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  1. Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has presently become a rapidly spreading and devastating global pandemic. Veno-venous extracorporeal membrane oxygenation (V-V ECMO) ...

    Authors: Mariusz Kowalewski, Dario Fina, Artur Słomka, Giuseppe Maria Raffa, Gennaro Martucci, Valeria Lo Coco, Maria Elena De Piero, Marco Ranucci, Piotr Suwalski and Roberto Lorusso
    Citation: Critical Care 2020 24:205
  2. The role of site of infection in sepsis has been poorly characterized. Additionally, sepsis epidemiology has evolved. Early mortality has decreased, but many survivors now progress into chronic critical illnes...

    Authors: Julie A. Stortz, Michael C. Cox, Russell B. Hawkins, Gabriela L. Ghita, Babette A. Brumback, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron, Scott C. Brakenridge and Frederick A. Moore
    Citation: Critical Care 2020 24:203
  3. The use of the furosemide stress test (FST) as an acute kidney injury (AKI) severity marker has been described in several trials. However, the diagnostic performance of the FST in predicting AKI progression ha...

    Authors: Jia-Jin Chen, Chih-Hsiang Chang, Yen-Ta Huang and George Kuo
    Citation: Critical Care 2020 24:202
  4. The use of an ultrasound-guided technique for radial arterial catheterization has not been well established in pediatric patients. We conducted a systematic review and meta-analysis to evaluate the efficacy of...

    Authors: Wen Zhang, Kunpeng Li, Hui Xu, Dawei Luo, Changbin Ji, Keshi Yang and Qinghua Zhao
    Citation: Critical Care 2020 24:197
  5. In order to assess the significance of drug/substance levels measured in intensive care medicine and clinical and forensic toxicology as well as for therapeutic drug monitoring, it is essential that a comprehe...

    Authors: Martin Schulz, Achim Schmoldt, Hilke Andresen-Streichert and Stefanie Iwersen-Bergmann
    Citation: Critical Care 2020 24:195
  6. The aim of this review is to describe variation in standards and guidelines on ‘heating, ventilation and air-conditioning (HVAC)’ system maintenance in the intensive care units, across the world, which is requ...

    Authors: Sai Saran, Mohan Gurjar, Arvind Baronia, Vijayalakshmi Sivapurapu, Pralay S. Ghosh, Gautham M. Raju and Indubala Maurya
    Citation: Critical Care 2020 24:194
  7. In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinic...

    Authors: Dawei Wang, Yimei Yin, Chang Hu, Xing Liu, Xingguo Zhang, Shuliang Zhou, Mingzhi Jian, Haibo Xu, John Prowle, Bo Hu, Yirong Li and Zhiyong Peng
    Citation: Critical Care 2020 24:188
  8. In the publication of this article [1], there was an error in Fig. 1 which caused that the a, b were switched and ‘b’ was missing as a caption on Fig. 1b.

    Authors: Karin Thevissen, Cato Jacobs, Michelle Holtappels, Mitsuru Toda, Paul Verweij and Joost Wauters
    Citation: Critical Care 2020 24:186

    The original article was published in Critical Care 2020 24:84

  9. Arginine vasopressin has complex actions in critically ill patients, involving vasoregulatory status, plasma volume, and cortisol levels. Copeptin, a surrogate marker for arginine vasopressin, has shown promis...

    Authors: Joachim Düring, Martin Annborn, Tobias Cronberg, Josef Dankiewicz, Yvan Devaux, Christian Hassager, Janneke Horn, Jesper Kjaergaard, Michael Kuiper, Homa Rafi Nikoukhah, Pascal Stammet, Johan Undén, Michael Jaeger Wanscher, Matt Wise, Hans Friberg and Niklas Nielsen
    Citation: Critical Care 2020 24:185
  10. The novel coronavirus, SARS-CoV-2-causing Coronavirus Disease 19 (COVID-19), emerged as a public health threat in December 2019 and was declared a pandemic by the World Health Organization in March 2020. Delir...

    Authors: Katarzyna Kotfis, Shawniqua Williams Roberson, Jo Ellen Wilson, Wojciech Dabrowski, Brenda T. Pun and E. Wesley Ely
    Citation: Critical Care 2020 24:176

    The Letter to this article has been published in Critical Care 2020 24:375

  11. Arterial blood pressure (BP) is a fundamental cardiovascular variable, is routinely measured in perioperative and intensive care medicine, and has a significant impact on patient management. The clinical refer...

    Authors: Bernd Saugel, Karim Kouz, Agnes S. Meidert, Leonie Schulte-Uentrop and Stefano Romagnoli
    Citation: Critical Care 2020 24:172

    The Correction to this article has been published in Critical Care 2020 24:374

  12. Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or ou...

    Authors: Jean-Louis Vincent, Andrew Ferguson, Peter Pickkers, Stephan M. Jakob, Ulrich Jaschinski, Ghaleb A. Almekhlafi, Marc Leone, Majid Mokhtari, Luis E. Fontes, Philippe R. Bauer and Yasser Sakr
    Citation: Critical Care 2020 24:171
  13. Dipeptidyl peptidase-3 (DPP3) is a metallopeptidase which cleaves bioactive peptides, notably angiotensin II, and is involved in inflammation regulation. DPP3 has been proposed to be a myocardial depressant fa...

    Authors: François Dépret, Juliette Amzallag, Adrien Pollina, Laure Fayolle-Pivot, Maxime Coutrot, Maïté Chaussard, Karine Santos, Oliver Hartmann, Marion Jully, Alexandre Fratani, Haikel Oueslati, Alexandru Cupaciu, Mourad Benyamina, Lucie Guillemet, Benjamin Deniau, Alexandre Mebazaa…
    Citation: Critical Care 2020 24:168
  14. Acute kidney injury (AKI) is a frequent and clinically relevant problem in critically ill patients. Various randomized controlled trials (RCT) have attempted to assess potentially beneficial treatments for AKI...

    Authors: Renske Wiersema, Sakari Jukarainen, Ruben J. Eck, Thomas Kaufmann, Jacqueline Koeze, Frederik Keus, Ville Pettilä, Iwan C. C. van der Horst and Suvi T. Vaara
    Citation: Critical Care 2020 24:164
  15. Early detection of cardiovascular dysfunctions directly caused by acute ischemic stroke (AIS) has become paramount. Researchers now generally agree on the existence of a bidirectional interaction between the b...

    Authors: Denise Battaglini, Chiara Robba, Adriana Lopes da Silva, Cynthia dos Santos Samary, Pedro Leme Silva, Felipe Dal Pizzol, Paolo Pelosi and Patricia Rieken Macedo Rocco
    Citation: Critical Care 2020 24:163
  16. While delirium prevalence and duration are each associated with increased 30-day, 6-month, and 1-year mortality, the association between incident ICU delirium and mortality remains unclear. We evaluated the as...

    Authors: Matthew S. Duprey, Mark van den Boogaard, Johannes G. van der Hoeven, Peter Pickkers, Becky A. Briesacher, Jane S. Saczynski, John L. Griffith and John W. Devlin
    Citation: Critical Care 2020 24:161
  17. Guidelines recommend a restrictive red blood cell transfusion strategy based on hemoglobin (Hb) concentrations in critically ill patients. We hypothesized that the arterial-venous oxygen difference (A-V O2diff), ...

    Authors: Alberto Fogagnolo, Fabio Silvio Taccone, Jean Louis Vincent, Giulia Benetto, Elaine Cavalcante, Elisabetta Marangoni, Riccardo Ragazzi, Jacques Creteur, Carlo Alberto Volta and Savino Spadaro
    Citation: Critical Care 2020 24:160

    The Correction to this article has been published in Critical Care 2022 26:254