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Measuring extravascular lung water may be useful for predicting outcome in adults with acute lung injury. The present commentary briefly reviews the potential role and limitations of extravascular lung water m...
This article is part of a Supplement: Volume 16 Supplement 1
Recent years have seen the place of the pulmonary artery catheter in intensive care increasingly challenged, with one recent study reporting no difference in outcome in patients treated with or without a pulmo...
Sterile or non-infectious inflammation and severe infection are accompanied by very similar events. Damage (or danger)-associated molecular patterns and pathogen-associated molecular patterns trigger the relea...
This article is part of a Supplement: Volume 18 Supplement 2
Intensive monitoring and aggressive management of perioperative haemodynamics (goal directed therapy) have repeatedly been reported to reduce the significant morbidity and mortality associated with high risk s...
Thrombocytopenia is a common finding in critically ill patients. Heparin-induced thrombocytopenia is an infrequent cause of a low platelet count. Intensivists should use the diagnostic classification system de...
Description of all consecutive critically ill COVID 19 patients hospitalized in ICU in University Hospital of Guadeloupe and outcome according to delay between steroid therapy initiation and mechanical ventila...
The Correspondence to this article has been published in Critical Care 2022 26:212
The composition and function of intestinal microflora are emerging as integral to both health and disease. During critical illness the normal microbiota are rapidly replaced by pathogenic species as a result o...
The original article was published in Critical Care 2023 27:275
No abstract.
Multilumen catheters are commonly used in critically ill children.Their use, however, is associated with significant morbidity. We studied thesimultaneous administration of incompatible drugs using a new tripl...
The original article was published in Critical Care 2022 26:272
The Correspondence to this article has been published in Critical Care 2022 26:388
The original article was published in Critical Care 2021 25:189
This article is part of a Supplement: Volume 16 Supplement 2
Myocardial infarction remains a major cause of death despite contemporary therapeutic strategies. Diagnosis in the intensive care unit is challenging, but is essential to target therapy accurately. In this iss...
Intensivists depend upon a large number of measurements to make daily decisions in the ICU. However, the reliability of these measures may be jeopardized by the effects of therapy. Moreover, in critical illnes...
The original article was published in Critical Care 2024 28:32
The original article was published in Critical Care 2024 28:67
Dynamic predictors are clearly superior to static pressures in predicting whether a patient will respond to a fluid bolus. Hand-carried ultrasound (HCUS) can measure changes in blood flow velocity in the brach...
This article is part of a Supplement: Volume 15 Supplement 3
Acute lung injury is a syndrome of inflammation and of increased permeability of the blood–gas barrier. Endothelins are thought to exert proinflammatory effects. Kuklin and colleagues show that the endothelin ...
Clinicians depend on recognizing particular critical illnesses (such as sepsis and cardiac failure) from patterns of vital...
Shock therapy aims at increasing central venous oxygen saturation (ScvO2), which is a marker of inadequate oxygen delivery. In this issue of Critical Care, Textoris and colleagues challenge this notion by reporti...
Monitoring tissue hypoxia in critically ill patients is a challenging task. Tissue PCO2 has long been proposed as a marker of tissue hypoxia, although there is considerable controversy on whether the rise in CO2 ...
The original article was published in Critical Care 2024 28:41
Combining therapeutic doses of low-molecular-weight heparins and increasing doses of recombinant activated protein C - Drotrecogin alpha (activated), or DAA - is of theoretical interest with regard to the cont...
This article is part of a Supplement: Volume 13 Supplement 3
The replacement, refinement, and reduction (3Rs) guidelines are the cornerstone of animal welfare practice for medical research. Nowadays, no animal research can be performed without being approved by an anima...
The Letter to this article has been published in Critical Care 2021 25:422
Acute kidney injury has become a major focus for nephrologists and critical care physicians. The development of structural biomarkers is proceeding, but the results to date have been disappointing. The use of ...
In a previous issue of Critical Care, Schilder and colleagues report the results of their multicenter trial (Citrate Anticoagulation Versus Systemic Heparinization; CASH) comparing regional anticoagulation with c...
Critical Care