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  3. In the ICU, peripherally inserted central catheters (PICCs) may be an alternative option to standard central venous catheters, particularly in patients with coagulation disorders or at high risk for infection....

    Authors: Mauro Pittiruti, Alberto Brutti, Davide Celentano, Massimiliano Pomponi, Daniele G Biasucci, Maria Giuseppina Annetta and Giancarlo Scoppettuolo
    Citation: Critical Care 2012 16:R21
    Content type: Research Published on:

  4. The Molecular Adsorbent Recycling System (MARS) is used to treat patients with liver failure. Observational data suggest that citrate anticoagulation during MARS is feasible. Comparative studies on the optimal...

    Authors: Björn Meijers, Wim Laleman, Pieter Vermeersch, Frederik Nevens, Alexander Wilmer and Pieter Evenepoel
    Citation: Critical Care 2012 16:R20
    Content type: Research Published on:

  5. Critical care patients frequently receive blood transfusions. Some reports show an association between aged or stored blood and increased morbidity and mortality, including the development of transfusion-relat...

    Authors: John-Paul Tung, John F Fraser, Maria Nataatmadja, Kathryn I Colebourne, Adrian G Barnett, Kristen M Glenister, Anna Y Zhou, Peter Wood, Christopher C Silliman and Yoke L Fung
    Citation: Critical Care 2012 16:R19
    Content type: Research Published on:

  8. The renal clearance of infused crystalloid fluid is very low during anaesthesia and surgery, but experiments in conscious sheep indicate that the renal fluid clearance might approach a normal rate when the adr...

    Authors: Yu Hong Li, Hai Bin Zhu, Xiaozhu Zheng, Han Jian Chen, Liang Shao and Robert G Hahn
    Citation: Critical Care 2012 16:R18
    Content type: Research Published on:

  11. Resuscitation of septic patients by means of one or more fluid boluses is recommended by guidelines from multiple relevant organizations and as a component of surviving sepsis campaigns. The technique is consi...

    Authors: Andrew K Hilton and Rinaldo Bellomo
    Citation: Critical Care 2012 16:302
    Content type: Viewpoint Published on:

  12. Acute kidney injury (AKI) after cardiac surgery increases length of hospital stay and in-hospital mortality. A significant number of patients undergoing cardiac surgical procedures require perioperative intra-...

    Authors: Martina Nowak-Machen, James D Rawn, Prem S Shekar, Aya Mitani, Sagun Tuli, Tobias M Bingold, Garrett Lawlor, Holger K Eltzschig, Stanton K Shernan and Peter Rosenberger
    Citation: Critical Care 2012 16:R17
    Content type: Research Published on:

  13. One of the therapeutic essentials in severe sepsis and septic shock is an adequate fluid replacement to restore and maintain circulating plasma volume, improve organ perfusion and nutritive microcirculatory fl...

    Authors: Tim Philipp Simon, Tobias Schuerholz, Lars Hüter, Michael Sasse, Florian Heyder, Wolfgang Pfister and Gernot Marx
    Citation: Critical Care 2012 16:R16
    Content type: Research Published on:

  14. We sought to determine the effect of nutritional support and insulin infusion therapy on serum and brain glucose levels and cerebral metabolic crisis after aneurysmal subarachnoid hemorrhage (SAH).

    Authors: J Michael Schmidt, Jan Claassen, Sang-Bae Ko, Hector Lantigua, Mary Presciutti, Kiwon Lee, E Sander Connolly, Stephan A Mayer, David S Seres and Neeraj Badjatia
    Citation: Critical Care 2012 16:R15
    Content type: Research Published on:

  16. To evaluate whether alkaline phosphatase (AP) treatment improves renal function in sepsis-induced acute kidney injury (AKI), a prospective, double-blind, randomized, placebo-controlled study in critically ill ...

    Authors: Peter Pickkers, Suzanne Heemskerk, Jeroen Schouten, Pierre-François Laterre, Jean-Louis Vincent, Albertus Beishuizen, Philippe G Jorens, Herbert Spapen, Michael Bulitta, Wilbert HM Peters and Johannes G van der Hoeven
    Citation: Critical Care 2012 16:R14
    Content type: Research Published on:

  18. Acute kidney injury (AKI) increases mortality and morbidity of critically ill patients. Mortality of patients treated with renal replacement therapy (RRT) is high. We aimed to evaluate the nationwide incidence...

    Authors: Suvi T Vaara, Ville Pettilä, Matti Reinikainen and Kirsi-Maija Kaukonen
    Citation: Critical Care 2012 16:R13
    Content type: Research Published on:

  19. Following trauma and systemic inflammatory response syndrome (SIRS), the typical response is an elevation of the total complete blood count (CBC) and a reduction of the lymphocyte count. This leukocytosis typi...

    Authors: Daithi S Heffernan, Sean F Monaghan, Rajan K Thakkar, Jason T Machan, William G Cioffi and Alfred Ayala
    Citation: Critical Care 2012 16:R12
    Content type: Research Published on:

  22. Although nonthyroidal illness syndrome is considered to be associated with adverse outcome in ICU patients, the performance of thyroid hormone levels in predicting clinical outcome in ICU patients is unimpress...

    Authors: Feilong Wang, Wenzhi Pan, Hairong Wang, Shuyun Wang, Shuming Pan and Junbo Ge
    Citation: Critical Care 2012 16:R11
    Content type: Research Published on:

  24. We recently found that platelet cytochrome c oxidase (COX) activities and quantities in 6-month-survival septic patients are significantly higher than those of patients who died before 6 months. Other studies ...

    Authors: Leonardo Lorente, Ruth Iceta, María M Martín, Esther López-Gallardo, Jordi Solé-Violán, José Blanquer, Lorenzo Labarta, César Díaz, Alejandro Jiménez, Julio Montoya and Eduardo Ruiz-Pesini
    Citation: Critical Care 2012 16:R10
    Content type: Research Published on:

  26. Inflammation may critically affect mechanisms of liver injury in acetaminophen (APAP) hepatotoxicity. Kupffer cells (KC) play important roles in inflammation, and KC depletion confers protection at early time ...

    Authors: Runkuan Yang, Xiaoping Zou, Marja-Leena Koskinen and Jyrki Tenhunen
    Citation: Critical Care 2012 16:R9
    Content type: Research Published on:

  27. Cyclic alveolar recruitment/derecruitment (R/D) is an important mechanism of ventilator-associated lung injury. In experimental models this process can be measured with high temporal resolution by detection of...

    Authors: Erik K Hartmann, Stefan Boehme, Alexander Bentley, Bastian Duenges, Klaus U Klein, Amelie Elsaesser, James E Baumgardner, Matthias David and Klaus Markstaller
    Citation: Critical Care 2012 16:R8
    Content type: Research Published on:

  31. Critical illness leads to increased endogenous production of carbon monoxide (CO) due to the induction of the stress-response enzyme, heme oxygenase-1 (HO-1). There is evidence for the cytoprotective and anti-...

    Authors: Andreas S Fazekas, Marlene Wewalka, Christian Zauner and Georg-Christian Funk
    Citation: Critical Care 2012 16:R6
    Content type: Research Published on:

  32. Copeptin is a peptide derived from pre-provasospression along with arginine vasospressin. In the setting of aneurysmal subarachnoid hemorrhage (SAH), elevated serum copeptin levels correlate with vasospasm, in...

    Authors: Rafael J Tamargo
    Citation: Critical Care 2012 16:103
    Content type: Commentary Published on:

  35. Despite their difficult definition and taxonomy, it is imperative to study critical incidents in intensive care, since they may be followed by adverse events and compromised patient safety. Identifying recurri...

    Authors: Panagiotis Kiekkas, Diamanto Aretha, Nikolaos Stefanopoulos and George I Baltopoulos
    Citation: Critical Care 2012 16:102
    Content type: Commentary Published on:

  37. Alcoholic patients comprise a large proportion of patients in intensive care units (ICUs). However, data are limited on the impact of alcoholism on mortality after intensive care.

    Authors: Steffen Christensen, Martin B Johansen, Lars Pedersen, Reinhold Jensen, Kim M Larsen, Anders Larsson, Else Tønnesen, Christian F Christiansen and Henrik T Sørensen
    Citation: Critical Care 2012 16:R5
    Content type: Research Published on:

  38. The benefits of higher positive end expiratory pressure (PEEP) in patients with acute respiratory distress syndrome (ARDS) have been modest, but few studies have fully tested the "open-lung hypothesis". This h...

    Authors: Gustavo FJ de Matos, Fabiana Stanzani, Rogerio H Passos, Mauricio F Fontana, Renata Albaladejo, Raquel E Caserta, Durval CB Santos, João Batista Borges, Marcelo BP Amato and Carmen SV Barbas
    Citation: Critical Care 2012 16:R4
    Content type: Research Published on:

  39. The use of low-dose steroid therapy in the management of septic shock has been extensively studied. However, the association between the timing of low-dose steroid therapy and the outcome has not been evaluate...

    Authors: Hye Yun Park, Gee Young Suh, Jae-Uk Song, Hongseok Yoo, Ik Joon Jo, Tae Gun Shin, So Yeon Lim, Sookyoung Woo and Kyeongman Jeon
    Citation: Critical Care 2012 16:R3
    Content type: Research Published on:

  40. The accurate prediction of acute kidney injury (AKI) in patients with acute heart failure (AHF) is an unmet clinical need. Neutrophil gelatinase-associated lipocalin (NGAL) is a novel sensitive and specific ma...

    Authors: Tobias Breidthardt, Thenral Socrates, Beatrice Drexler, Markus Noveanu, Corinna Heinisch, Nisha Arenja, Theresia Klima, Christina Züsli, Tobias Reichlin, Mihael Potocki, Raphael Twerenbold, Jürg Steiger and Christian Mueller
    Citation: Critical Care 2012 16:R2
    Content type: Research Published on:

  41. The diagnosis of acute lung injury (ALI) may be more robust if more accurate physiological markers can be identified. Extravascular lung water (EVLW) is one possible marker, and it has been shown to correlate ...

    Authors: Michelle S Chew, Lilian Ihrman, Joachim During, Lill Bergenzaun, Anders Ersson, Johan Undén, Jörgen Ryden, Eva Åkerman and Marina Larsson
    Citation: Critical Care 2012 16:R1
    Content type: Research Published on:

  42. Probiotics are live micro-organisms with a health promoting effect. Because of their immunomodulating capacity as well as improvement of gut barrier function, probiotics have the capacity to prevent infectious...

    Authors: Ger T Rijkers
    Citation: Critical Care 2011 15:1022
    Content type: Commentary Published on:

  44. Delirium occurs frequently in critically ill patients and is associated with disease severity and infection. Although several pathways for delirium have been described, biomarkers associated with delirium in i...

    Authors: Mark van den Boogaard, Matthijs Kox, Kieran L Quinn, Theo van Achterberg, Johannes G van der Hoeven, Lisette Schoonhoven and Peter Pickkers
    Citation: Critical Care 2011 15:R297
    Content type: Research Published on:

  46. Childbirth is a major event in the lives of mothers and their families. Critical illness in pregnancy is uncommon but may arise from conditions unique to pregnancy, conditions exacerbated by pregnancy and coin...

    Authors: Felicity Plaat and Monica Naik
    Citation: Critical Care 2011 15:1014
    Content type: Commentary Published on:

  48. Fluid strategies may impact on patient outcomes in major elective surgery. We aimed to study the effectiveness and cost-effectiveness of pre-operative fluid loading in high-risk surgical patients undergoing ma...

    Authors: Brian H Cuthbertson, Marion K Campbell, Stephen A Stott, Andrew Elders, Rodolfo Hernández, Dwayne Boyers, John Norrie, John Kinsella, Julie Brittenden, Jonathan Cook, Daniela Rae, Seonaidh C Cotton, David Alcorn, Jennifer Addison and Adrian Grant
    Citation: Critical Care 2011 15:R296
    Content type: Research Published on:
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  • ISSN: 1364-8535 (electronic)

Critical Care

ISSN: 1364-8535