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  1. Authors: H Missaka, JE Almeida, PC Figueiredo, CL Nogueira, VR Julião, JLL Alencar, RS Lannes, SL Fernandes, G Caetani, J Abrantes, TD Bevilacqua, V Antonucci, PHCF Pinto and S Divan-Filho
    Citation: Critical Care 2011 15(Suppl 2):P48

    This article is part of a Supplement: Volume 15 Supplement 2

  2. Necrotizing fasciitis (NF) is a life threatening infectious disease with a high mortality rate. We carried out a microbiological characterization of the causative pathogens. We investigated the correlation of ...

    Authors: I-Chuan Chen, Wen-Cheng Li, Yu-Cheng Hong, Shian-Sen Shie, Wen-Chih Fann and Cheng-Ting Hsiao
    Citation: Critical Care 2011 15:R152
  3. Impact of gender on severe infections is in highly controversial discussion with natural survival advantage of females described in animal studies but contradictory to those described human data. This study ai...

    Authors: Irit Nachtigall, Sascha Tafelski, Andreas Rothbart, Lutz Kaufner, Maren Schmidt, Andrey Tamarkin, Maxim Kartachov, Daniela Zebedies, Tanja Trefzer, Klaus-Dieter Wernecke and Claudia Spies
    Citation: Critical Care 2011 15:R151
  4. Pseudomonas aeruginosa is a frequent cause of ventilator-acquired pneumonia (VAP). Candida tracheobronchial colonization is associated with higher rates of VAP related to P. aeruginosa. This study was designed to...

    Authors: Florence Ader, Samir Jawhara, Saad Nseir, Eric Kipnis, Karine Faure, Fanny Vuotto, Chanez Chemani, Boualem Sendid, Daniel Poulain and Benoit Guery
    Citation: Critical Care 2011 15:R150
  5. Sepsis is a complex immunological response to infection characterized by early hyper-inflammation followed by severe and protracted immunosuppression, suggesting that a multi-marker approach has the greatest c...

    Authors: Allison Sutherland, Mervyn Thomas, Roslyn A Brandon, Richard B Brandon, Jeffrey Lipman, Benjamin Tang, Anthony McLean, Ranald Pascoe, Gareth Price, Thu Nguyen, Glenn Stone and Deon Venter
    Citation: Critical Care 2011 15:R149
  6. Acute hemodynamic instability increases morbidity and mortality. We investigated whether early non-invasive cardiac output monitoring enhances hemodynamic stabilization and improves outcome.

    Authors: Jukka Takala, Esko Ruokonen, Jyrki J Tenhunen, Ilkka Parviainen and Stephan M Jakob
    Citation: Critical Care 2011 15:R148
  7. Acute kidney injury is common in intensive care patients and continuous renal replacement therapy is the preferred treatment for this in most centres. Although these techniques have been adopted internationall...

    Authors: Michael Joannidis and Lui G Forni
    Citation: Critical Care 2011 15:223
  8. The need for early, rapid, and substantial fluid resuscitation in septic patients has long been an article of faith in the intensive care community, a tribal totem that is taboo to question. The results of a r...

    Authors: Andrew K Hilton and Rinaldo Bellomo
    Citation: Critical Care 2011 15:164
  9. Recently, newer assays for cardiac troponin (cTn) have been developed which are able to detect changes in concentration of the biomarker at or below the 99th percentile for a normal population. The objective o...

    Authors: Yonathan Freund, Camille Chenevier-Gobeaux, Pascale Bonnet, Yann-Erick Claessens, Jean-Christophe Allo, Benoit Doumenc, François Leumani, Claudine Cosson, Bruno Riou and Patrick Ray
    Citation: Critical Care 2011 15:R147
  10. In adults, small (< 50%) serum creatinine (SCr) increases predict mortality. It is unclear whether different baseline serum creatinine (bSCr) estimation methods affect findings of acute kidney injury (AKI)-out...

    Authors: Omar Alkandari, K Allen Eddington, Ayaz Hyder, France Gauvin, Thierry Ducruet, Ronald Gottesman, Véronique Phan and Michael Zappitelli
    Citation: Critical Care 2011 15:R146
  11. The diagnostic and prognostic value of arterial blood gas analysis (ABGA) parameters in unselected patients presenting with acute dyspnea to the Emergency Department (ED) is largely unknown.

    Authors: Emanuel Burri, Mihael Potocki, Beatrice Drexler, Philipp Schuetz, Alexandre Mebazaa, Ulrike Ahlfeld, Catharina Balmelli, Corinna Heinisch, Markus Noveanu, Tobias Breidthardt, Nora Schaub, Tobias Reichlin and Christian Mueller
    Citation: Critical Care 2011 15:R145
  12. Enteral nutrition (EN) with eicosapentaenoic acid (EPA)/γ-linolenic acid (GLA) is recommended for mechanically ventilated patients with severe lung injury. EPA/GLA has anti-inflammatory benefits, as evidenced ...

    Authors: Alessandro Pontes-Arruda, Laércia Ferreira Martins, Samya Maria de Lima, Alexandre Marini Isola, Diogo Toledo, Ederlon Rezende, Marcelo Maia and Gisele Brocco Magnan
    Citation: Critical Care 2011 15:R144
  13. Significant physical sequelae exist for some survivors of a critical illness. There are, however, few studies that have examined specific interventions to improve their recovery, and none have tested a home-ba...

    Authors: Doug Elliott, Sharon McKinley, Jennifer Alison, Leanne M Aitken, Madeleine King, Gavin D Leslie, Patricia Kenny, Penny Taylor, Rachel Foley and Elizabeth Burmeister
    Citation: Critical Care 2011 15:R142
  14. Increasingly, derived estimates of glomerular filtration, such as the modification of diet in renal disease (MDRD) equation and Cockcroft-Gault (CG) formula are being employed in the intensive care unit (ICU)....

    Authors: João Pedro Baptista, Andrew A Udy, Eduardo Sousa, Jorge Pimentel, Lisa Wang, Jason A Roberts and Jeffrey Lipman
    Citation: Critical Care 2011 15:R139
  15. In recent years, fever control in critically ill patients by medications and/or external cooling has gained widespread use, notably in patients suffering from neurological injuries. Nevertheless, such a strate...

    Authors: Yoann Launey, Nicolas Nesseler, Yannick Mallédant and Philippe Seguin
    Citation: Critical Care 2011 15:222
  16. Heavy sedation in the ICU is associated with coma, delirium, and prolonged stays, but links between sedatives and non-brain organ failure have rarely been described. In a post hoc analysis, Strøm and colleagues e...

    Authors: Nathan E Brummel and Timothy D Girard
    Citation: Critical Care 2011 15:163
  17. Sepsis is responsible for important alterations in the pharmacokinetics of antibiotics. Continuous renal replacement therapy (CRRT), which is commonly used in septic patients, may further contribute to pharmac...

    Authors: Lucie Seyler, Frédéric Cotton, Fabio Silvio Taccone, Daniel De Backer, Pascale Macours, Jean-Louis Vincent and Frédérique Jacobs
    Citation: Critical Care 2011 15:R137
  18. The objective of this study was to determine the ability of various parameters commonly used for the diagnosis of acute meningitis to differentiate between bacterial and viral meningitis, in adult patients wit...

    Authors: Alain Viallon, Nicolas Desseigne, Olivier Marjollet, Albert Birynczyk, Mathieu Belin, Stephane Guyomarch, Jacques Borg, Bruno Pozetto, Jean Claude Bertrand and Fabrice Zeni
    Citation: Critical Care 2011 15:R136
  19. Because of disturbed renal autoregulation, patients experiencing hypotension-induced renal insult might need higher levels of mean arterial pressure (MAP) than the 65 mmHg recommended level in order to avoid t...

    Authors: Julie Badin, Thierry Boulain, Stephan Ehrmann, Marie Skarzynski, Anne Bretagnol, Jennifer Buret, Dalila Benzekri-Lefevre, Emmanuelle Mercier, Isabelle Runge, Denis Garot, Armelle Mathonnet, Pierre-François Dequin and Dominique Perrotin
    Citation: Critical Care 2011 15:R135
  20. Sepsis is the leading cause of acute kidney injury (AKI) in critical patients. The optimal timing of initiating renal replacement therapy (RRT) in septic AKI patients remains controversial. The objective of th...

    Authors: Yu-Hsiang Chou, Tao-Min Huang, Vin-Cent Wu, Cheng-Yi Wang, Chih-Chung Shiao, Chun-Fu Lai, Hung-Bin Tsai, Chia-Ter Chao, Guang-Huar Young, Wei-Jei Wang, Tze-Wah Kao, Shuei-Liong Lin, Yin-Yi Han, Anne Chou, Tzu-Hsin Lin, Ya-Wen Yang…
    Citation: Critical Care 2011 15:R134
  21. Tidal volume and plateau pressure minimisation are the standard components of a protective lung ventilation strategy for patients with acute respiratory distress syndrome (ARDS). Open lung strategies, includin...

    Authors: Carol L Hodgson, David V Tuxen, Andrew R Davies, Michael J Bailey, Alisa M Higgins, Anne E Holland, Jenny L Keating, David V Pilcher, Andrew J Westbrook, David J Cooper and Alistair D Nichol
    Citation: Critical Care 2011 15:R133
  22. The rapid institution of therapeutic hypothermia after cardiac arrest has become an accepted practice. In the previous issue of Critical Care, Haugk and colleagues present a retrospective analysis of 13 years of ...

    Authors: Daniel Howes and David W Messenger
    Citation: Critical Care 2011 15:162
  23. Total hip replacement is one of the most commonly performed major orthopaedic operations. Goal-directed therapy (GDT) using haemodynamic monitoring has previously demonstrated outcome benefits in high-risk sur...

    Authors: Maurizio Cecconi, Nicola Fasano, Nicola Langiano, Michele Divella, Maria G Costa, Andrew Rhodes and Giorgio Della Rocca
    Citation: Critical Care 2011 15:R132