Assessment of blood flow during extra-corporeal circulation from arterial waveform analysis
© BioMed Central Ltd. 2004
Published: 15 March 2004
The pressure recording analytical method (PRAM) is a recently developed method for beat-to-beat quantification of cardiac output (CO) based on the analysis of the arterial waveform. Since PRAM can be implemented in various conditions of flow, we assessed its accuracy in cardiac surgery during extra-corporeal circulation (ECC), using the roller pump device (RP) as the reference gold standard.
In 25 patients undergoing cardiac surgery, CO values obtained by the PRAM from the radial artery were compared with bolus thermodilution (TD) before and after ECC, and with the RP readings during ECC before and after aortic clamp. PRAM flow measurements during ECC were based on the analysis of each sinusoidal arterial waveform (the continuous component of flow) produced by the RP.
The PRAM provided accurate and continuous quantification of flow during each phase of cardiac surgery. This new method may allow early recognition of low CO during weaning from ECC.