Articles
Page 33 of 375
-
Citation: Critical Care 2021 25:1
-
Plasma levels of the active form of suPAR are associated with COVID-19 severity
Citation: Critical Care 2020 24:704 -
The fluid challenge
Citation: Critical Care 2020 24:703 -
Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): international expert consensus
COVID-19 has caused great devastation in the past year. Multi-organ point-of-care ultrasound (PoCUS) including lung ultrasound (LUS) and focused cardiac ultrasound (FoCUS) as a clinical adjunct has played a si...
Citation: Critical Care 2020 24:702 -
Prognostic value of bedside lung ultrasound score in patients with COVID-19
Bedside lung ultrasound (LUS) has emerged as a useful and non-invasive tool to detect lung involvement and monitor changes in patients with coronavirus disease 2019 (COVID-19). However, the clinical significan...
Citation: Critical Care 2020 24:700 -
Risks of ventilator-associated pneumonia and invasive pulmonary aspergillosis in patients with viral acute respiratory distress syndrome related or not to Coronavirus 19 disease
Data on incidence of ventilator-associated pneumonia (VAP) and invasive pulmonary aspergillosis in patients with severe SARS-CoV-2 infection are limited.
Citation: Critical Care 2020 24:699 -
Corticosteroid therapy in critically ill patients with COVID-19: a multicenter, retrospective study
Corticoid therapy has been recommended in the treatment of critically ill patients with COVID-19, yet its efficacy is currently still under evaluation. We investigated the effect of corticosteroid treatment on...
Citation: Critical Care 2020 24:698 -
Lower versus higher hemoglobin threshold for transfusion in ARDS patients with and without ECMO
Efficacy and safety of different hemoglobin thresholds for transfusion of red blood cells (RBCs) in adults with an acute respiratory distress syndrome (ARDS) are unknown. We therefore assessed the effect of tw...
Citation: Critical Care 2020 24:697 -
Corticosteroid use in COVID-19 patients: a systematic review and meta-analysis on clinical outcomes
In the current SARS-CoV-2 pandemic, there has been worldwide debate on the use of corticosteroids in COVID-19. In the recent RECOVERY trial, evaluating the effect of dexamethasone, a reduced 28-day mortality i...
Citation: Critical Care 2020 24:696 -
Getting out of the 1950s: rethinking old priorities for staffing in critical care
Citation: Critical Care 2020 24:695 -
Local signs at insertion site and catheter-related bloodstream infections: an observational post hoc analysis using individual data of four RCTs
Little is known on the association between local signs and intravascular catheter infections. This study aimed to evaluate the association between local signs at removal and catheter-related bloodstream infect...
Citation: Critical Care 2020 24:694 -
Resuscitation fluid types in sepsis, surgical, and trauma patients: a systematic review and sequential network meta-analyses
Crystalloids and different component colloids, used for volume resuscitation, are sometimes associated with various adverse effects. Clinical trial findings for such fluid types in different patients’ conditio...
Citation: Critical Care 2020 24:693 -
High flow nasal therapy versus noninvasive ventilation as initial ventilatory strategy in COPD exacerbation: a multicenter non-inferiority randomized trial
The efficacy and safety of high flow nasal therapy (HFNT) in patients with acute hypercapnic exacerbation of chronic obstructive pulmonary disease (AECOPD) are unclear. Our aim was to evaluate the short-term e...
Citation: Critical Care 2020 24:692 -
Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19
COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-2 RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID-19 is characterized by a dysregulated host re...
Citation: Critical Care 2020 24:691 -
Incidence rate and clinical impacts of arrhythmia following COVID-19: a systematic review and meta-analysis of 17,435 patients
Citation: Critical Care 2020 24:690 -
Machine learning to predict hemorrhage and thrombosis during extracorporeal membrane oxygenation
Citation: Critical Care 2020 24:689 -
Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study
A subset of critically ill COVID-19 patients develop a hyperinflammatory state. Anakinra, a recombinant interleukin-1 receptor antagonist, is known to be effective in several hyperinflammatory diseases. We inv...
Citation: Critical Care 2020 24:688 -
Chlorhexidine-dress related contact dermatitis—the precautionary principle is no more relevant!
Citation: Critical Care 2020 24:687 -
A manifesto for the future of ICU trials
Citation: Critical Care 2020 24:686 -
Risk factors and events in the adult intensive care unit associated with pain as self-reported at the end of the intensive care unit stay
The short-term and long-term consequences of the most frequent painful procedures performed in the ICU are unclear. This study aimed to identify the risk factors associated with pain-related discomfort perceiv...
Citation: Critical Care 2020 24:685 -
Role of extracorporeal membrane oxygenation in children with sepsis: a systematic review and meta-analysis
The benefits of extracorporeal membrane oxygenation (ECMO) in children with sepsis remain controversial. Current guidelines on management of septic shock in children recommend consideration of ECMO as salvage ...
Citation: Critical Care 2020 24:684 -
Response to "optic nerve sheath diameter guided detection of sepsis associated encephalopathy"
Citation: Critical Care 2020 24:683 -
Postoperative hypotension in patients discharged to the intensive care unit after non-cardiac surgery is associated with adverse clinical outcomes
The postoperative period is critical for a patient’s recovery, and postoperative hypotension, specifically, is associated with adverse clinical outcomes and significant harm to the patient. However, little is ...
Citation: Critical Care 2020 24:682 -
Peripheral blood transcriptomic sub-phenotypes of pediatric acute respiratory distress syndrome
Acute respiratory distress syndrome (ARDS) is heterogeneous and may be amenable to sub-phenotyping to improve enrichment for trials. We aimed to identify subtypes of pediatric ARDS based on whole blood transcr...
Citation: Critical Care 2020 24:681 -
Standardized visual EEG features predict outcome in patients with acute consciousness impairment of various etiologies
Early prognostication in patients with acute consciousness impairment is a challenging but essential task. Current prognostic guidelines vary with the underlying etiology. In particular, electroencephalography...
Citation: Critical Care 2020 24:680 -
Transesophageal echocardiography-associated tracheal microaspiration and ventilator-associated pneumonia in intubated critically ill patients: a multicenter prospective observational study
Microaspiration of gastric and oropharyngeal secretions is the main causative mechanism of ventilator-associated pneumonia (VAP). Transesophageal echocardiography (TEE) is a routine investigation tool in inten...
Citation: Critical Care 2020 24:679 -
Electrical impedance tomography to titrate positive end-expiratory pressure in COVID-19 acute respiratory distress syndrome
Patients with coronavirus disease-19-related acute respiratory distress syndrome (C-ARDS) could have a specific physiological phenotype as compared with those affected by ARDS from other causes (NC-ARDS).
Citation: Critical Care 2020 24:678 -
The Adaptive COVID-19 Treatment Trial-1 (ACTT-1) in a real-world population: a comparative observational study
Citation: Critical Care 2020 24:677 -
Thromboembolic complications in critically ill COVID-19 patients are associated with impaired fibrinolysis
There is emerging evidence for enhanced blood coagulation in coronavirus 2019 (COVID-19) patients, with thromboembolic complications contributing to morbidity and mortality. The mechanisms underlying this prot...
Citation: Critical Care 2020 24:676 -
Correction to: Effect of PEEP decremental on respiratory mechanics, gas exchange, pulmonary regional ventilation, and hemodynamics in patients with SARS-Cov-2-associated Acute Respiratory Distress Syndrome
An amendment to this paper has been published and can be accessed via the original article.
Citation: Critical Care 2020 24:675 -
Percutaneous right ventricular assist device, rapid employment in right ventricular failure during septic shock
Citation: Critical Care 2020 24:674 -
The future of AI in critical care is augmented, not artificial, intelligence
Citation: Critical Care 2020 24:673 -
Impact of advance directives on the variability between intensivists in the decisions to forgo life-sustaining treatment
There is wide variability between intensivists in the decisions to forgo life-sustaining treatment (DFLST). Advance directives (ADs) allow patients to communicate their end-of-life wishes to physicians. We ass...
Citation: Critical Care 2020 24:672 -
How I approach membrane lung dysfunction in patients receiving ECMO
Citation: Critical Care 2020 24:671 -
Right ventricular-arterial uncoupling independently predicts survival in COVID-19 ARDS
To investigate the prevalence and prognostic impact of right heart failure and right ventricular-arterial uncoupling in Corona Virus Infectious Disease 2019 (COVID-19) complicated by an Acute Respiratory Distr...
Citation: Critical Care 2020 24:670 -
Ultrasound shear wave elastography for assessing diaphragm function in mechanically ventilated patients: a breath-by-breath analysis
Diaphragm dysfunction is highly prevalent in mechanically ventilated patients. Recent work showed that changes in diaphragm shear modulus (ΔSMdi) assessed using ultrasound shear wave elastography (SWE) are str...
Citation: Critical Care 2020 24:669 -
VICINO@TE, distant but together, new app to communicate with families living in complete isolation during COVID-19 pandemic
Citation: Critical Care 2020 24:668 -
Xenon treatment after severe traumatic brain injury improves locomotor outcome, reduces acute neuronal loss and enhances early beneficial neuroinflammation: a randomized, blinded, controlled animal study
Traumatic brain injury (TBI) is a major cause of morbidity and mortality, but there are no clinically proven treatments that specifically target neuronal loss and secondary injury development following TBI. In...
Citation: Critical Care 2020 24:667 -
Severe manifestations of SARS-CoV-2 in children and adolescents: from COVID-19 pneumonia to multisystem inflammatory syndrome: a multicentre study in pediatric intensive care units in Spain
Multisystem inflammatory syndrome temporally associated with COVID-19 (MIS-C) has been described as a novel and often severe presentation of SARS-CoV-2 infection in children. We aimed to describe the character...
Citation: Critical Care 2020 24:666 -
Correction to: Inhaled nitric oxide in patients admitted to intensive care unit with COVID-19 pneumonia
An amendment to this paper has been published and can be accessed via the original article.
Citation: Critical Care 2020 24:665 -
Antibiotic therapeutic drug monitoring in intensive care patients treated with different modalities of extracorporeal membrane oxygenation (ECMO) and renal replacement therapy: a prospective, observational single-center study
Effective antimicrobial treatment is key to reduce mortality associated with bacterial sepsis in patients on intensive care units (ICUs). Dose adjustments are often necessary to account for pathophysiological ...
Citation: Critical Care 2020 24:664 -
Influence of the acuity of patients’ illness on effectiveness of early, goal-directed mobilization in the intensive care unit: a post hoc analysis
Citation: Critical Care 2020 24:663 -
Individualized flow-controlled ventilation compared to best clinical practice pressure-controlled ventilation: a prospective randomized porcine study
Flow-controlled ventilation is a novel ventilation method which allows to individualize ventilation according to dynamic lung mechanic limits based on direct tracheal pressure measurement at a stable constant ...
Citation: Critical Care 2020 24:662 -
Prediction of hypotension events with physiologic vital sign signatures in the intensive care unit
Even brief hypotension is associated with increased morbidity and mortality. We developed a machine learning model to predict the initial hypotension event among intensive care unit (ICU) patients and designed...
Citation: Critical Care 2020 24:661 -
Correction to: Substrate utilization and energy expenditure pattern in sepsis by indirect calorimetry
An amendment to this paper has been published and can be accessed via the original article.
Citation: Critical Care 2020 24:660 -
High-flow nasal cannula can’t be considered non-inferior to noninvasive ventilation in patients with chronic obstructive pulmonary disease who develop respiratory failure after extubation
Citation: Critical Care 2020 24:659 -
SARS-CoV-2-associated encephalitis: arguments for a post-infectious mechanism
Citation: Critical Care 2020 24:658 -
Correlation of interleukin-6 with Epstein–Barr virus levels in COVID-19
Citation: Critical Care 2020 24:657 -
Open-chest versus closed-chest cardiopulmonary resuscitation in trauma patients: effect size is probably higher for penetrating injury
Citation: Critical Care 2020 24:655 -
Nasal high flow higher than 60 L/min in patients with acute hypoxemic respiratory failure: a physiological study
Nasal high flow delivered at flow rates higher than 60 L/min in patients with acute hypoxemic respiratory failure might be associated with improved physiological effects. However, poor comfort might limit feas...
Citation: Critical Care 2020 24:654
Follow
- ISSN: 1364-8535 (electronic)