Articles
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Citation: Critical Care 2020 24:413
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Angiotensin II treatment in COVID-19 patients: more risk than benefit? A single-center experience
Citation: Critical Care 2020 24:409 -
Transpulmonary pressure in SARS-CoV-2-associated acute respiratory distress syndrome: a single-center observational study
Citation: Critical Care 2020 24:408 -
Unrecognized diabetes in critically ill COVID-19 patients
Citation: Critical Care 2020 24:406 -
Molecular mechanisms of sex bias differences in COVID-19 mortality
More men than women have died from COVID-19. Genes encoded on X chromosomes, and sex hormones may explain the decreased fatality of COVID-19 in women. The angiotensin-converting enzyme 2 gene is located on X c...
Citation: Critical Care 2020 24:405 -
The effect of short-course antibiotics on the resistance profile of colonizing gut bacteria in the ICU: a prospective cohort study
The need for early antibiotics in the intensive care unit (ICU) is often balanced against the goal of antibiotic stewardship. Long-course antibiotics increase the burden of antimicrobial resistance within colo...
Citation: Critical Care 2020 24:404 -
Brain natriuretic peptide to predict successful liberation from mechanical ventilation in critically ill patients: the results need to be interpreted with more caution
Citation: Critical Care 2020 24:403 -
Is delirium a specific complication of viral acute respiratory distress syndrome?
Citation: Critical Care 2020 24:401 -
Visualisation of epidemiological map using an Internet of Things infectious disease surveillance platform
Citation: Critical Care 2020 24:400 -
Classification of COVID-19 in intensive care patients
Citation: Critical Care 2020 24:399 -
Identification, collection, and reporting of harms among non-industry-sponsored randomized clinical trials of pharmacologic interventions in the critically ill population: a systematic review
Prescribing pharmacologic therapies for critically ill patients requires a careful balancing of risks and benefits. Defining, monitoring, and reporting harms that occur in clinical trials conducted in critical...
Citation: Critical Care 2020 24:398 -
Prone positioning in severe ARDS requiring extracorporeal membrane oxygenation
Prone positioning (PP) has shown to improve survival in patients with severe acute respiratory distress syndrome (ARDS). To this point, it is unclear if PP is also beneficial for ARDS patients treated with ven...
Citation: Critical Care 2020 24:397 -
Clarifying the controversial risk-benefit profile of soluble ACE2 in COVID-19
Citation: Critical Care 2020 24:396 -
COVID-19: a hypothesis regarding the ventilation-perfusion mismatch
Citation: Critical Care 2020 24:395 -
Clinical course and predictors of 60-day mortality in 239 critically ill patients with COVID-19: a multicenter retrospective study from Wuhan, China
The global numbers of confirmed cases and deceased critically ill patients with COVID-19 are increasing. However, the clinical course, and the 60-day mortality and its predictors in critically ill patients hav...
Citation: Critical Care 2020 24:394 -
Recommendations for core critical care ultrasound competencies as a part of specialist training in multidisciplinary intensive care: a framework proposed by the European Society of Intensive Care Medicine (ESICM)
Critical care ultrasound (CCUS) is an essential component of intensive care practice. Although existing international guidelines have focused on training principles and determining competency in CCUS, few coun...
Citation: Critical Care 2020 24:393 -
Nafamostat mesylate treatment in combination with favipiravir for patients critically ill with Covid-19: a case series
Citation: Critical Care 2020 24:392 -
Causes and characteristics of death in patients with acute hypoxemic respiratory failure and acute respiratory distress syndrome: a retrospective cohort study
Acute hypoxemic respiratory failure (AHRF) and acute respiratory distress syndrome (ARDS) are associated with high in-hospital mortality. However, in cohorts of ARDS patients from the 1990s, patients more comm...
Citation: Critical Care 2020 24:391 -
Virtual reality device training for extracorporeal membrane oxygenation
Citation: Critical Care 2020 24:390 -
Acute complications and mortality in hospitalized patients with coronavirus disease 2019: a systematic review and meta-analysis
The incidence of acute complications and mortality associated with COVID-19 remains poorly characterized. The aims of this systematic review and meta-analysis were to summarize the evidence on clinically relev...
Citation: Critical Care 2020 24:389 -
Rapid establishment of an ICU using anesthesia ventilators during COVID-19 pandemic: lessons learned
Citation: Critical Care 2020 24:388 -
Significance of body temperature in elderly patients with sepsis
Elderly patients have a blunted host response, which may influence vital signs and clinical outcomes of sepsis. This study was aimed to investigate whether the associations between the vital signs and mortalit...
Citation: Critical Care 2020 24:387 -
Hospital preparedness for mass critical care during SARS-CoV-2 pandemic
Mass critical care caused by the severe acute respiratory syndrome corona virus 2 pandemic poses an extreme challenge to hospitals. The primary goal of hospital disaster preparedness and response is to maintai...
Citation: Critical Care 2020 24:386 -
Brain tight junction protein expression in sepsis in an autopsy series
Neuroinflammation often develops in sepsis along with increasing permeability of the blood-brain barrier (BBB), which leads to septic encephalopathy. The barrier is formed by tight junction structures between ...
Citation: Critical Care 2020 24:385 -
Long-term survival of elderly patients after intensive care unit admission for acute respiratory infection: a population-based, propensity score-matched cohort study
Intensive care unit (ICU) hospitalisations of elderly patients with acute respiratory infection have increased, yet the long-term effects of ICU admission among elderly individuals remain unknown. We examined ...
Citation: Critical Care 2020 24:384 -
Update of the treatment of nosocomial pneumonia in the ICU
In accordance with the recommendations of, amongst others, the Surviving Sepsis Campaign and the recently published European treatment guidelines for hospital-acquired pneumonia (HAP) and ventilator-associated pn...
Citation: Critical Care 2020 24:383 -
Biofilm formation on three different endotracheal tubes: a prospective clinical trial
Biofilm formation on endotracheal tubes (ETTs) is an early and frequent event in mechanically ventilated patients. The biofilm is believed to act as a reservoir for infecting microorganisms and thereby contrib...
Citation: Critical Care 2020 24:382 -
Italian pulmonologist units and COVID-19 outbreak: “mind the gap”!
Citation: Critical Care 2020 24:381 -
Platelet-derived exosomes promote neutrophil extracellular trap formation during septic shock
Platelets have been demonstrated to be potent activators of neutrophil extracellular trap (NET) formation during sepsis. However, the mediators and molecular pathways involved in human platelet-mediated NET ge...
Citation: Critical Care 2020 24:380 -
Multimodal non-invasive assessment of intracranial hypertension: an observational study
Although placement of an intra-cerebral catheter remains the gold standard method for measuring intracranial pressure (ICP), several non-invasive techniques can provide useful estimates. The aim of this study ...
Citation: Critical Care 2020 24:379 -
Usefulness of point-of-care multiplex PCR to rapidly identify pathogens responsible for ventilator-associated pneumonia and their resistance to antibiotics: an observational study
The use of multiplex PCR to shorten time to identification of pathogens and their resistance mechanisms for patients with ventilator-associated pneumonia (VAP) is attractive, but poorly studied. The multiplex ...
Citation: Critical Care 2020 24:378 -
Correction to: The role of high load herpes simplex virus in patients with mechanical ventilation: a real hospital acquired viral lung infection needs antiviral therapy?
An amendment to this paper has been published and can be accessed via the original article.
Citation: Critical Care 2020 24:377 -
Mobilization practices in critically ill children: a European point prevalence study (EU PARK-PICU)
Early mobilization of adults receiving intensive care improves health outcomes, yet little is known about mobilization practices in paediatric intensive care units (PICUs). We aimed to determine the prevalence...
Citation: Critical Care 2020 24:368 -
Correction to: The effect of corticosteroids on the mortality of patients with influenza pneumonia: a systematic review and meta-analysis
An amendment to this paper has been published and can be accessed via the original article.
Citation: Critical Care 2020 24:376 -
COVID-19: ICU delirium management during SARS-CoV-2 pandemic—pharmacological considerations
Citation: Critical Care 2020 24:375 -
Correction to: How to measure blood pressure using an arterial catheter: a systematic 5-step approach
An amendment to this paper has been published and can be accessed via the original article.
Citation: Critical Care 2020 24:374 -
VEGF-D: a novel biomarker for detection of COVID-19 progression
Citation: Critical Care 2020 24:373 -
Learning from cubism to understand the reality of hemodynamics
Citation: Critical Care 2020 24:372 -
Protocol for awake prone positioning in COVID-19 patients: to do it earlier, easier, and longer
Citation: Critical Care 2020 24:371 -
Preventive use of respiratory support after scheduled extubation in critically ill medical patients—a network meta-analysis of randomized controlled trials
Respiratory support has been increasingly used after extubation for the prevention of re-intubation and improvement of prognosis in critically ill medical patients. However, the optimal respiratory support met...
Citation: Critical Care 2020 24:370 -
Using indirect calorimetry in place of fixed energy prescription was feasible and energy targets were more closely met: do not forget an important limitation
Citation: Critical Care 2020 24:369 -
Screening for low testosterone is needed for early identification and treatment of men at high risk of mortality from Covid-19
Citation: Critical Care 2020 24:367 -
Performance and impact of a multiplex PCR in ICU patients with ventilator-associated pneumonia or ventilated hospital-acquired pneumonia
Early appropriate antibiotic therapy reduces morbidity and mortality of severe pneumonia. However, the emergence of bacterial resistance requires the earliest use of antibiotics with the narrowest possible spe...
Citation: Critical Care 2020 24:366 -
“War to the knife” against thromboinflammation to protect endothelial function of COVID-19 patients
In this viewpoint, we summarize the relevance of thromboinflammation in COVID-19 and discuss potential mechanisms of endothelial injury as a key point for the development of lung and distant organ dysfunction,...
Citation: Critical Care 2020 24:365 -
Prevention of thrombotic risk in hospitalized patients with COVID-19 and hemostasis monitoring
COVID-19 is an infection induced by the SARS-CoV-2 coronavirus, and severe forms can lead to acute respiratory distress syndrome (ARDS) requiring intensive care unit (ICU) management. Severe forms are associat...
Citation: Critical Care 2020 24:364 -
First do no harm—beware the risk of therapeutic plasma exchange in severe COVID-19
Citation: Critical Care 2020 24:363 -
High doses of ketamine to improve neuronal edema in subarachnoid hemorrhage: we should consider other undesirable organ targets
Citation: Critical Care 2020 24:362 -
Bedside rapid placement of nasointestinal feeding tube via ultrasound-guided stylet positioning in critical COVID-19 patients
Citation: Critical Care 2020 24:361 -
Compassionate use of others’ immunity — understanding gut microbiome in Covid-19
Citation: Critical Care 2020 24:358 -
Single ventilator for multiple patients during COVID19 surge: matching and balancing patients
Citation: Critical Care 2020 24:357
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- ISSN: 1364-8535 (electronic)