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  1. The pulmonary artery catheter (PAC) was introduced in 1971 for the assessment of heart function at the bedside. Since then it has generated much enthusiasm and controversy regarding the benefits and potential ...

    Authors: Mehrnaz Hadian and Michael R Pinsky
    Citation: Critical Care 2006 10(Suppl 3):S8

    This article is part of a Supplement: Volume 10 Supplement 3

  2. Right ventricular failure (RVF) is an underestimated problem in intensive care. This review explores the physiology and pathophysiology of right ventricular function and the pulmonary circulation. When RVF is ...

    Authors: Maurizio Cecconi, Edward Johnston and Andrew Rhodes
    Citation: Critical Care 2006 10(Suppl 3):S5

    This article is part of a Supplement: Volume 10 Supplement 3

  3. The usefulness of parameters measured using the pulmonary artery catheter has been challenged because no benefit in patient outcome has been observed in clinical trials. However, technological advances have be...

    Authors: Emmanuel Robin, Marion Costecalde, Gilles Lebuffe and Benoît Vallet
    Citation: Critical Care 2006 10(Suppl 3):S3

    This article is part of a Supplement: Volume 10 Supplement 3

  4. Cardiac surgery with cardiopulmonary bypass (CPB) is associated with the activation of inflammatory mediators that possess prothrombotic activity and could cause postoperative haemostatic disorders. This study...

    Authors: Ruth Heying, Wim van Oeveren, Stefanie Wilhelm, Katharina Schumacher, Ralph G Grabitz, Bruno J Messmer and Marie-Christine Seghaye
    Citation: Critical Care 2006 10:R165
  5. Cardiac output (CO) monitoring is indicated only in selected patients. In cardiac surgical patients, perioperative haemodynamic management is often guided by CO measurement by pulmonary artery catheterisation (CO

    Authors: Michael Sander, Claudia D Spies, Herko Grubitzsch, Achim Foer, Marcus Müller and Christian von Heymann
    Citation: Critical Care 2006 10:R164
  6. Little is known about the condition of the large bowel in patients with sepsis. We have previously demonstrated increased concentrations of L-lactate in the rectal lumen in patients with abdominal septic shock. T...

    Authors: Vibeke L Jørgensen, Nanna Reiter and Anders Perner
    Citation: Critical Care 2006 10:R163
  7. Central venous cannulation is crucial in the management of the critical care patient. This study was designed to evaluate whether real-time ultrasound-guided cannulation of the internal jugular vein is superio...

    Authors: Dimitrios Karakitsos, Nicolaos Labropoulos, Eric De Groot, Alexandros P Patrianakos, Gregorios Kouraklis, John Poularas, George Samonis, Dimosthenis A Tsoutsos, Manousos M Konstadoulakis and Andreas Karabinis
    Citation: Critical Care 2006 10:R162
  8. Heparin-induced thrombocytopenia (HIT) is described as a decrease in platelet count associated with heparin administration and is an immune-mediated adverse drug reaction that can cause both arterial and venou...

    Authors: Elise M Gettings, Kathryn A Brush, Elizabeth M Van Cott and William E Hurford
    Citation: Critical Care 2006 10:R161
  9. Cognitive dysfunction is common in critically ill patients, not only during the acute illness but also long after its resolution. A large number of pathophysiologic mechanisms are thought to underlie critical ...

    Authors: Eric B Milbrandt and Derek C Angus
    Citation: Critical Care 2006 10:238
  10. Sepsis activates the coagulation system and frequently causes hypercoagulability, which is not detected by routine coagulation tests. A reliable method to evaluate hypercoagulability is thromboelastography (TE...

    Authors: Christopher Gonano, Christian Sitzwohl, Eva Meitner, Christian Weinstabl and Stephan C Kettner
    Citation: Critical Care 2006 10:R160
  11. Neurologic disability is a feared outcome of resuscitation from cardiac arrest. The study by Rech and colleagues in the previous issue of Critical Care describes the use of neuron-specific enolase to inform an ea...

    Authors: David Tirschwell
    Citation: Critical Care 2006 10:171
  12. The purpose of this study was to determine if noninvasive transcranial oxygen saturation (StcO2) and Bispectral Index (BIS) correlate with severe traumatic brain injury intensive care unit (ICU) outcomes.

    Authors: Michael Dunham, Kenneth J Ransom, Clyde E McAuley, Brian S Gruber, Dev Mangalat and Laurie L Flowers
    Citation: Critical Care 2006 10:R159
  13. Successful treatment of severe sepsis and septic shock remains a major challenge in critical care medicine. The recently introduced recombinant human activated protein C (APC) remarkably improved the outcome o...

    Authors: Christian Lehmann, Konrad Meissner, Andreas Knöck, Stephan Diedrich, Dragan Pavlovic, Matthias Gründling, Taras Usichenko, Michael Wendt and Jürgen Birnbaum
    Citation: Critical Care 2006 10:R157
  14. A major issue raised by the public health consequences of a heat wave is the difficulty of detecting its direct consequences on patient outcome, particularly because of the delay in obtaining definitive mortal...

    Authors: Yann-Erick Claessens, Pierre Taupin, Gérald Kierzek, Jean-Louis Pourriat, Michel Baud, Christine Ginsburg, Jean-Philippe Jais, Eric Jougla, Bruno Riou, Jean-François Dhainaut and Paul Landais
    Citation: Critical Care 2006 10:R156
  15. Apoptosis of neutrophils (polymorphonuclear neutrophils [PMNs]) may limit inflammatory injury in sepsis and acute respiratory distress syndrome (ARDS), but the relationship between the severity of sepsis and e...

    Authors: Léa Fialkow, Luciano Fochesatto Filho, Mary C Bozzetti, Adriana R Milani, Edison M Rodrigues Filho, Roberta M Ladniuk, Paula Pierozan, Rafaela M de Moura, João C Prolla, Eric Vachon and Gregory P Downey
    Citation: Critical Care 2006 10:R155
  16. New onset thrombocytopenia and multiple organ failure (TAMOF) presages poor outcome in critical illness. Patients who resolve thrombocytopenia by day 14 are more likely to survive than those who do not. Patien...

    Authors: Trung C Nguyen and Joseph A Carcillo
    Citation: Critical Care 2006 10:235
  17. Whereas most studies focus on laboratory and clinical research, little is known about the causes of death and risk factors for death in critically ill patients.

    Authors: Viktoria D Mayr, Martin W Dünser, Veronika Greil, Stefan Jochberger, Günter Luckner, Hanno Ulmer, Barbara E Friesenecker, Jukka Takala and Walter R Hasibeder
    Citation: Critical Care 2006 10:R154
  18. Nosocomial pneumonia is a major source of morbidity and mortality after severe burns. Burned patients suffer trace element deficiencies and depressed antioxidant and immune defences. This study aimed at determ...

    Authors: Mette M Berger, Philippe Eggimann, Daren K Heyland, René L Chioléro, Jean-Pierre Revelly, Andrew Day, Wassim Raffoul and Alan Shenkin
    Citation: Critical Care 2006 10:R153
  19. Heterotopic ossification (HO) is the formation of bone in soft tissues. The purpose of the present study was to evaluate the magnetic resonance imaging (MRI) findings on clinical suspicion of HO in the knee jo...

    Authors: Maria I Argyropoulou, Eleonora Kostandi, Paraskevi Kosta, Anastasia K Zikou, Dimitra Kastani, Efi Galiatsou, Athanassios Kitsakos and George Nakos
    Citation: Critical Care 2006 10:R152
  20. Extracorporeal lung assist, an extreme resource in patients with acute respiratory failure (ARF), is expanding its indications since knowledge about ventilator-induced lung injury has increased and protective ...

    Authors: Sergio Livigni, Mariella Maio, Enrica Ferretti, Annalisa Longobardo, Raffaele Potenza, Luca Rivalta, Paola Selvaggi, Marco Vergano and Guido Bertolini
    Citation: Critical Care 2006 10:R151
  21. Statin therapy may represent a potential prophylactic intervention in certain high-risk scenarios, for example in pandemic influenza and in those undergoing aggressive medical treatments. Emerging data indicat...

    Authors: Marius Terblanche, Terry S Smith and Neill KJ Adhikari
    Citation: Critical Care 2006 10:168
  22. The mechanism of coagulation activation during continuous venovenous hemofiltration (CVVH) has not yet been elucidated. Insight into the mechanism(s) of hemostatic activation within the extracorporeal circuit ...

    Authors: Catherine SC Bouman, Anne-Cornélie JM de Pont, Joost CM Meijers, Kamran Bakhtiari, Dorina Roem, Sacha Zeerleder, Gertjan Wolbink, Johanna C Korevaar, Marcel Levi and Evert de Jonge
    Citation: Critical Care 2006 10:R150
  23. Adrenal failure (AF) is associated with increased mortality in septic patients. Nonetheless, there is no agreement regarding the best diagnostic criteria for AF. We compared the diagnosis of AF considering dif...

    Authors: Diamantino Ribeiro Salgado, Juan Carlos Rosso Verdeal and José Rodolfo Rocco
    Citation: Critical Care 2006 10:R149
  24. Hypothermia during sepsis significantly impairs patient outcome in clinical practice. Severe sepsis is closely linked to activation of the coagulation system, resulting in microthrombosis and subsequent organ ...

    Authors: Nicole Lindenblatt, Michael D Menger, Ernst Klar and Brigitte Vollmar
    Citation: Critical Care 2006 10:R148
  25. We investigated health-related quality of life (HRQoL) and persistent symptoms of post-traumatic stress disorder (PTSD) in long-term survivors of acute respiratory distress syndrome (ARDS). We wished to evalua...

    Authors: Maria Deja, Claudia Denke, Steffen Weber-Carstens, Jürgen Schröder, Christian E Pille, Frank Hokema, Konrad J Falke and Udo Kaisers
    Citation: Critical Care 2006 10:R147
  26. Critically ill patients suffer from oxidative stress caused by reactive oxygen species (ROS) and reactive nitrogen species (RNS). Although ROS/RNS are constantly produced under normal circumstances, critical i...

    Authors: Jimena Abilés, Antonio Pérez de la Cruz, José Castaño, Manuel Rodríguez-Elvira, Eduardo Aguayo, Rosario Moreno-Torres, Juan Llopis, Pilar Aranda, Sandro Argüelles, Antonio Ayala, Alberto Machado de la Quintana and Elena Maria Planells
    Citation: Critical Care 2006 10:R146
  27. Systemic inflammatory response syndrome is common after surgery, and it can be difficult to discriminate between infection and inflammation. We performed a review of the literature with the aims of describing ...

    Authors: Christoph Sponholz, Yasser Sakr, Konrad Reinhart and Frank Brunkhorst
    Citation: Critical Care 2006 10:R145
  28. This report describes the case mix and outcome (mortality, intensive care unit (ICU) and hospital length of stay) for admissions to ICU for head injury and evaluates the predictive ability of five risk adjustm...

    Authors: Jonathan A Hyam, Catherine A Welch, David A Harrison and David K Menon
    Citation: Critical Care 2006 10(Suppl 2):S2

    This article is part of a Supplement: Volume 10 Supplement 2

  29. Arginine vasopressin (AVP) is increasingly used to treat sepsis-related vasodilation and to decrease catecholamine requirements. However, AVP infusion may be associated with a marked decrease in systemic blood...

    Authors: Christian Ertmer, Andrea Morelli, Hans-Georg Bone, Henning Dirk Stubbe, Ralf Schepers, Hugo Van Aken, Matthias Lange, Katrin Bröking, Martin Lücke, Daniel L Traber and Martin Westphal
    Citation: Critical Care 2006 10:R144
  30. The aim of this study was to determine incidence, risk factors, and impact on outcome of intensive care unit (ICU)-acquired Stenotrophomonas maltophilia.

    Authors: Saad Nseir, Christophe Di Pompeo, Hélène Brisson, Florent Dewavrin, Stéphanie Tissier, Maimouna Diarra, Marie Boulo and Alain Durocher
    Citation: Critical Care 2006 10:R143
  31. Respiratory viruses are a major cause of respiratory tract infections. The prevalence of a virus-positive respiratory sample and its significance in patients requiring mechanical ventilation remain unknown.

    Authors: Cédric Daubin, Jean-Jacques Parienti, Sophie Vincent, Astrid Vabret, Damien du Cheyron, Michel Ramakers, François Freymuth and Pierre Charbonneau
    Citation: Critical Care 2006 10:R142