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Citation: Critical Care 2008 12:413
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Delirium assessment in the intensive care unit: patient population matters
The high prevalence and pervasive impact of delirium in critically ill patients has been demonstrated in multiple studies. Subsequently there has grown a body of literature regarding delirium assessment in cri...
Citation: Critical Care 2008 12:131 -
The pursuit of a high central venous oxygen saturation in sepsis: growing concerns
In this issue of Critical Care, Dutch investigators report that, in a cohort of patients with sepsis/septic shock admitted to three different intensive care units (ICUs), low central venous oxygen saturation (Scv...
Citation: Critical Care 2008 12:130 -
Introduction of Medical Emergency Teams in Australia and New Zealand: a multi-centre study
Information about Medical Emergency Teams (METs) in Australia and New Zealand (ANZ) is limited to local studies and a cluster randomised controlled trial (the Medical Emergency Response and Intervention Trial ...
Citation: Critical Care 2008 12:R46 -
Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated)
Drotrecogin alfa (activated; DrotAA) treatment, a 96-hour infusion, reduces 28-day mortality in severe sepsis to approximately 25%. The question remains whether a longer infusion or higher dose could increase ...
Citation: Critical Care 2008 12:R45 -
Discriminating invasive fungal infection from colonization
Citation: Critical Care 2008 12:412 -
Myocardial infarction on the ICU: can we do better?
Myocardial infarction remains a major cause of death despite contemporary therapeutic strategies. Diagnosis in the intensive care unit is challenging, but is essential to target therapy accurately. In this iss...
Citation: Critical Care 2008 12:129 -
Risk factors for the development of nosocomial pneumonia and mortality on intensive care units: application of competing risks models
Pneumonia is a very common nosocomial infection in intensive care units (ICUs). Many studies have investigated risk factors for the development of infection and its consequences. However, the evaluation in mos...
Citation: Critical Care 2008 12:R44 -
Danaparoid sodium inhibits systemic inflammation and prevents endotoxin-induced acute lung injury in rats
Systemic inflammatory mediators, including high mobility group box 1 (HMGB1), play an important role in the development of sepsis. Anticoagulants, such as danaparoid sodium (DA), may be able to inhibit sepsis-...
Citation: Critical Care 2008 12:R43 -
Clinical review: Airway hygiene in the intensive care unit
Maintenance of airway secretion clearance, or airway hygiene, is important for the preservation of airway patency and the prevention of respiratory tract infection. Impaired airway clearance often prompts admi...
Citation: Critical Care 2008 12:209 -
Tracheostomy decannulation: marathons and finish lines
Critically ill patients with a tracheostomy who are recovering from respiratory failure eventually require evaluation for airway decannulation. Although expert recommendations guide decisions for managing deca...
Citation: Critical Care 2008 12:128 -
Pulmonary artery occlusion pressure estimation by transesophageal echocardiography: is simpler better?
The measurement of pulmonary artery occlusion pressure (PAOP) is important for estimation of left ventricular filling pressure and for distinction between cardiac and non-cardiac etiology of pulmonary edema. C...
Citation: Critical Care 2008 12:127 -
Circulating pro-apoptotic mediators in burn septic acute renal failure
The pathogenesis of septic acute kidney injury (AKI) is not well understood. In the present issue of Critical Care, the combined clinical and experimental study from Mariano's group provides new insight into the ...
Citation: Critical Care 2008 12:126 -
Knowing who would respond to a recruitment maneuver before actually doing it – this might be a way to go
Using recruitment manoeuvres in acute lung injury remains a controversial issue because no convincing outcome data support their general use, although many physiological studies have demonstrated beneficial ef...
Citation: Critical Care 2008 12:125 -
Insulin, intracerebral glucose and bedside biochemical monitoring utilizing microdialysis
Following subarachnoid hemorrhage, hyperglycemia is strongly associated with complications and with impaired neurological recovery. Targeted insulin therapy for glycemic control might, on the contrary, have ha...
Citation: Critical Care 2008 12:124 -
Optimal vasopressor drug therapy during resuscitation
Optimal vasopressor support during resuscitation should theoretically enhance aortic diastolic and coronary perfusion pressure as well as coronary and cerebral blood flow/oxygen delivery without increasing cel...
Citation: Critical Care 2008 12:123 -
Lost in translation? The pursuit of lung-protective ventilation
Acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) remain important causes of morbidity and mortality in the critically ill patient, with far-reaching short-term and long-term implicati...
Citation: Critical Care 2008 12:122 -
KL-6 in acute lung injury: will it leave its mark?
Studies have indicated that measuring biochemical measures of epithelial injury in plasma and alveolar fluid may be useful in predicting outcome in acute lung injury. The present commentary briefly reviews the...
Citation: Critical Care 2008 12:121 -
Recently published papers: Sepsis – guidelines, treatment and novel approaches
The choice of inotropic agent, particularly in catecholamine-resistant septic shock, remains an area of debate. Here we discuss a recent trial examining the use of vasopressin in a carefully controlled trial s...
Citation: Critical Care 2008 12:120 -
Circulating plasma factors induce tubular and glomerular alterations in septic burns patients
Severe burn is a systemic illness often complicated by sepsis. Kidney is one of the organs invariably affected, and proteinuria is a constant clinical finding. We studied the relationships between proteinuria ...
Citation: Critical Care 2008 12:R42 -
Biomarkers of inflammation, coagulation and fibrinolysis predict mortality in acute lung injury
Acute lung injury (ALI) is a major cause of acute respiratory failure with high mortality despite lung-protective ventilation. Prior work has shown disordered inflammation and coagulation in ALI, with strong c...
Citation: Critical Care 2008 12:R41 -
Towards goal-directed therapy of hepatorenal syndrome: we have the tools but we need the trials
Patients with cirrhosis who develop tense ascites and hepatorenal syndrome have a very high mortality and present a management challenge. Current debate stems from a lack of studies evaluating changes in effec...
Citation: Critical Care 2008 12:119 -
Cardiovascular and metabolic responses to catecholamine and sepsis prognosis: a ubiquitous phenomenon?
Many parameters have been associated with sepsis prognosis. In the present issue of Critical Care, Kumar and colleagues demonstrate that a preserved cardiac answer to dobutamine evaluated by radionucleotide measu...
Citation: Critical Care 2008 12:118 -
Vasopressin and epinephrine in the treatment of cardiac arrest: an experimental study
Epinephrine remains the drug of choice for cardiopulmonary resuscitation. The aim of the present study is to assess whether the combination of vasopressin and epinephrine, given their different mechanisms of a...
Citation: Critical Care 2008 12:R40 -
Nicotine replacement therapy is associated with improved outcomes in critically ill smokers
Citation: Critical Care 2008 12(Suppl 2):P514 -
Initiation of renal replacement therapy in patients with acute kidney injury and severe lactic acidosis
Citation: Critical Care 2008 12(Suppl 2):P479 -
Serum urea as a marker for initiation of renal replacement therapy in ICU patients with acute kidney injury
Citation: Critical Care 2008 12(Suppl 2):P478 -
Serum measurement of N-terminal pro-brain peptide among septic patients
Citation: Critical Care 2008 12(Suppl 2):P443 -
Low cardiac function index predicts ICU mortality in patients with severe sepsis or septic shock
Citation: Critical Care 2008 12(Suppl 2):P410 -
Terlipressin in catecholamine-resistant hyperdynamic shock patients after cardiac surgery
Citation: Critical Care 2008 12(Suppl 2):P406 -
Use of hypothermia for out-of-hospital cardiac arrest survivors: a single-centre experience
Citation: Critical Care 2008 12(Suppl 2):P374 -
Etiology of prehospital cardiac arrest largely determines outcome in patients treated with mild hypothermia
Citation: Critical Care 2008 12(Suppl 2):P372 -
Tracheal wall pressures in the clinical setting: comparing Portex Soft Seal and Lotrach cuffs
Citation: Critical Care 2008 12(Suppl 2):P339 -
An audit of perioperative staffing and complications during percutaneous and surgical tracheostomy insertion
Citation: Critical Care 2008 12(Suppl 2):P335 -
Effect of positive end-expiratory pressure application on inflammation in acute respiratory distress syndrome patients during pressure–volume curve maneuver
Citation: Critical Care 2008 12(Suppl 2):P300 -
Pulmonary homogenicity changes during recruitment maneuvers and positive end-expiratory pressure in dogs with acute respiratory distress syndrome
Citation: Critical Care 2008 12(Suppl 2):P298 -
From low-tidal-volume ventilation to lowest-tidal-volume ventilation
Citation: Critical Care 2008 12(Suppl 2):P296 -
Hemodynamic effects of levosimendan in patients with low-output heart failure
Citation: Critical Care 2008 12(Suppl 2):P264 -
Haemodynamic effects of a fluid challenge with hydroxylethyl starch 130/0.4 (Voluven®) in patients suffering from symptomatic vasospasm after subarachnoid haemorrhage
Citation: Critical Care 2008 12(Suppl 2):P231 -
What is the efficacy of a filter needle in the retention of typical bacterial pathogens?
Citation: Critical Care 2008 12(Suppl 2):P227 -
Biochemical markers of the iron metabolism and their relationship with the inflammatory status in multiple trauma patients
Citation: Critical Care 2008 12(Suppl 2):P192 -
Measurement of procalcitonin in bronchoalveolar lavage and serum as early predictors in acute respiratory distress syndrome
Citation: Critical Care 2008 12(Suppl 2):P188 -
Intensive insulin therapy: protocols in use in The Netherlands
Citation: Critical Care 2008 12(Suppl 2):P160 -
Evaluation of the implementation of a fully automated algorithm (eMPC) in an interacting infusion pump system for the establishment of tight glycaemic control in medical ICU patients
Citation: Critical Care 2008 12(Suppl 2):P156 -
Brain trauma care targets analysis using a high-rate recording and computing network
Citation: Critical Care 2008 12(Suppl 2):P121 -
Noninvasive assessment of intracranial pressure using ocular sonography in neurocritical care patients
Citation: Critical Care 2008 12(Suppl 2):P117 -
Noninvasive rodent cardiac output: comparison of a compact clinical monitor with echocardiography and proposal of a simple correction factor
Citation: Critical Care 2008 12(Suppl 2):P84 -
Prebiotic, probiotic and synbiotic usage and gastrointestinal and trachea colonization in mechanically ventilated patients
Citation: Critical Care 2008 12(Suppl 2):P52 -
Effect of an oral care protocol in preventing ventilator-associated pneumonia in ICU patients
Citation: Critical Care 2008 12(Suppl 2):P48 -
Comparative study on infection of the central nervous system in patients with head trauma and spontaneous cerebral hemorrhage
Citation: Critical Care 2008 12(Suppl 2):P13
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- ISSN: 1364-8535 (electronic)