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This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
This article is part of a Supplement: Volume 14 Supplement 2
Prone ventilation (PV) is a ventilatory strategy that frequently improves oxygenation and lung mechanics in critical illness, yet does not consistently improve survival. While the exact physiologic mechanisms ...
The Intra-Aortic Balloon Pump (IABP) is frequently used to mechanically support the heart. There is evidence that IABP improves microvascular flow during cardiogenic shock but its influence on the human microc...
Prevention of iatrogenic injury due to ventilation of a heterogeneous lung requires knowledge of dynamic regional events occurring within the tidal cycle. Quantitative bedside imaging techniques that are sensi...
Human cells require O2 for their energy supply, and critical illness can threaten the efficient delivery of O2 in accordance with tissue metabolic needs. In the accompanying article, Martin and colleagues point o...
Systemic inflammation in sepsis is initiated by interactions between pathogen molecular motifs and specific host receptors, especially toll-like receptors (TLRs). Flagellin is the main flagellar protein of mot...
Sepsis is a serious medical condition that requires rapidly administered, appropriate antibiotic treatment. Conventional methods take three or more days for final pathogen identification and antimicrobial susc...
Appropriate timing of treatment assumes particular importance in critical care. Lange and colleagues recently reported on the time course of the different nitric oxide synthase (NOS) isoforms, nitrosative stre...
Gas6, the protein product of the growth arrest specific gene 6, is present in human circulation at subnanomolar concentrations. It is secreted by endothelial cells and is important for the activation of endoth...
Aneurysmal subarachnoid hemorrhage (SAH) affects relatively young people and carries a poor prognosis with a case fatality rate of 35%. One of the major systemic complications associated with SAH is acute lung...
The physiological response to blood glucose elevation is the pancreatic release of insulin, which blocks hepatic glucose production and release, and stimulates glucose uptake and storage in insulin-dependent t...
Critical Care