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  1. Transfusable fluids that may be used as alternatives to red blood cell transfusion offer the promise of preserving tissue perfusion and minimizing hypoxic cellular damage, and this promise may soon be fulfille...

    Authors: A Gerson Greenburg and Hae Won Kim
    Citation: Critical Care 2004 8(Suppl 2):S61
    Content type: Review Published on:

    This article is part of a Supplement: Volume 8 Supplement 2

  2. Although preoperative autologous blood donation is employed in elective surgery, this is declining because of the increasingly safe allogeneic blood supply. However, it continues to be used because of the publ...

    Authors: Lawrence T Goodnough
    Citation: Critical Care 2004 8(Suppl 2):S49
    Content type: Review Published on:

    This article is part of a Supplement: Volume 8 Supplement 2

  4. Tracheotomy is widely performed in the intensive care unit after long-term oral intubation. The present study investigates the immediate influence of tracheotomy on respiratory mechanics and blood gases during...

    Authors: Argyro Amygdalou, George Dimopoulos, Markos Moukas, Christos Katsanos, Athina Katagi, Costas Mandragos, Stavros H Constantopoulos, Panagiotis K Behrakis and Miltos P Vassiliou
    Citation: Critical Care 2004 8:R243
    Content type: Research Published on:

  5. Both C-reactive protein (CRP) and procalcitonin (PCT) are accepted sepsis markers. However, there is still some debate concerning the correlation between their serum concentrations and sepsis severity. We hypo...

    Authors: Gian Paolo Castelli, Claudio Pognani, Michael Meisner, Antonio Stuani, Daniela Bellomi and Laura Sgarbi
    Citation: Critical Care 2004 8:R234
    Content type: Research Published on:

  7. Large quantitaties of inflammatory mediators are released during the course of endotoxaemia. These mediators in turn can stimulate the sympathetic nervous system (SNS) to release catecholamines, which ultimate...

    Authors: Grietje Ch Beck, Paul Brinkkoetter, Christine Hanusch, Jutta Schulte, Klaus van Ackern, Fokko J van der Woude and Benito A Yard
    Citation: Critical Care 2004 8:485
    Content type: Review Published on:

  12. The importance of accidental catheter removal (ACR) lies in the complications caused by the removal itself and by catheter reinsertion. To the best of our knowledge, no studies have analyzed accidental removal...

    Authors: Leonardo Lorente, María S Huidobro, María M Martín, Alejandro Jiménez and María L Mora
    Citation: Critical Care 2004 8:R229
    Content type: Research Published on:

  14. We conducted the present study to investigate whether early large-volume crystalloid infusion can restore gut mucosal blood flow and mesenteric oxygen metabolism in severe sepsis.

    Authors: Claudio Esteves Lagoa, Luiz FranciscoPoli de Figueiredo, Ruy Jorge Cruz Jr, Eliézer Silva and Maurício Rocha e Silva
    Citation: Critical Care 2004 8:R221
    Content type: Research Published on:

  15. It is recognized that administration of insulin with glucose decreases catabolic response in sepsis. The aim of the present study was to compare the effects of two levels of insulinaemia on glucose metabolism ...

    Authors: Zdenek Rusavy, Vladimir Sramek, Silvie Lacigova, Ivan Novak, Pavel Tesinsky and Ian A Macdonald
    Citation: Critical Care 2004 8:R213
    Content type: Research Published on:

  17. Acute lung injury (ALI) and the acute respiratory distress syndrome are complex syndromes because both inflammatory and coagulation cascades cause lung injury. Transport of salt and water, repair and remodelin...

    Authors: Horacio E Groshaus, Sanjay Manocha, Keith R Walley and James A Russell
    Citation: Critical Care 2004 8:234
    Content type: Review Published on:

  18. Rusavy and colleagues recently endeavoured to dissect out the metabolic effects of insulin in patients with severe sepsis, in the setting of normoglycaemia. Twenty stable patients were studied 3–7 days after a...

    Authors: Simon J Finney
    Citation: Critical Care 2004 8:227
    Content type: Commentary Published on:

  19. There is no consensus definition of acute renal failure (ARF) in critically ill patients. More than 30 different definitions have been used in the literature, creating much confusion and making comparisons dif...

    Authors: Rinaldo Bellomo, Claudio Ronco, John A Kellum, Ravindra L Mehta and Paul Palevsky
    Citation: Critical Care 2004 8:R204
    Content type: Research Published on:

  20. The aim of this study was to evaluate the performance of five general severity-of-illness scores (Acute Physiology and Chronic Health Evaluation II and III-J, the Simplified Acute Physiology Score II, and the ...

    Authors: Márcio Soares, Flávia Fontes, Joana Dantas, Daniela Gadelha, Paloma Cariello, Flávia Nardes, César Amorim, Luisa Toscano and José R Rocco
    Citation: Critical Care 2004 8:R194
    Content type: Research Published on:

  22. Two generic paediatric mortality scoring systems have been validated in the paediatric intensive care unit (PICU). Paediatric RISk of Mortality (PRISM) requires an observation period of 24 hours, and PRISM III...

    Authors: Stéphane Leteurtre, Francis Leclerc, Jessica Wirth, Odile Noizet, Eric Magnenant, Ahmed Sadik, Catherine Fourier and Robin Cremer
    Citation: Critical Care 2004 8:R185
    Content type: Research Published on:

  23. Sepsis and severe sepsis are asociated with high hospital mortality. Little is known about the occurrence of sepsis in general hospital populations. The goal of the present study was to reveal the epidemiology...

    Authors: Hans Flaatten
    Citation: Critical Care 2004 8:R180
    Content type: Research Published on:

  24. The purpose of the present study was to evaluate the effects of continuously infused N-acetyl-L-cystein (NAC) on serum cytokine levels and gastric intramucosal pH in humans suffering from severe sepsis.

    Authors: Sayım Emet, Dilek Memiş and Zafer Pamukçu
    Citation: Critical Care 2004 8:R172
    Content type: Research Published on:

    The Erratum to this article has been published in Critical Care 2016 20:403

  25. The role played by several vasoactive mediators that are synthesized and released by the pulmonary vascular endothelium in the regulation of hypoxic pulmonary vasoconstriction (HPV) remains unclear. As a poten...

    Authors: Ives Hubloue, Benoît Rondelet, François Kerbaul, Dominique Biarent, Guiti Malekzadeh Milani, Michel Staroukine, Pierre Bergmann, Robert Naeije and Marc Leeman
    Citation: Critical Care 2004 8:R163
    Content type: Research Published on:

  27. Critically ill patients frequently develop anemia due to several factors. Iron-withholding mechanisms caused by inflammation contribute to this anemia. The iron metabolism imbalances described or reported in a...

    Authors: Martin Darveau, André Y Denault, Normand Blais and Éric Notebaert
    Citation: Critical Care 2004 8:356
    Content type: Review Published on:

  28. Most clinical trials on the topic of extubation have involved patients outside the neurological intensive care unit. As a result, in this area clinicians are left with little evidence on which to base their de...

    Authors: Luciana Mascia, Eleomore Corno, Pier Paok Terragni, David Stather and Niall D Ferguson
    Citation: Critical Care 2004 8:327
    Content type: Review Published on:

  29. The importance of chest wall elastance in characterizing acute lung injury/acute respiratory distress syndrome patients and in setting mechanical ventilation is increasingly recognized. Nearly 30% of patients ...

    Authors: Luciano Gattinoni, Davide Chiumello, Eleondra Carlesso and Franco Valenza
    Citation: Critical Care 2004 8:350
    Content type: Review Published on:

  31. Outside the intensive care unit (ICU), clinically important deep vein thrombosis (DVT) is usually defined as a symptomatic event that leads to objective radiologic confirmation and subsequent treatment. The ob...

    Authors: Deborah Cook, Maureen Meade, Gordon Guyatt, Lauren Griffith, John Granton, William Geerts and Mark Crowther
    Citation: Critical Care 2004 8:R145
    Content type: Research Published on:

  37. This review introduces nonparametric methods for testing differences between more than two groups or treatments. Three of the more common tests are described in detail, together with multiple comparison proced...

    Authors: Viv Bewick, Liz Cheek and Jonathan Ball
    Citation: Critical Care 2004 8:196
    Content type: Review Published on:

  38. This review addresses the pathophysiology and treatment of hemorrhagic shock – a condition produced by rapid and significant loss of intravascular volume, which may lead sequentially to hemodynamic instability...

    Authors: Guillermo Gutierrez, HDavid Reines and Marian E Wulf-Gutierrez
    Citation: Critical Care 2004 8:373
    Content type: Review Published on:

  40. The pathogenicity of late respiratory infections with herpes simplex virus type 1 (HSV-1) in the critically ill is unclear.

    Authors: Joanne Verheij, AB Johan Groeneveld, Albertus Beishuizen, Arthur van Lingen, Alberdina M Simoons-Smit and Rob JM Strack van Schijndel
    Citation: Critical Care 2004 8:R139
    Content type: Research Published on:

  41. Purple urine bag syndrome (PUBS) was first reported in 1978. PUBS is rare, occurs predominantly in constipated women, chronically catheterized and associated with some bacterial urinary infections that produce...

    Authors: Joaquim Palmeiro Ribeiro, Paulo Marcelino, Susan Marum, Ana Paula Fernandes and Ana Grilo
    Citation: Critical Care 2004 8:R137
    Content type: Research Published on:

  44. Resuscitation with saline is a standard initial response to hypotension or shock of almost any cause. Saline resuscitation is thought to generate an increase in cardiac output through a preload-dependent (incr...

    Authors: Anand Kumar, Ramon Anel, Eugene Bunnell, Sergio Zanotti, Kalim Habet, Cameron Haery, Stephanie Marshall, Mary Cheang, Alex Neumann, Amjad Ali, Clifford Kavinsky and Joseph E Parrillo
    Citation: Critical Care 2004 8:R128
    Content type: Research Published on:
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Critical Care

ISSN: 1364-8535