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  1. The assessment of volume responsiveness and the decision to administer a fluid bolus is a common dilemma facing physicians caring for critically ill patients. Static markers of cardiac preload are poor predict...

    Authors: Steven W Thiel, Marin H Kollef and Warren Isakow
    Citation: Critical Care 2009 13:R111
  2. The study was aimed at verifying whether the occurrence of hypernatremia during the intensive care unit (ICU) stay increases the risk of death in patients with severe traumatic brain injury (TBI). We performed...

    Authors: Umberto Maggiore, Edoardo Picetti, Elio Antonucci, Elisabetta Parenti, Giuseppe Regolisti, Mario Mergoni, Antonella Vezzani, Aderville Cabassi and Enrico Fiaccadori
    Citation: Critical Care 2009 13:R110
  3. Increasing evidence indicates that epidural anesthesia improves postoperative pulmonary function. The underlying mechanisms, however, remain to be determined. Because pulmonary nitric oxide has been identified...

    Authors: Stefan Lauer, Hendrik Freise, Martin Westphal, Alexander Zarbock, Manfred Fobker, Hugo K Van Aken, Andreas W Sielenkämper and Lars G Fischer
    Citation: Critical Care 2009 13:R109
  4. Dysregulation of coagulation and local fibrinolysis found in patients with acute lung injury often results in the need for the support of mechanical ventilation. High-tidal-volume mechanical ventilation can in...

    Authors: Li-Fu Li, Chung-Chi Huang, Horng-Chyuan Lin, Ying-Huang Tsai, Deborah A Quinn and Shuen-Kuei Liao
    Citation: Critical Care 2009 13:R108
  5. Measurement of extravascular lung water (EVLW) by using the lithium-thermal (Li-thermal) and single-thermal indicator dilution methods was compared with the indocyanine green-thermal (ICG-thermal) method in hu...

    Authors: Benjamin Maddison, Christopher Wolff, George Findlay, Peter Radermacher, Charles Hinds and Rupert M Pearse
    Citation: Critical Care 2009 13:R107
  6. Vesicular breath sounds, wheezes, rhonchi, and crackles possess acoustic 'signatures' amenable to detection, quantification, and moment-by-moment visual display. Despite technical hurdles, new methods for soni...

    Authors: John J Marini
    Citation: Critical Care 2009 13:162
  7. Incretins such as glucagon-like peptide-1 (GLP-1) are gut-derived hormones that stimulate insulin secretion and suppress glucagon secretion, thus playing a key role in glucose homeostasis. While incretin mimet...

    Authors: Michelle A Kovalaske and Gunjan Y Gandhi
    Citation: Critical Care 2009 13:161
  8. The influence of brain temperature on clinical outcome after severe brain trauma is currently poorly understood. When brain temperature is measured directly, different values between the inside and outside of ...

    Authors: Charmaine Childs and Graham Machin
    Citation: Critical Care 2009 13:R106
  9. Adiponectin plays an important role in the regulation of tissue inflammation and insulin sensitivity. Perturbations in adiponectin concentration have been associated with obesity and the metabolic syndrome. Da...

    Authors: Bala Venkatesh, Ingrid Hickman, Janelle Nisbet, Jeremy Cohen and John Prins
    Citation: Critical Care 2009 13:R105
  10. Acute kidney injury (AKI) is associated with high mortality rates. New biomarkers that can identify subjects with early AKI (before the increase in serum creatinine) are needed to facilitate appropriate treatm...

    Authors: Kathleen D Liu, Christopher Altmann, Gerard Smits, Catherine D Krawczeski, Charles L Edelstein, Prasad Devarajan and Sarah Faubel
    Citation: Critical Care 2009 13:R104
  11. Since the launch of drotrecogin alfa activated (DrotAA), institutions and individual countries have published data on its use in clinical practice, based on audit or registry data. These studies were limited i...

    Authors: Greg Martin, Frank M Brunkhorst, Jonathan M Janes, Konrad Reinhart, David P Sundin, Kassandra Garnett and Richard Beale
    Citation: Critical Care 2009 13:R103
  12. Severe burn injury remains a major burden on patients and healthcare systems. Following severe burns, the injured tissues mount a local inflammatory response aiming to restore homeostasis. With excessive burn ...

    Authors: Michael A Flierl, Philip F Stahel, Basel M Touban, Kathryn M Beauchamp, Steven J Morgan, Wade R Smith and Kyros R Ipaktchi
    Citation: Critical Care 2009 13:215
  13. The aim of this observational study was to investigate the prevalence of endotoxemia after surgery and its association with ICU length of stay.

    Authors: Franco Valenza, Lorella Fagnani, Silvia Coppola, Sara Froio, Francesca Sacconi, Cecilia Tedesco, Micol Maffioletti, Marta Pizzocri, Valentina Salice, Maria Luisa Ranzi, Cristina Marenghi and Luciano Gattinoni
    Citation: Critical Care 2009 13:R102
  14. In recent years, the use of the consensus definitions of acute kidney injury (RIFLE and AKIN) in the literature has increased substantially. This indicates a highly encouraging acceptance by the medical commun...

    Authors: Dinna N Cruz, Zaccaria Ricci and Claudio Ronco
    Citation: Critical Care 2009 13:211
  15. The effect of sepsis on epidermal wound healing has not been previously studied. It was hypothesised that epidermal wound healing is disturbed in severe sepsis.

    Authors: Marjo Koskela, Fiia Gäddnäs, Tero I Ala-Kokko, Jouko J Laurila, Juha Saarnio, Aarne Oikarinen and Vesa Koivukangas
    Citation: Critical Care 2009 13:R100
  16. The risk factors associated with poor outcome in generalized peritonitis are still debated. Our aim was to analyze clinical and bacteriological factors associated with the occurrence of shock and mortality in ...

    Authors: Florence C Riché, Xavier Dray, Marie-Josèphe Laisné, Joaquim Matéo, Laurent Raskine, Marie-José Sanson-Le Pors, Didier Payen, Patrice Valleur and Bernard P Cholley
    Citation: Critical Care 2009 13:R99
  17. Authors: MLC Vieira, C Nomura, B Tranchesi Jr, B Serpa, G Naccarato, W Oliveira, M Funari, EB Lira Filho, ACT Rodrigues, A Cordovil, C Monaco, R Passos, A Cury, CH Fischer and SS Morhy
    Citation: Critical Care 2009 13(Suppl 3):P29

    This article is part of a Supplement: Volume 13 Supplement 3

  18. Authors: AC Nogueira, RC Borges, VC Pontes, CHM Romero, LGR Júnior, A Colombo, V Kawabata, R Cury, A Dalto, MM Bernike, PA Lutufo, CR Souza, ACT Melo, PC Garcia and FG Soriano
    Citation: Critical Care 2009 13(Suppl 3):P12

    This article is part of a Supplement: Volume 13 Supplement 3