Articles
Page 179 of 376
-
Citation: Critical Care 2011 15:428
-
Using lung ultrasound to differentiate patients in acute dyspnea in the prehospital emergency setting
The diagnosis and treatment of dyspnea in the emergency department and in the prehospital setting is a challenge faced by the emergency physician and other prehospital care providers. While the use of lung ult...
Citation: Critical Care 2011 15:161 -
The conundrum of persistent inappropriate use of frozen plasma
Frozen plasma (FP) is commonly used for the treatment of bleeding or the prevention of bleeding in critically ill patients, but clinical evidence to help aid the critical care clinician make decisions on wheth...
Citation: Critical Care 2011 15:160 -
Hyperglycaemia and apoptosis of microglial cells in human septic shock
The effect of hyperglycaemia on the brain cells of septic shock patients is unknown. The objective of this study was to evaluate the relationship between hyperglycaemia and apoptosis in the brains of septic sh...
Citation: Critical Care 2011 15:R131 -
Intravenous magnesium in subarachnoid hemorrhage
Citation: Critical Care 2011 15:427 -
Care bundles: implementing evidence or common sense?
Care bundles aim to improve standard of care and patient outcome by promoting the consistent implementation of a group of effective interventions. However, a variety of barriers prevent their full application ...
Citation: Critical Care 2011 15:159 -
Insurance type and sepsis-associated hospitalizations and sepsis-associated mortality among US adults: A retrospective cohort study
Socio-demographic and clinical factors associated with increased sepsis risk, including older age, non-white race and specific co-morbidities, are more common among patients with Medicare or Medicaid or no hea...
Citation: Critical Care 2011 15:R130 -
Functional markers to predict the need for prolonged mechanical ventilation in patients with Guillain-Barré syndrome
Citation: Critical Care 2011 15:426 -
C-reactive protein in critically ill cancer patients with sepsis: influence of neutropenia
Several biomarkers have been studied in febrile neutropenia. Our aim was to assess C-reactive protein (CRP) concentration in septic critically ill cancer patients and to compare those with and without neutrope...
Citation: Critical Care 2011 15:R129 -
Effect of erythropoietin therapy on clinical outcome in patients after acute ischemic stroke: a debatable issue
Citation: Critical Care 2011 15:425 -
Multiple-center evaluation of mortality associated with acute kidney injury in critically ill patients: a competing risks analysis
In this study, we aimed to assess the association between acute kidney injury (AKI) and mortality in critically ill patients using an original competing risks approach.
Citation: Critical Care 2011 15:R128 -
The added value of ordinal analysis in clinical trials: an example in traumatic brain injury
In clinical trials, ordinal outcome measures are often dichotomized into two categories. In traumatic brain injury (TBI) the 5-point Glasgow outcome scale (GOS) is collapsed into unfavourable versus favourable...
Citation: Critical Care 2011 15:R127 -
Prone position and recruitment manoeuvre: the combined effect improves oxygenation
Among the various methods for improving oxygenation while decreasing the risk of ventilation-induced lung injury in patients with acute respiratory distress syndrome (ARDS), a ventilation strategy combining pr...
Citation: Critical Care 2011 15:R125 -
Injurious mechanical ventilation affects neuronal activation in ventilated rats
Survivors of critical illness often have significant long-term brain dysfunction, and routine clinical procedures like mechanical ventilation (MV) may affect long-term brain outcome. We aimed to investigate th...
Citation: Critical Care 2011 15:R124 -
Delayed diagnosis of tooth aspiration in three multiple trauma patients with mechanical ventilation
Citation: Critical Care 2011 15:424 -
Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: a historical control study
Cross-talk between the coagulation system and inflammatory reactions during sepsis causes organ damage followed by multiple organ dysfunction syndrome or even death. Therefore, anticoagulant therapies have bee...
Citation: Critical Care 2011 15:R123 -
Impact of routine percutaneous coronary intervention after out-of-hospital cardiac arrest due to ventricular fibrillation
Since 2003, we have routinely used percutaneous coronary intervention (PCI) and mild therapeutic hypothermia (MTH) to treat patients < 80 years of age after out-of-hospital cardiac arrest (OHCA) related to ven...
Citation: Critical Care 2011 15:R122 -
How natural light affects critically ill patients with subarachnoid hemorrhage
Citation: Critical Care 2011 15:423 -
Glucocorticoids in sepsis: dissecting facts from fiction
An intact hypothalamic-pituitary-adrenal (HPA) axis with effective intracellular glucocorticoid anti-inflammatory activity is essential for host survival following exposure to an infectious agent. Glucocortico...
Citation: Critical Care 2011 15:158 -
Bench-to-bedside review: Contrast enhanced ultrasonography - a promising technique to assess renal perfusion in the ICU
Acute kidney injury (AKI) is common in critically ill patients and associated with important morbidity and mortality. Although alterations in renal perfusion are thought to play a causative role in the pathoge...
Citation: Critical Care 2011 15:157 -
Deceased donor neutrophil gelatinase-associated lipocalin and delayed graft function after kidney transplantation: a prospective study
Expanding the criteria for deceased organ donors increases the risk of delayed graft function (DGF) and complicates kidney transplant outcome. We studied whether donor neutrophil gelatinase-associated lipocali...
Citation: Critical Care 2011 15:R121 -
Collapse-to-emergency medical service cardiopulmonary resuscitation interval and outcomes of out-of-hospital cardiopulmonary arrest: a nationwide observational study
The relationship between collapse to emergency medical service (EMS) cardiopulmonary resuscitation (CPR) interval and outcome has been well documented. However, most studies have only analyzed cases of cardiac...
Citation: Critical Care 2011 15:R120 -
Sedation and renal impairment in critically ill patients: a post hoc analysis of a randomized trial
Not sedating critically ill patients reduces the time patients receive mechanical ventilation, decreases the time in the intensive care department and reduces the total hospital length of stay. We hypothesized...
Citation: Critical Care 2011 15:R119 -
In critically ill patients the procalcitonin level can be misleading
Citation: Critical Care 2011 15:422 -
Positive end-expiratory pressure optimization with forced oscillation technique reduces ventilator induced lung injury: a controlled experimental study in pigs with saline lavage lung injury
Protocols using high levels of positive end-expiratory pressure (PEEP) in combination with low tidal volumes have been shown to reduce mortality in patients with severe acute respiratory distress syndrome (ARD...
Citation: Critical Care 2011 15:R126 -
Older patients in the ICU: a cautious analysis of epidemiologic data is required
Citation: Critical Care 2011 15:421 -
Diagnosis of invasive bronchial-pulmonary aspergillosis in patients with chronic obstructive respiratory diseases
Citation: Critical Care 2011 15:420 -
Distinction between induction and maintenance dosing in continuous renal replacement therapy
Citation: Critical Care 2011 15:419 -
Surfactant protein genetics in community-acquired pneumonia: balancing the host inflammatory state
Community-acquired pneumonia is a common disease. Abnormalities in the first step of host defense may severely compromise subsequent steps of successfully combating infections. In the previous issue of Critical C...
Citation: Critical Care 2011 15:156 -
Transpulmonary thermodilution for hemodynamic measurements in severely burned children
Monitoring of hemodynamic and volumetric parameters after severe burns is of critical importance. Pulmonary artery catheters, however, have been associated with many risks. Our aim was to show the feasibility ...
Citation: Critical Care 2011 15:R118 -
Clinical review: Adiponectin biology and its role in inflammation and critical illness
Adiponectin is an adipokine first described just over a decade ago. Produced almost exclusively by adipocytes, adiponectin circulates in high concentrations in human plasma. Research into this hormone has reve...
Citation: Critical Care 2011 15:221 -
Clinical review: Intrapericardial fibrinolysis in management of purulent pericarditis
Purulent pericarditis (PP) is a potentially life-threatening disease. Reported mortality rates are between 20 and 30%. Constrictive pericarditis occurs over the course of PP in at least 3.5% of cases. The freq...
Citation: Critical Care 2011 15:220 -
Controversies in acute kidney injury: the 2011 Brussels Roundtable
The recent advent of consensus definitions for acute kidney injury (AKI) has led to improvement in epidemiology of this complex disease and facilitated the development of new diagnostic makers and new therapie...
Citation: Critical Care 2011 15:155 -
How deficient are vitamin D deficient critically ill patients?
Vitamin D deficiency is highly prevalent among critically ill patients and may be associated with adverse outcomes. Failure of conventional vitamin D supplementation in correcting deficiency has called for stu...
Citation: Critical Care 2011 15:154 -
Erratum to: Early intra-intensive care unit psychological intervention promotes recovery from post traumatic stress disorders, anxiety and depression symptoms in critically ill patients
Citation: Critical Care 2011 15:418 -
Inspiratory muscle training in difficult to wean patients: work it harder, make it better, do it faster, makes us stronger
Weaning from prolonged mechanical ventilation is a complex, time-consuming process that involves the loss of force/generating capacity of the inspiratory muscle. In their study 'Inspiratory muscle strength tra...
Citation: Critical Care 2011 15:153 -
Blood transfusion and the lung: first do no harm?
Marked variability in transfusion practice exists in cardiac surgical patients, with consumption of approximately 20% of the worldwide allogeneic blood supply. Observational studies have reported an associatio...
Citation: Critical Care 2011 15:152 -
Therapeutic hypothermia post out-of-hospital cardiac arrest - more questions than answers?
Nearly a decade since the introduction of therapeutic hypothermia to the ICU for cooling out-of-hospital cardiac arrest patients, key questions remain unanswered: when should cooling be initiated, how rapidly ...
Citation: Critical Care 2011 15:151 -
High-dose tranexamic acid reduces blood loss in postpartum haemorrhage
Our purpose in conducting this study was to determine whether administration of high-dose tranexamic acid (TA) at the time of diagnosis of postpartum haemorrhage (PPH) could reduce blood loss.
Citation: Critical Care 2011 15:R117 -
Age of red blood cells and mortality in the critically ill
In critically ill patients, it is uncertain whether exposure to older red blood cells (RBCs) may contribute to mortality. We therefore aimed to evaluate the association between the age of RBCs and outcome in a...
Citation: Critical Care 2011 15:R116 -
Soluble triggering receptor on myeloid cells-1 is expressed in the course of non-infectious inflammation after traumatic lung contusion: a prospective cohort study
The triggering receptor expressed on myeloid cells-1 (TREM-1) is known to be expressed during bacterial infections. We investigated whether TREM-1 is also expressed in non-infectious inflammation following tra...
Citation: Critical Care 2011 15:R115 -
European legislation impedes critical care research and fails to protect patients' rights
The European Clinical Trials Directive requires an informed consent from the patient or a proxy in drug trials. Although informed consent is a valuable tool to protect patients' rights in clinical trials, this...
Citation: Critical Care 2011 15:148 -
Combination of lung ultrasound (a comet-tail sign) and N-terminal pro-brain natriuretic peptide in differentiating acute heart failure from chronic obstructive pulmonary disease and asthma as cause of acute dyspnea in prehospital emergency setting
We studied the diagnostic accuracy of bedside lung ultrasound (the presence of a comet-tail sign), N-terminal pro-brain natriuretic peptide (NT-proBNP) and clinical assessment (according to the modified Boston...
Citation: Critical Care 2011 15:R114 -
Thrombomodulin phenotype of a distinct monocyte subtype is an independent prognostic marker for disseminated intravascular coagulation
Thrombomodulin, which is expressed solely on monocytes, along with tissue factor (TF), takes part in coagulation and inflammation. Circulating blood monocytes can be divided into 3 major subtypes on the basis ...
Citation: Critical Care 2011 15:R113 -
Erratum to: Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials
Citation: Critical Care 2011 15:410 -
Why do pulse pressure variations fail to predict the response to fluids in acute respiratory distress syndrome patients ventilated with low tidal volume?
Respiratory-associated variations in stroke volume and pulse pressure are frequently used to predict the response to fluid administration. However, it has been demonstrated that low tidal volume ventilation ma...
Citation: Critical Care 2011 15:150 -
Impact of ureido/carboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to Pseudomonas aeruginosa
Although Pseudomonas aeruginosa is a leading pathogen responsible for ventilator-associated pneumonia (VAP), the excess in mortality associated with multi-resistance in patients with P. aeruginosa VAP (PA-VAP), t...
Citation: Critical Care 2011 15:R112 -
An evidence-based recommendation on bed head elevation for mechanically ventilated patients
A semi-upright position in ventilated patients is recommended to prevent ventilator-associated pneumonia (VAP) and is one of the components in the Ventilator Bundle of the Institute for Health Care Improvement...
Citation: Critical Care 2011 15:R111 -
Beyond volutrauma in ARDS: the critical role of lung tissue deformation
Ventilator-induced lung injury (VILI) consists of tissue damage and a biological response resulting from the application of inappropriate mechanical forces to the lung parenchyma. The current paradigm attribut...
Citation: Critical Care 2011 15:304 -
Out-of-hospital CPR: better outcome for our patients
Out-of-hospital cardiac arrest is a leading cause of death in developed countries and early resuscitation attempts are crucial to improve survival rates and neurological outcome. Gräsner and colleagues perform...
Citation: Critical Care 2011 15:149
Follow
- ISSN: 1364-8535 (electronic)