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6921 result(s) for 'sepsis' within Critical Care

Page 55 of 139

  1. Septic shock is characterized by an uncontrolled inflammatory response and microcirculatory dysfunction. There is currently no specific agent for treating septic shock. Anisodamine is an agent extracted from t...

    Authors: Yuetian Yu, Cheng Zhu, Yucai Hong, Lin Chen, Zhiping Huang, Jiancang Zhou, Xin Tian, Dadong Liu, Bo Ren, Cao Zhang, Caibao Hu, Xinan Wang, Rui Yin, Yuan Gao and Zhongheng Zhang
    Citation: Critical Care 2021 25:349
    Content type: Research Published on:

    The Letter to this article has been published in Critical Care 2021 25:433

  2. Interleukin (IL)-18 is a marker of inflammasome activation, and high baseline plasma IL-18 is associated with increased mortality in patients with sepsis-induced ARDS. The aim of this analysis...

    Authors: Andrew James Boyle, Peter Ferris, Ian Bradbury, John Conlon, Manu Shankar-Hari, Angela J. Rogers, Cecilia M. O’Kane and Daniel F. McAuley
    Citation: Critical Care 2022 26:164
    Content type: Research Published on:

  3. The pathophysiology of endotoxemia-induced acute kidney injury (AKI) is characterized by an intense activation of the host immune system and renal resident cells by lipopolysaccharide (LPS) and derived proinfl...

    Authors: Giuseppe Castellano, Alessandra Stasi, Angelica Intini, Margherita Gigante, Anna Maria Di Palma, Chiara Divella, Giuseppe Stefano Netti, Clelia Prattichizzo, Paola Pontrelli, Antonio Crovace, Francesco Staffieri, Enrico Fiaccadori, Nicola Brienza, Giuseppe Grandaliano, Giovanni Pertosa and Loreto Gesualdo
    Citation: Critical Care 2014 18:520
    Content type: Research Published on:

  5. Covid-19 infection was associated with twice the risk of severe maternal morbidity compared with no infection (RR 2.02, 95% CI 1.76–2.31). Risks were elevated for acute renal failure (RR 3.01, 95% CI 1.79–5.06), ...

    Authors: Nathalie Auger, U. Vivian Ukah, Shu Qin Wei, Jessica Healy-Profitós, Ernest Lo and Natalie Dayan
    Citation: Critical Care 2023 27:344
    Content type: Research Published on:

  6. Current protective lung ventilation strategies commonly involve hypercapnia. This approach has resulted in an increase in the clinical acceptability of elevated carbon dioxide tension, with hypoventilation and...

    Authors: Donall O' Croinin, Martina Ni Chonghaile, Brendan Higgins and John G Laffey
    Citation: Critical Care 2004 9:51
    Content type: Review Published on:

  7. Septic shock comprises a heterogeneous population, and individualized resuscitation strategy is of vital importance. The study aimed to identify subclasses of septic shock with non-supervised learning algorith...

    Authors: Penglin Ma, Jingtao Liu, Feng Shen, Xuelian Liao, Ming Xiu, Heling Zhao, Mingyan Zhao, Jing Xie, Peng Wang, Man Huang, Tong Li, Meili Duan, Kejian Qian, Yue Peng, Feihu Zhou, Xin Xin…
    Citation: Critical Care 2021 25:243
    Content type: Research Published on:

  8. ICU-acquired weakness (ICUAW) complicates the disease course of critically ill patients. Inflammation and acute-phase response occur directly within myocytes and contribute to ICUAW. We observed that tripartit...

    Authors: Franziska Schmidt, Melanie Kny, Xiaoxi Zhu, Tobias Wollersheim, Kathleen Persicke, Claudia Langhans, Doerte Lodka, Christian Kleber, Steffen Weber-Carstens and Jens Fielitz
    Citation: Critical Care 2014 18:545
    Content type: Research Published on:

  9. Twenty-three patients (20 women; 87%) of 59.5 ± 14.4 years of age (range, 30 to 89 years) were seen during the study period. Nine (39%) patients were diagnosed with hypothyroidism for the first time at the tim...

    Authors: Pinaki Dutta, Anil Bhansali, Shriq Rashid Masoodi, Sanjay Bhadada, Navneet Sharma and Rajesh Rajput
    Citation: Critical Care 2008 12:R1
    Content type: Research Published on:

  10. The multiple roles of iron in the body have been known for decades, particularly its involvement in iron overload diseases such as hemochromatosis. More recently, compelling evidence has emerged regarding the ...

    Authors: Coralie Grange, François Lux, Thomas Brichart, Laurent David, Aymeric Couturier, David E. Leaf, Bernard Allaouchiche and Olivier Tillement
    Citation: Critical Care 2023 27:475
    Content type: Review Published on:

  11. Diastolic dysfunction as demonstrated by tissue Doppler imaging (TDI), particularly E/e' (peak early diastolic transmitral/peak early diastolic mitral annular velocity) is common in critical illness. In septic...

    Authors: David J Sturgess, Thomas H Marwick, Chris Joyce, Carly Jenkins, Mark Jones, Paul Masci, David Stewart and Bala Venkatesh
    Citation: Critical Care 2010 14:R44
    Content type: Research Published on:

  12. We included 296 RRT-treated critically ill patients. Of 283 patients with complete data on fluid balance, 76 (26.9%) patients had fluid overload. The median (interquartile range) time from ICU admission to RRT...

    Authors: Suvi T Vaara, Anna-Maija Korhonen, Kirsi-Maija Kaukonen, Sara Nisula, Outi Inkinen, Sanna Hoppu, Jouko J Laurila, Leena Mildh, Matti Reinikainen, Vesa Lund, Ilkka Parviainen and Ville Pettilä
    Citation: Critical Care 2012 16:R197
    Content type: Research Published on:

  13. Cytokine adsorption using the CytoSorb® adsorber has been proposed in various clinical settings including sepsis, ARDS, hyperinflammatory syndromes, cardiac surgery or...

    Authors: Sören Becker, Hannah Lang, Clara Vollmer Barbosa, Zhejia Tian, Anette Melk and Bernhard M. W. Schmidt
    Citation: Critical Care 2023 27:215
    Content type: Research Published on:

    The Matters Arising to this article has been published in Critical Care 2023 27:444

    The Matters Arising to this article has been published in Critical Care 2023 27:357

  14. Albumin infusion is the primary therapeutic strategy for septic patients with liver cirrhosis. Although recent studies have investigated the efficacy of albumin in the resuscitation stage of septic patients wi...

    Authors: Wenhan Hu, Hui Chen, Chencheng Ma, Qin Sun, Meicheng Yang, Haofei Wang, Qingyun Peng, Jinlong Wang, Chen Zhang, Wei Huang, Jianfeng Xie and Yingzi Huang
    Citation: Critical Care 2023 27:300
    Content type: Research Published on:

  15. GL improved systemic hemodynamics and protected vital organs against porcine endotoxemia through modulation of the systemic inflammatory response. By reducing the serum level and gene expression of HMGB1 and othe...

    Authors: Wei Wang, Feng Zhao, Yong Fang, Xiantao Li, Lei Shen, Tongwa Cao and Hechen Zhu
    Citation: Critical Care 2013 17:R44
    Content type: Research Published on:

  16. Whether continuous venovenous hemofiltration (CVVHF) is superior to extended daily hemofiltration (EDHF) for the treatment of septic AKI is unknown. We compared the effect of CVVHF (greater than 72 hours) with ED...

    Authors: Zhiping Sun, Hong Ye, Xia Shen, Hongdi Chao, Xiaochun Wu and Junwei Yang
    Citation: Critical Care 2014 18:R70
    Content type: Research Published on:

  17. Poor platelet transfusion response occurred in 349 of the 472 (73.9%) prophylactic platelet transfusions and in 141/181 (77.9%) patients. The mixed-effect model identified haemoglobin at ICU admission (odds ratio...

    Authors: Florian Reizine, Sarah Le Marec, Anthony Le Meur, Maëlys Consigny, Florian Berteau, Laetitia Bodenes, Marie Geslain, Zoe McQuilten, Catherine Le Niger, Julien Huntzinger, Philippe Seguin, Jean-Baptiste Thibert, David Simon, Jean Reignier, Pierre-Yves Egreteau, Jean-Marc Tadié…
    Citation: Critical Care 2023 27:373
    Content type: Research Published on:

  18. A total 815 patients were identified with at least one clinical insult; the most common were sepsis, pneumonia, and pancreatitis. Pulmonary risk conditions ... injury occurred most commonly in the setting of sepsis

    Authors: Niall D Ferguson, Fernando Frutos-Vivar, Andrés Esteban, Federico Gordo, Teresa Honrubia, Oscar Peñuelas, Alejandro Algora, Gema García, Alejandra Bustos and Inmaculada Rodríguez
    Citation: Critical Care 2007 11:R96
    Content type: Research Published on:

  19. Critical illness myopathy and/or neuropathy (CRIMYNE) is frequent in intensive care unit (ICU) patients. Although complete electrophysiological tests of peripheral nerves and muscles are essential to diagnose ...

    Authors: Nicola Latronico, Guido Bertolini, Bruno Guarneri, Marco Botteri, Elena Peli, Serena Andreoletti, Paola Bera, Davide Luciani, Anna Nardella, Elena Vittorielli, Bruno Simini and Andrea Candiani
    Citation: Critical Care 2007 11:R11
    Content type: Research Published on:

  20. Shock is defined as global tissue hypoxia secondary to an imbalance between systemic oxygen delivery and oxygen demand. Venous oxygen saturations represent this relationship between oxygen delivery and oxygen ...

    Authors: Paul van Beest, Götz Wietasch, Thomas Scheeren, Peter Spronk and Michaël Kuiper
    Citation: Critical Care 2011 15:232
    Content type: Review Published on:

  21. The use of low-dose steroid therapy in the management of septic shock has been extensively studied. However, the association between the timing of low-dose steroid therapy and the outcome has not been evaluate...

    Authors: Hye Yun Park, Gee Young Suh, Jae-Uk Song, Hongseok Yoo, Ik Joon Jo, Tae Gun Shin, So Yeon Lim, Sookyoung Woo and Kyeongman Jeon
    Citation: Critical Care 2012 16:R3
    Content type: Research Published on:

  23. The impact of model of end stage liver disease (MELD) score on postoperative morbidity and mortality is still elusive, especially for high MELD. There are reports of poorer patient outcome in transplant candid...

    Authors: Christian E Oberkofler, Philipp Dutkowski, Reto Stocker, Reto A Schuepbach, John F Stover, Pierre-Alain Clavien and Markus Béchir
    Citation: Critical Care 2010 14:R117
    Content type: Research Published on:

  25. The PI was significantly correlated with baseline PtcO2, 10min-OCT and oxygen challenge index (OCI) in all the patients. The control group had a higher baseline PtcO2..., 10min-OCT and PI than the septic shock gr...

    Authors: Huai-wu He, Da-wei Liu, Yun Long and Xiao-ting Wang
    Citation: Critical Care 2013 17:R116
    Content type: Research Published on:

  26. Ventilator-associated pneumonia (VAP) is the most commonly acquired infection in intensive care units (ICU). Its outcome is related, at least in part, to the host’s response. Statins have anti-inflammatory eff...

    Authors: Rémi Bruyere, Clara Vigneron, Sébastien Prin, André Pechinot, Jean-Pierre Quenot, Serge Aho, Laurent Papazian and Pierre-Emmanuel Charles
    Citation: Critical Care 2014 18:R83
    Content type: Research Published on:

  29. We review key research papers in cardiology and intensive care published during 2010 in Critical Care and quote related studies published in other journals if appropriate. Papers were grouped into the following c...

    Authors: Daniel De Backer and Sabino Scolletta
    Citation: Critical Care 2011 15:241
    Content type: Review Published on:

  30. Community acquired pneumonia (CAP) is the most common infectious reason for admission to the Intensive Care Unit (ICU). The GenOSept study was designed to determine genetic influences on sepsis outcome. Phenotypi...

    Authors: Andrew P Walden, Geraldine M Clarke, Stuart McKechnie, Paula Hutton, Anthony C Gordon, Jordi Rello, Jean-Daniel Chiche, Frank Stueber, Christopher S Garrard and Charles J Hinds
    Citation: Critical Care 2014 18:R58
    Content type: Research Published on:

  31. A total of 1740 ECMO catheter days in 192 patients were studied. These were divided into 855 ECMO catheter days in 96 patients before and 885 ECMO catheter days in 96 patients during the intervention. The rate...

    Authors: Hye Ju Yeo, Dohyung Kim, Mihyang Ha, Hyung Gon Je, Jeong Soo Kim and Woo Hyun Cho
    Citation: Critical Care 2020 24:595
    Content type: Research Published on:

  32. Neutrophil granulocytes are the first defense line in bacterial infections. However, granulocytes are also responsible for severe local tissue impairment. In order to use donor granulocytes, but at the same ti...

    Authors: Jens Altrichter, Martin Sauer, Katharina Kaftan, Thomas Birken, Doris Gloger, Martin Gloger, Jörg Henschel, Heiko Hickstein, Ernst Klar, Sebastian Koball, Annette Pertschy, Gabriele Nöldge-Schomburg, Dierk A Vagts and Steffen R Mitzner
    Citation: Critical Care 2011 15:R82
    Content type: Research Published on:

  33. Overall, 60% of the patients had delayed GE and a mean GEC of 2.9 ± 0.1 and t50 of 163 ± 7 minutes. On univariate analysis, GE correlated significantly with older age, higher admission APACHE II scores, longer...

    Authors: Nam Q Nguyen, Mei P Ng, Marianne Chapman, Robert J Fraser and Richard H Holloway
    Citation: Critical Care 2007 11:R16
    Content type: Research Published on:

  34. The research papers on shock that have been published in Critical Care...throughout 2009 are related to four major subjects: first, alterations of heart function and, second, the role of the sympathetic central n...

    Authors: Wolfgang Stahl, Hendrik Bracht, Peter Radermacher and Jörg Thomas
    Citation: Critical Care 2010 14:239
    Content type: Review Published on:

  35. Recent work has shown that benzodiazepines interact with the immune system and exhibit anti-inflammatory effects. By using in vitro models, researchers in several studies have shown that the peptidergic endogenou...

    Authors: Thomas Clavier, Marie-Christine Tonon, Anne Foutel, Emmanuel Besnier, Antoine Lefevre-Scelles, Fabrice Morin, Pierrick Gandolfo, Jean-Jacques Tuech, Muriel Quillard, Benoit Veber, Bertrand Dureuil, Hélène Castel and Vincent Compère
    Citation: Critical Care 2014 18:633
    Content type: Research Published on:

  36. Several studies link hematological dysfunction to severity of sepsis. Previously we showed that platelet-derived microparticles...

    Authors: Marcela Helena Gambim, Alipio de Oliveira do Carmo, Luciana Marti, Sidney Veríssimo-Filho, Lucia Rossetti Lopes and Mariano Janiszewski
    Citation: Critical Care 2007 11:R107
    Content type: Research Published on:

  37. Plasma from patients with septic shock induces loss of myosin and activates key regulators of proteolysis in skeletal myotubes. IL-6 is an important player in sepsis-induced muscle atrophy in this model. The ... ...

    Authors: Hieronymus WH van Hees, Willem-Jan M Schellekens, Marianne Linkels, Floris Leenders, Jan Zoll, Rogier Donders, PN Richard Dekhuijzen, Johannes G van der Hoeven and Leo MA Heunks
    Citation: Critical Care 2011 15:R233
    Content type: Research Published on:

  38. Low blood pressure, inadequate tissue oxygen delivery and mitochondrial dysfunction have all been implicated in the development of sepsis-induced organ failure. This study evaluated the ... using norepinephrine t...

    Authors: Tomas Regueira, Bertram Bänziger, Siamak Djafarzadeh, Sebastian Brandt, Jose Gorrasi, Jukka Takala, Philipp M Lepper and Stephan M Jakob
    Citation: Critical Care 2008 12:R88
    Content type: Research Published on:

  40. Severe burn is a systemic illness often complicated by sepsis. Kidney is one of the organs invariably ... systemic inflammatory state in burns patients who developed sepsis-associated acute renal failure (ARF). W...

    Authors: Filippo Mariano, Vincenzo Cantaluppi, Maurizio Stella, Giuseppe Mauriello Romanazzi, Barbara Assenzio, Monica Cairo, Luigi Biancone, Giorgio Triolo, VMarco Ranieri and Giovanni Camussi
    Citation: Critical Care 2008 12:R42
    Content type: Research Published on:

  41. Organ dysfunction or overt failure is a commonplace event in the critically ill affecting up to 70% of patients during their stay in the ICU. The outcome depends on the resolution of impaired organ function, w...

    Authors: Aritz Perez Ruiz de Garibay, Andreas Kortgen, Julia Leonhardt, Alexander Zipprich and Michael Bauer
    Citation: Critical Care 2022 26:289
    Content type: Review Published on:

  42. Our protocol was registered in PROSPERO (CRD42020165146). We searched PubMed, the Cochrane Database, and Embase from inception until February 15, 2022. We selected studies that reported Hb before and after rapid ...

    Authors: Armin A. Quispe-Cornejo, Ana L. Alves da Cunha, Hassane Njimi, Wasineenart Mongkolpun, Ana L. Valle-Martins, Mónica Arébalo-López, Jacques Creteur and Jean-Louis Vincent
    Citation: Critical Care 2022 26:324
    Content type: Research Published on:

  44. ...30 consecutive patients were enrolled to this prospective interventional open label study and assigned either to a traditional 'crystalloids only' or to a 'HES 200/0.5 (10%)' volume resuscitation protocol. Tot...

    Authors: Markus Béchir, Milo A Puhan, Simona B Neff, Merlin Guggenheim, Volker Wedler, John F Stover, Reto Stocker and Thomas A Neff
    Citation: Critical Care 2010 14:R123
    Content type: Research Published on:

  45. A randomized, double-blind, multicenter clinical trial of enteral administration of L-citrulline versus placebo for critically ill adult patients under invasive mechanical ventilation without sepsis or septic sho...

    Authors: Jean-Marc Tadié, Clara Locher, Adel Maamar, Jean Reignier, Pierre Asfar, Morgane Commereuc, Mathieu Lesouhaitier, Murielle Gregoire, Estelle Le Pabic, Claude Bendavid, Caroline Moreau, Jean-Luc Diehl, Alain Gey, Eric Tartour, Yves Le Tulzo, Ronan Thibault…
    Citation: Critical Care 2023 27:381
    Content type: Research Published on:

  46. The organs of the hepatosplanchnic system are considered to play a key role in the development of multiorgan failure during septic shock. Impaired oxygenation of the intestinal mucosa can lead to disruption of...

    Authors: Pierre Asfar, Daniel De Backer, Andreas Meier-Hellmann, Peter Radermacher and Samir G Sakka
    Citation: Critical Care 2003 8:170
    Content type: Review Published on:

  47. At the time of cTNT rise, 100 patients (70%) were septic and 58% were on vasopressors. Patients who were septic when cTNT was elevated had an ICU mortality of 28% compared to 9% in patients without sepsis. ICU mo...

    Authors: Marlies Ostermann, Jessica Lo, Michael Toolan, Emma Tuddenham, Barnaby Sanderson, Katie Lei, John Smith, Anna Griffiths, Ian Webb, James Coutts, John Chambers, Paul Collinson, Janet Peacock, David Bennett and David Treacher
    Citation: Critical Care 2014 18:R62
    Content type: Research Published on:

  48. Mechanisms underlying inotropic failure in septic shock are incompletely understood. We previously identified the presence of exosomes in the plasma of septic shock patients. These exosomes are released mainly by...

    Authors: Luciano Cesar Pontes Azevedo, Mariano Janiszewski, Vera Pontieri, Marcelo de Almeida Pedro, Estevão Bassi, Paulo José Ferreira Tucci and Francisco Rafael Martins Laurindo
    Citation: Critical Care 2007 11:R120
    Content type: Research Published on:

  49. In 12 months, 177 patients received haloperidol prophylaxis. Except for sepsis, patient characteristics were comparable between the prevention...n = 299) groups. Predicted chance to develop delirium was 75 ± 19% ...

    Authors: Mark van den Boogaard, Lisette Schoonhoven, Theo van Achterberg, Johannes G van der Hoeven and Peter Pickkers
    Citation: Critical Care 2013 17:R9
    Content type: Research Published on:

  50. The combination therapy of hydrocortisone, vitamin C, and thiamine has been proposed as a potential treatment in patients with sepsis and septic shock. However, subsequent trials...

    Authors: Qing-Quan Lyu, Rui-Qiang Zheng, Qi-Hong Chen, Jiang-Quan Yu, Jun Shao and Xiao-Hua Gu
    Citation: Critical Care 2022 26:295
    Content type: Research Published on:
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Critical Care

ISSN: 1364-8535