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6921 result(s) for 'sepsis' within Critical Care

Page 47 of 139

  1. Donnino and colleagues provide new insights into the field of oxidative stress and mitochondrial dysfunction during septic shock. These authors suggest a coenzyme Q10 (CoQ10) deficiency in patients with septic sh...

    Authors: Laurent Dupic, Olivier Huet and Jacques Duranteau
    Citation: Critical Care 2011 15:194
  2. The sepsis resuscitation bundle is the result of an effort on behalf of the Surviving Sepsis Campaign and the Institute for Healthcare Improvement ... seminal early goal-directed therapy trial for severe sepsis a...

    Authors: Anthony M Napoli and Todd A Seigel
    Citation: Critical Care 2011 15:199
  3. Epidemiology studies are an essential part of clinical research, often forming the foundation for studies ranked more highly in the hierarchy of evidence-based medicine. Studies of sepsis to date have been conduc...

    Authors: Greg Martin
    Citation: Critical Care 2006 10:136
  4. Albumin solutions have been used worldwide for the treatment of critically ill patients since they became commercially available in the 1940s. However, their use has become the subject of criticism and debate ...

    Authors: Jean-Louis Vincent, James A Russell, Matthias Jacob, Greg Martin, Bertrand Guidet, Jan Wernerman, Ricard Ferrer Roca, Stuart A McCluskey and Luciano Gattinoni
    Citation: Critical Care 2014 18:231

    The Erratum to this article has been published in Critical Care 2014 18:630

  5. A prospective database with mixed medical-surgical critically ill patients with prolonged mechanical ventilation (>72 hours) and measured energy expenditure was used in this study. Logistic regression analysis wa...

    Authors: Peter JM Weijs, Wilhelmus GPM Looijaard, Albertus Beishuizen, Armand RJ Girbes and Heleen M Oudemans-van Straaten
    Citation: Critical Care 2014 18:701
  6. A low ACTH response occurred in 63% of patients. Predictors, in multivariate analysis, included sepsis at admission, low platelets, low pH...r = -0.21; P < 0.0001).

    Authors: Margriet FC de Jong, Albertus Beishuizen, Jan-Jaap Spijkstra, Armand RJ Girbes, Rob JM Strack van Schijndel, Jos WR Twisk and AB Johan Groeneveld
    Citation: Critical Care 2007 11:R61
  7. Clinically useful predictions of end-organ function and failure in severe sepsis may be possible through analyzing the interactions ... database of medical and surgical patients with severe sepsis and/or septic s...

    Authors: Gus J Slotman
    Citation: Critical Care 2000 4:319
  8. This study sought to assess the prognostic value of the kinetics of procalcitonin (PCT), C-reactive protein (CRP) and clinical scores (clinical pulmonary infection score (CPIS), Sequential Organ Failure Assess...

    Authors: Renato Seligman, Michael Meisner, Thiago C Lisboa, Felipe T Hertz, Tania B Filippin, Jandyra MG Fachel and Paulo JZ Teixeira
    Citation: Critical Care 2006 10:R125
  9. The dysfunction and decrease of endothelial progenitor cells (EPCs) may play a very important role in the initiation of organ dysfunction caused by trauma or severe sepsis. We aim to measure the number and ... or...

    Authors: Tian Hang Luo, Yao Wang, Zheng Mao Lu, Hong Zhou, Xu Chao Xue, Jian Wei Bi, Li Ye Ma and Guo En Fang
    Citation: Critical Care 2009 13:R118
  10. The overall outcome of septic shock has been recently improved. We sought to determine whether this survival gain extends to the high-risk subgroup of patients with cirrhosis.

    Authors: Bertrand Sauneuf, Benoit Champigneulle, Alexis Soummer, Nicolas Mongardon, Julien Charpentier, Alain Cariou, Jean-Daniel Chiche, Vincent Mallet, Jean-Paul Mira and Frédéric Pène
    Citation: Critical Care 2013 17:R78
  11. Sepsis guidelines suggest immediate start of resuscitation for...

    Authors: Maria Evangelia Adami, Antigone Kotsaki, Nikolaos Antonakos, Efthymia Giannitsioti, Stamatios Chalvatzis, Maria Saridaki, Christina Avgoustou, Karolina Akinosoglou, Konstantina Dakou, Georgia Damoraki, Konstantina Katrini, Panagiotis Koufargyris, Vasileios Lekakis, Antonia Panagaki, Asimina Safarika, Jesper Eugen-Olsen…
    Citation: Critical Care 2024 28:42

    The Matters Arising to this article has been published in Critical Care 2024 28:190

    The Matters Arising to this article has been published in Critical Care 2024 28:161

  12. The 40-year-old experience with glucocorticosteroids (GCs) in the context of severe infections is complex and troublesome. Recently, however, a clear indication for GCs in severe COVID-19 has been established....

    Authors: Martin S. Winkler, Marcin F. Osuchowski, Didier Payen, Antoni Torres, Steffen Dickel and Tomasz Skirecki
    Citation: Critical Care 2022 26:308
  13. Septic syndromes represent a major healthcare problem worldwide. Clinical and experimental evidence indicates that septic patients rapidly present with numerous compromised immune functions. Although flow cytomet...

    Authors: Fabienne Venet, Alain Lepape and Guillaume Monneret
    Citation: Critical Care 2011 15:231
  14. The interdependence between endotoxemia, gram negative (GN) bacteremia and mortality has been extensively studied. Underlying patient risk and GN bacteremia types are possible confounders of the relationship.

    Authors: James C Hurley, Bertrand Guidet, Georges Offenstadt and Eric Maury
    Citation: Critical Care 2012 16:R148
  15. Sepsis-induced myopathy and critical illness myopathy (CIM ... membrane properties in the early stage of experimental sepsis by evaluating muscle excitability.

    Authors: Karin A Ackermann, Hugh Bostock, Lukas Brander, Ralph Schröder, Siamak Djafarzadeh, Daniel Tuchscherer, Stephan M Jakob, Jukka Takala and Werner J Z’Graggen
    Citation: Critical Care 2014 18:484
  16. Despite recent advances in the management of septic shock, mortality rates are still unacceptably high. Early identification of the high-mortality risk group for early intervention remains an issue under explorat...

    Authors: Kuang-Yao Yang, Kuan-Ting Liu, Yu-Chun Chen, Chun-Sheng Chen, Yu-Chin Lee, Reury-Perng Perng and Jia-Yih Feng
    Citation: Critical Care 2011 15:R11
  17. Blood culture (BC) testing before initiation of antimicrobial therapy is recommended as a standard of care in international sepsis guidelines and has been shown to reduce...

    Authors: Roland PH Schmitz, Peter M Keller, Michael Baier, Stefan Hagel, Mathias W Pletz and Frank M Brunkhorst
    Citation: Critical Care 2013 17:R248
  18. Endothelial cell injury is an important component of acute lung injury. Platelet-endothelial cell adhesion molecule-1 (PECAM1) is a transmembrane protein that connects endothelial cells to one another and can ...

    Authors: Jesús Villar, Mercedes Muros, Nuria E Cabrera-Benítez, Francisco Valladares, Milagros López-Hernández, Carlos Flores, José L Martín-Barrasa, Jesús Blanco, Mingyao Liu and Robert M Kacmarek
    Citation: Critical Care 2014 18:R41
  19. The transcriptomic score provides a useful and reliable companion diagnostic tool to further develop immune modulating drugs in sepsis in the context of personalized medicine.

    Authors: Maxime Bodinier, Guillaume Monneret, Marie Casimir, Aurore Fleurie, Filippo Conti, Fabienne Venet, Marie-Angélique Cazalis, Elisabeth Cerrato, Estelle Peronnet, Thomas Rimmelé, Anne-Claire Lukaszewicz, Karen Brengel-Pesce and Jean-François Llitjos
    Citation: Critical Care 2023 27:158
  20. In septic shock patients, the prevalence of low (<70%) central venous oxygen saturation (ScvO2) on admission to the intensive care unit (ICU) and its relationship to outcome are unknown. The objectives of the pre...

    Authors: Thierry Boulain, Denis Garot, Philippe Vignon, Jean-Baptiste Lascarrou, Arnaud Desachy, Vlad Botoc, Arnaud Follin, Jean-Pierre Frat, Frédéric Bellec, Jean-Pierre Quenot, Armelle Mathonnet and Pierre-François Dequin
    Citation: Critical Care 2014 18:609
  21. A systematic review and meta-analysis of publications between 1966 and 2013 was performed. The review was limited to randomized-controlled trials that compared HVHF (effluent rate greater than 50 ml/kg per hour) ...

    Authors: Edward Clark, Amber O Molnar, Olivier Joannes-Boyau, Patrick M Honoré, Lindsey Sikora and Sean M Bagshaw
    Citation: Critical Care 2014 18:R7
  22. The endothelial specific angiopoietin (Ang)-Tie2 ligand-receptor system has been identified as a non-redundant mediator of endothelial activation in experimental sepsis. Binding of circulating Ang-1 to the...

    Authors: Philipp Kümpers, Alexander Lukasz, Sascha David, Rüdiger Horn, Carsten Hafer, Robert Faulhaber-Walter, Danilo Fliser, Hermann Haller and Jan T Kielstein
    Citation: Critical Care 2008 12:R147
  23. This prospective, multicentre, observational study was carried out in 47 French EDs for 6 months. Patients were adults presenting at the ED with FN after myelotoxic treatment for cancer. Severity of infection was...

    Authors: Stéphanie André, Pierre Taboulet, Caroline Elie, Noël Milpied, Michel Nahon, Gérald Kierzek, Mariève Billemont, Franck Perruche, Sandrine Charpentier, Hélène Clément, Jean-Louis Pourriat and Yann-Erick Claessens
    Citation: Critical Care 2010 14:R68
  24. Heterogeneity of acute respiratory distress syndrome (ARDS) could be reduced by identification of biomarker-based phenotypes. The set of ARDS biomarkers to prospectively define these phenotypes remains to be e...

    Authors: Philip van der Zee, Wim Rietdijk, Peter Somhorst, Henrik Endeman and Diederik Gommers
    Citation: Critical Care 2020 24:243
  25. Severe sepsis is a disease of the microcirculation, with...

    Authors: Limangeni A Mankhambo, Daniel L Banda, Graham Jeffers, Sarah A White, Paul Balmer, Standwell Nkhoma, Happy Phiri, Elizabeth M Molyneux, C Anthony Hart, Malcolm E Molyneux, Robert S Heyderman and Enitan D Carrol
    Citation: Critical Care 2010 14:R91
  26. Multiple organ dysfunction syndrome (MODS) is a critical driver of sepsis morbidity and mortality in children. Early identification ... necessary to enrich patients for future trials of sepsis therapeutics. Here,...

    Authors: Mihir R. Atreya, Natalie Z. Cvijanovich, Julie C. Fitzgerald, Scott L. Weiss, Michael T. Bigham, Parag N. Jain, Adam J. Schwarz, Riad Lutfi, Jeffrey Nowak, Geoffrey L. Allen, Neal J. Thomas, Jocelyn R. Grunwell, Torrey Baines, Michael Quasney, Bereketeab Haileselassie, Christopher J. Lindsell…
    Citation: Critical Care 2022 26:210
  27. There is a hyperoxidative state in sepsis. The objective of this study was to...

    Authors: Leonardo Lorente, María M Martín, Pedro Abreu-González, Alberto Domínguez-Rodriguez, Lorenzo Labarta, César Díaz, Jordi Solé-Violán, José Ferreres, Judith Cabrera, Jose Carlos Igeño and Alejandro Jiménez
    Citation: Critical Care 2013 17:R290
  28. Increasing evidence supports a role for mitochondrial dysfunction in organ injury and immune dysregulation in sepsis. Although differential expression of mitochondrial genes in ... about the blood cell mitochondr...

    Authors: Scott L Weiss, Natalie Z Cvijanovich, Geoffrey L Allen, Neal J Thomas, Robert J Freishtat, Nick Anas, Keith Meyer, Paul A Checchia, Thomas P Shanley, Michael T Bigham, Julie Fitzgerald, Sharon Banschbach, Eileen Beckman, Kelli Howard, Erin Frank, Kelli Harmon…
    Citation: Critical Care 2014 18:623
  29. A pro-apoptotic effect of circulating mediators on renal tubular epithelial cells has been involved in the pathogenesis of sepsis-associated acute kidney injury (AKI). Adsorption...

    Authors: Vincenzo Cantaluppi, Viktoria Weber, Carola Lauritano, Federico Figliolini, Silvia Beltramo, Luigi Biancone, Massimo De Cal, Dinna Cruz, Claudio Ronco, Giuseppe Paolo Segoloni, Ciro Tetta and Giovanni Camussi
    Citation: Critical Care 2010 14:R4
  30. Intravenous vitamin C administration in septic shock may have a sparing effect on vasopressor requirements, and vitamin C’s enzyme cofactor functions provide a mechanistic rationale. Our study aimed to determi...

    Authors: Patrice Rosengrave, Emma Spencer, Jonathan Williman, Jan Mehrtens, Stacey Morgan, Tara Doyle, Kymbalee Van Der Heyden, Anna Morris, Geoff Shaw and Anitra C. Carr
    Citation: Critical Care 2022 26:26