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  1. The present paper describes the methods of data collection and validation employed in the Intensive Care National Audit & Research Centre Case Mix Programme (CMP), a national comparative audit of outcome for a...

    Authors: David A Harrison, Anthony R Brady and Kathy Rowan
    Citation: Critical Care 2004 9(Suppl 3):S1
    Content type: Research Published on:

    This article is part of a Supplement: Volume 9 Supplement 3

  2. Coronary artery disease remains a common problem in industrialized countries. Percutaneous coronary interventions are usually performed utilizing the femoral approach. Arterial puncture-closing devices have be...

    Authors: Joseph Varon and Robert E Fromm Jr
    Citation: Critical Care 2004 8:87
    Content type: Commentary Published on:

  3. The objective of the present study was to compare the health-related quality of life (HR-QoL) of survivors from severe sepsis and septic shock with HR-QoL in others who survived critical illness not involving ...

    Authors: Cristina Granja, Cláudia Dias, Altamiro Costa-Pereira and António Sarmento
    Citation: Critical Care 2004 8:R91
    Content type: Research Published on:

  7. Most hospitals are facing the dilemma caused by demand for critical care beds outstripping supply. This imbalance is likely to get worse over the coming years as a result of many factors, including aging of th...

    Authors: David Crippen and Laura Hawryluck
    Citation: Critical Care 2004 8:231
    Content type: Review Published on:

  8. Antibiotic-resistant bacteria are an increasingly common problem in intensive care units (ICUs), and they are capable of impacting on patient outcome, the ICU's budget and bed availability. This issue, coupled...

    Authors: Barry M Farr and Geoffrey Bellingan
    Citation: Critical Care 2004 8:153
    Content type: Review Published on:

  10. Acid–base disorders are common in critically ill patients. Metabolic acid–base disorders are particularly common in patients who require acute renal replacement therapy. In these patients, metabolic acidosis i...

    Authors: Toshio Naka and Rinaldo Bellomo
    Citation: Critical Care 2004 8:108
    Content type: Review Published on:

  14. Sepsis almost invariably leads to hemostatic abnormalities, ranging from insignificant laboratory changes to severe disseminated intravascular coagulation. There is compelling evidence from clinical and experi...

    Authors: Marcel Levi and Tom van der Poll
    Citation: Critical Care 2004 8:99
    Content type: Commentary Published on:

  15. PROWESS (Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis) was a phase III, randomized, double blind, placebo controlled, multicenter trial conducted in patients with severe sepsis f...

    Authors: Gary T Kinasewitz, S Betty Yan, Bruce Basson, Philip Comp, James A Russell, Alain Cariou, Suzane L Um, Barbara Utterback, Pierre-Francois Laterre and Jean-François Dhainaut
    Citation: Critical Care 2004 8:R82
    Content type: Research Published on:

  16. Acute hypoxic respiratory failure (AHRF) remains a significant cause of death in intensive care units. With the realization that pathophysiologic abnormalities in AHRF involve surfactant abnormalities as well ...

    Authors: Shonola S Da-Silva and R Phillip Dellinger
    Citation: Critical Care 2004 8:77
    Content type: Commentary Published on:

  18. The decision to withdraw or withhold life supporting treatment in moribund patients is difficult under any circumstances. When the patient becomes incompetent to clarify their wishes regarding continued mainte...

    Authors: Tom Buckley, David Crippen, Anthony L DeWitt, Malcolm Fisher, Antonios Liolios, Christine L Scheetz and Leslie M Whetstine
    Citation: Critical Care 2004 8:79
    Content type: Commentary Published on:

  24. N-acetylcysteine (NAC) has been shown to improve splanchnic blood flow in experimental studies. This report evaluates the effects of NAC on liver perfusion and lactate signal intensities in the liver tissue of .....

    Authors: Ortrud Vargas Hein, Renate Öhring, Andreas Schilling, Michael Oellerich, Victor W Armstrong, Wolfgang J Kox and Claudia Spies
    Citation: Critical Care 2004 8:R66
    Content type: Research Published on:

  33. The organs of the hepatosplanchnic system are considered to play a key role in the development of multiorgan failure during septic shock. Impaired oxygenation of the intestinal mucosa can lead to disruption of...

    Authors: Pierre Asfar, Daniel De Backer, Andreas Meier-Hellmann, Peter Radermacher and Samir G Sakka
    Citation: Critical Care 2003 8:170
    Content type: Review Published on:

  36. The aims of the present study were to assess patients' memories of their stay in the intensive care unit (ICU) over time, using the Italian version of the ICU Memory (ICUM) tool, and to examine the relationshi...

    Authors: Maurizia Capuzzo, Vanna Valpondi, Emiliano Cingolani, Serena De Luca, Giovanna Gianstefani, Luigi Grassi and Raffaele Alvisi
    Citation: Critical Care 2003 8:R48
    Content type: Research Published on:

  37. Antibiotics used for treatment of severe bacterial infections have been shown to exert effects on the inflammatory response in addition to their antibacterial effects. The aim of the present study was to inves...

    Authors: Gunilla Goscinski, Miklos Lipcsey, Mats Eriksson, Anders Larsson, Eva Tano and Jan Sjölin
    Citation: Critical Care 2003 8:R35
    Content type: Research Published on:

  39. The intensive care unit is burdened with a high frequency of nosocomial infections often caused by multiresistant nosocomial pathogens. Coagulase-negative staphylococci (CoNS) are reported to be the third caus...

    Authors: Christina Agvald-Öhman, Bodil Lund and Charlotta Edlund
    Citation: Critical Care 2003 8:R42
    Content type: Research Published on:

  41. In August 2003, France sustained an unprecedented heat wave that resulted in 14,800 excess deaths. The consequences were maximal in the Paris area. The Assistance Publique–Hôpitaux de Paris reported more than ...

    Authors: Jean-François Dhainaut, Yann-Erick Claessens, Christine Ginsburg and Bruno Riou
    Citation: Critical Care 2003 8:1
    Content type: Commentary Published on:

  44. This open label, multicentre study was conducted to assess the times to offset of the pharmacodynamic effects and the safety of remifentanil in patients with varying degrees of renal impairment requiring inten...

    Authors: Des Breen, Alexander Wilmer, Andrew Bodenham, Vagn Bach, Jan Bonde, Paul Kessler, Sven Albrecht and Soraya Shaikh
    Citation: Critical Care 2003 8:R21
    Content type: Research Published on:

  45. Procalcitonin (PCT) has been proposed as a marker of infection in critically ill patients; its level is related to the severity of infection. We evaluated the value of PCT as a marker of bacterial infection fo...

    Authors: Yi-Ling Chan, Ching-Ping Tseng, Pei-Kuei Tsay, Shy-Shin Chang, Te-Fa Chiu and Jih-Chang Chen
    Citation: Critical Care 2003 8:R12
    Content type: Research Published on:

  46. This double-blind, randomized, multicentre study was conducted to compare the efficacy and safety of remifentanil and fentanyl for intensive care unit (ICU) sedation and analgesia.

    Authors: Bernd Muellejans, Angel López, Michael H Cross, César Bonome, Lachlan Morrison and Andrew JT Kirkham
    Citation: Critical Care 2003 8:R1
    Content type: Research Published on:

  48. The contribution by Pepe and colleagues provides additional evidence that initial defibrillation is not necessarily the optimal intervention for victims of cardiac arrest and especially when cardiac arrest has...

    Authors: Max Harry Weil and Wanchun Tang
    Citation: Critical Care 2003 8:11
    Content type: Commentary Published on:
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  • ISSN: 1364-8535 (electronic)

Critical Care

ISSN: 1364-8535