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6922 result(s) for 'sepsis' within Critical Care

Page 56 of 139

  1. Previous human studies have shown low activity of protein C (APC) in severe acute pancreatitis (SAP). This, together with the findings in animal models, suggests that activated protein C (APC) may protect agai...

    Authors: Ville Pettilä, Lea Kyhälä, Marja-Leena Kylänpää, Ari Leppäniemi, Minna Tallgren, Antti Markkola, Pauli Puolakkainen, Heikki Repo and Esko Kemppainen
    Citation: Critical Care 2010 14:R139
  2. Critical illness polyneuropathy (CIP) and myopathy (CIM) are major complications of severe critical illness and its management. CIP/CIM prolongs weaning from mechanical ventilation and physical rehabilitation sin...

    Authors: Greet Hermans, Bernard De Jonghe, Frans Bruyninckx and Greet Van den Berghe
    Citation: Critical Care 2008 12:238
  3. The effect of hyperglycaemia on the brain cells of septic shock patients is unknown. The objective of this study was to evaluate the relationship between hyperglycaemia and apoptosis in the brains of septic sh...

    Authors: Andrea Polito, Jean-Philippe Brouland, Raphael Porcher, Romain Sonneville, Shidasp Siami, Robert D Stevens, Céline Guidoux, Virginie Maxime, Geoffroy Lorin de la Grandmaison, Fabrice C Chrétien, Françoise Gray, Djillali Annane and Tarek Sharshar
    Citation: Critical Care 2011 15:R131
  4. Acute kidney injury (AKI) is a frequently encountered syndrome especially among the critically ill. Current diagnosis of AKI is based on acute deterioration of kidney function, indicated by an increase in crea...

    Authors: Suvi T. Vaara, Pavan K. Bhatraju, Natalja L. Stanski, Blaithin A. McMahon, Kathleen Liu, Michael Joannidis and Sean M. Bagshaw
    Citation: Critical Care 2022 26:251
  5. Thirteen articles met the inclusion criteria, of which eight articles examined risk factors, four developed a risk prediction model or clinical decision rule and one evaluated a clinical decision rule. Studies va...

    Authors: Hannah Muskett, Jason Shahin, Gavin Eyres, Sheila Harvey, Kathy Rowan and David Harrison
    Citation: Critical Care 2011 15:R287
  6. This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2018. Other selected articles can be found online at

    Authors: Anna Hall, Laurence W. Busse and Marlies Ostermann
    Citation: Critical Care 2018 22:69
  7. Mechanical ventilation and the effect of respiratory muscle unloading on the diaphragm cause ventilator-induced diaphragmatic dysfunction (VIDD). Atrophy of the diaphragmatic muscle is a major part of VIDD, an...

    Authors: Tom Schepens, Walter Verbrugghe, Karolien Dams, Bob Corthouts, Paul M. Parizel and Philippe G. Jorens
    Citation: Critical Care 2015 19:422
  8. This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2018. Other selected articles can be found online at

    Authors: Nora Suzanne Wolff, Floor Hugenholtz and Willem Joost Wiersinga
    Citation: Critical Care 2018 22:78
  9. Septic shock definitions are being revisited. We assess the feasibility, reliability, and validity characteristics of the current definitions and criteria of septic shock. Septic shock is conceptualised as cardio...

    Authors: Manu Shankar-Hari, Guido Bertolini, Frank M. Brunkhorst, Rinaldo Bellomo, Djillali Annane, Clifford S. Deutschman and Mervyn Singer
    Citation: Critical Care 2015 19:445
  10. Of 138 patients included, 73 (53%) had AKI and 40 (29%) required acute RRT. Patients with AKI were significantly older, more likely to have sepsis and had higher APACHE II and SOFA...

    Authors: Ryan Haines, Siobhan Crichton, Jessica Wilson, David Treacher and Marlies Ostermann
    Citation: Critical Care 2017 21:88
  11. Gradual reduction of the dosage of norepinephrine (NE) in patients with septic shock is usually left to the physician’s discretion. No hemodynamic indicator predictive of the possibility of decreasing the NE d...

    Authors: Pierre-Grégoire Guinot, Eugénie Bernard, Mélanie Levrard, Hervé Dupont and Emmanuel Lorne
    Citation: Critical Care 2015 19:14
  12. Impaired microcirculatory perfusion and tissue oxygenation during critical illness are associated with adverse outcome. The aim of this study was to detect alterations in tissue oxygenation or microvascular re...

    Authors: Abele Donati, Elisa Damiani, Roberta Domizi, Claudia Scorcella, Andrea Carsetti, Stefania Tondi, Valentina Monaldi, Erica Adrario, Rocco Romano, Paolo Pelaia and Mervyn Singer
    Citation: Critical Care 2016 20:311
  13. This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at

    Authors: David Antcliffe and Anthony C. Gordon
    Citation: Critical Care 2016 20:68
  14. Innovative treatment modalities have not yet shown a clinical benefit in patients with septic shock. To reduce severe cytokinaemia, CytoSorb as an add-on to continuous renal replacement therapy (CRRT) showed p...

    Authors: Willem Pieter Brouwer, Servet Duran, Martijn Kuijper and Can Ince
    Citation: Critical Care 2019 23:317

    The Letter to this article has been published in Critical Care 2020 24:13

  15. A dysbalanced coagulation system is part of the pathological host response to infection in sepsis. Activation of pro-coagulant pathways and attenuation...

    Authors: Klaus Stahl, Julius J. Schmidt, Benjamin Seeliger, Bernhard M. W. Schmidt, Tobias Welte, Hermann Haller, Marius M. Hoeper, Ulrich Budde, Christian Bode and Sascha David
    Citation: Critical Care 2020 24:71
  16. In recent years, the SOFA score has become extensively used in a range of other applications. A change in the SOFA score of 2 or more is now a defining characteristic of the sepsis syndrome, and the European Medi...

    Authors: Simon Lambden, Pierre Francois Laterre, Mitchell M. Levy and Bruno Francois
    Citation: Critical Care 2019 23:374
  17. The concept of pyrexia as a protective physiological response to aid in host defence has been challenged with the awareness of the severe metabolic stress induced by pyrexia. The host response to pyrexia varies, ...

    Authors: James F. Doyle and Frédérique Schortgen
    Citation: Critical Care 2016 20:303
  18. Progress toward determining the true worth of ongoing practices or value of recent innovations can be glacially slow when we insist on following the conventional stepwise scientific pathway. Moreover, a widely...

    Authors: John J. Marini, Daniel DeBacker, Luciano Gattinoni, Can Ince, Ignacio Martin-Loeches, Pierre Singer, Mervyn Singer, Martin Westphal and Jean-Louis Vincent
    Citation: Critical Care 2019 23(Suppl 1):197

    This article is part of a Supplement: Volume 23 Supplement 1

  19. We performed a metabolomics study on biorepository samples collected from a single academic medical center on 65 adults with systemic inflammatory response syndrome or sepsis treated in a 20-bed medical ICU...

    Authors: Jessica Lasky-Su, Amber Dahlin, Augusto A. Litonjua, Angela J. Rogers, Michael J. McGeachie, Rebecca M. Baron, Lee Gazourian, Diana Barragan-Bradford, Laura E. Fredenburgh, Augustine M. K. Choi, Kris M. Mogensen, Sadeq A. Quraishi, Karin Amrein and Kenneth B. Christopher
    Citation: Critical Care 2017 21:193
  20. Thrombomodulin plays a vital role in maintaining intravascular patency due to its anticoagulant, antiinflammatory, and cytoprotective properties. However, under pathological conditions such as sepsis and systemic...

    Authors: Takashi Ito, Jecko Thachil, Hidesaku Asakura, Jerrold H. Levy and Toshiaki Iba
    Citation: Critical Care 2019 23:280
  21. Persistent peritonitis is a frequent complication of secondary peritonitis requiring additional reoperations and antibiotic therapy. This situation raises specific concerns due to microbiological changes in pe...

    Authors: Philippe Montravers, Guillaume Dufour, Jean Guglielminotti, Mathieu Desmard, Claudette Muller, Hamda Houissa, Nicolas Allou, Jean-Pierre Marmuse and Pascal Augustin
    Citation: Critical Care 2015 19:70
  22. Five hundred forty-nine patients were enrolled; 480 had blood sampling. Plasma IL-8 levels ranged widely from 4 to 7373 pg/mL. Highest IL-8 levels were observed on the day of intubation with subsequent tapering. ...

    Authors: Heidi Flori, Anil Sapru, Michael W. Quasney, Ginny Gildengorin, Martha A. Q. Curley, Michael A. Matthay and Mary K. Dahmer
    Citation: Critical Care 2019 23:128
  23. Sepsis is defined as a life-threatening organ ... the complex and dynamic transcriptome modulations observed in sepsis patients, but a large fraction of the ... This fraction could provide information to better u...

    Authors: Marine Mommert, Olivier Tabone, Audrey Guichard, Guy Oriol, Elisabeth Cerrato, Mélanie Denizot, Valérie Cheynet, Alexandre Pachot, Alain Lepape, Guillaume Monneret, Fabienne Venet, Karen Brengel-Pesce, Julien Textoris and François Mallet
    Citation: Critical Care 2020 24:96
  24. Septic shock, defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, is a highly lethal condition that causes substantial morbidity and mortality among critically ill p...

    Authors: Klaus Kogelmann, Dominik Jarczak, Morten Scheller and Matthias Drüner
    Citation: Critical Care 2017 21:74
  25. We prospectively enrolled all consecutive patients admitted to 21 intensive care units (ICUs) from nine countries and collected baseline characteristics, comorbidities, severity of illness, presence of sepsis, da...

    Authors: F. Garzotto, M. Ostermann, D. Martín-Langerwerf, M. Sánchez-Sánchez, J. Teng, R. Robert, A. Marinho, M. E. Herrera-Gutierrez, H. J. Mao, D. Benavente, E. Kipnis, A. Lorenzin, D. Marcelli, C. Tetta and C. Ronco
    Citation: Critical Care 2016 20:196
  26. We sought to determine the effects of alternative resuscitation strategies on microcirculatory perfusion and examine any association between microcirculatory perfusion and mortality in sepsis.

    Authors: Michael J. Massey, Peter C. Hou, Michael Filbin, Henry Wang, Long Ngo, David T. Huang, William C. Aird, Victor Novack, Stephen Trzeciak, Donald M. Yealy, John A. Kellum, Derek C. Angus and Nathan I. Shapiro
    Citation: Critical Care 2018 22:308
  27. The role of systemic hemodynamics in the pathogenesis of septic acute kidney injury (AKI) has received little attention. The purpose of this study was to investigate the association between systemic hemodynamics ...

    Authors: Matthieu Legrand, Claire Dupuis, Christelle Simon, Etienne Gayat, Joaquim Mateo, Anne-Claire Lukaszewicz and Didier Payen
    Citation: Critical Care 2013 17:R278
  28. Liver microcirculation disturbances are a cause of hepatic failure in sepsis. Increased leukocyte-endothelial interaction, platelet adherence...

    Authors: Roland S Croner, Elfie Hoerer, Yakup Kulu, Tilo Hackert, Martha-Maria Gebhard, Christian Herfarth and Ernst Klar
    Citation: Critical Care 2006 10:R15
  29. That thrombocytopenia results in increased mortality ortransfusion requirements has not been confirmed by previous studies. Weperformed a case-control study in which 36 patients who developed severethrombocyto...

    Authors: François Stephan, Jacquesde Montblanc, Ali Cheffi and Francis Bonnet
    Citation: Critical Care 1999 3:151
  30. In 2006, paediatric intensive care-related subjects were discussed in a number of papers published in various journals, including Critical Care.... Because they focused on the cardiovascular system and its suppor...

    Authors: Carolina F Amoretti and Robert C Tasker
    Citation: Critical Care 2007 11:222
  31. The median (interquartile range) Gas6 concentration was 51 (5 to 95) pg/ml at admission. A positive correlation (Spearman rank-order coefficient [rs] = 0.37, P...= 0.01) was found between Gas6 level and Sepsis-re...

    Authors: Sébastien Gibot, Frédéric Massin, Aurélie Cravoisy, Rachel Dupays, Damien Barraud, Lionel Nace and Pierre-Edouard Bollaert
    Citation: Critical Care 2007 11:R8
  32. We investigated 162 patients undergoing elective surgery for cancer of the gastrointestinal tract. Patients were classified as having no complications (group A), having infection for unknown reason (group B) or h...

    Authors: Michael Siassi, Jutta Riese, Rudi Steffensen, Michael Meisner, Steffen Thiel, Werner Hohenberger and Joachim Schmidt
    Citation: Critical Care 2005 9:R483

    The Erratum to this article has been published in Critical Care 2005 9:458