

Days from admission - test

1 (0–50)

3 (0–44)

25 (9–49)

20 (9–83)

0.57*, 0.15*

Days between tests

n.a.

n.a.

18 (8–34)

16 (8–43)

0.41*

Days after stop hydrocortisone

n.a.

n.a.

7 (5–12)

7 (5–14)

0.75*

Median (range); ACTH: adrenocorticotropic hormone, CBG: cortisol binding globulin. *Mann–Whitney U test, otherwise generalized estimating equations; n.a.: not applicable

Notes

Declarations

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
Department of Nephrology, VU University Medical Centre
(2)
Department of Surgery, University Medical Centre Groningen
(3)
Department of Intensive Care, Medical Spectrum Twente
(4)
Department of Intensive Care, VU University Medical Centre
(5)
Department of Intensive Care, Erasmus Medical Centre

Reference

  1. de Jong MF, Molenaar N, Beishuizen A, Groeneveld AB. Diminished adrenal sensitivity to endogenous and exogenous adrenocorticotropic hormone in critical illness: a prospective cohort study. Critical Care. 2015;19:1.View ArticlePubMedPubMed CentralGoogle Scholar

Copyright

© de Jong et al. 2015

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