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  1. Chlorhexidine-gluconate (CHG) impregnated dressings may prevent catheter-related bloodstream infections (CRBSI). Chlorhexidine-impregnated sponge dressings (sponge-dress) and gel dressings (gel-dress) have nev...

    Authors: Niccolò Buetti, Stéphane Ruckly, Carole Schwebel, Olivier Mimoz, Bertrand Souweine, Jean-Christophe Lucet and Jean-François Timsit
    Citation: Critical Care 2020 24:458
    Content type: Research Published on:

    The Letter to this article has been published in Critical Care 2020 24:563

  5. Nebulised unfractionated heparin (UFH) has a strong scientific and biological rationale and warrants urgent investigation of its therapeutic potential, for COVID-19-induced acute respiratory distress syndrome ...

    Authors: Frank M. P. van Haren, Clive Page, John G. Laffey, Antonio Artigas, Marta Camprubi-Rimblas, Quentin Nunes, Roger Smith, Janis Shute, Mary Carroll, Julia Tree, Miles Carroll, Dave Singh, Tom Wilkinson and Barry Dixon
    Citation: Critical Care 2020 24:454
    Content type: Review Published on:

  6. Hypoxia is common during daily nursing procedures (DNPs) routinely performed on mechanically ventilated patients. The impact of automated ventilation on the incidence and severity of blood oxygen desaturation ...

    Authors: Jonathan Chelly, Sandie Mazerand, Sebastien Jochmans, Claire-Marie Weyer, Franck Pourcine, Olivier Ellrodt, Nathalie Thieulot-Rolin, Jean Serbource-Goguel, Oumar Sy, Ly Van Phach Vong and Mehran Monchi
    Citation: Critical Care 2020 24:453
    Content type: Research Published on:

  12. Five to 10% of the coronavirus SARS-CoV-2-infected patients, i.e., with new coronavirus disease 2019 (COVID-19), are presenting with an acute respiratory distress syndrome (ARDS) requiring urgent respiratory a...

    Authors: Ronan Thibault, Philippe Seguin, Fabienne Tamion, Claude Pichard and Pierre Singer
    Citation: Critical Care 2020 24:447
    Content type: Review Published on:

  14. COVID-19 is an emerging disease that can manifest itself as asymptomatic or mild respiratory tract infection in the majority of individuals, but in some, it can progress into severe pneumonia and acute respira...

    Authors: Frank L. van de Veerdonk and Mihai G. Netea
    Citation: Critical Care 2020 24:445
    Content type: Review Published on:

  17. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has been increasingly used over the last decade in patients with refractory cardiogenic shock. ECMO weaning can, however, be challenging and lead to ...

    Authors: Enrique Guilherme, Matthias Jacquet-Lagrèze, Matteo Pozzi, Felix Achana, Xavier Armoiry and Jean-Luc Fellahi
    Citation: Critical Care 2020 24:442
    Content type: Research Published on:

    The Correction to this article has been published in Critical Care 2020 24:487

  18. Septic shock is associated with decreased vasopressor responsiveness. Experimental data suggest that central alpha2-agonists like dexmedetomidine (DEX) increase vasopressor responsiveness and reduce catecholam...

    Authors: Luca Cioccari, Nora Luethi, Michael Bailey, Yahya Shehabi, Belinda Howe, Anna S. Messmer, Helena K. Proimos, Leah Peck, Helen Young, Glenn M. Eastwood, Tobias M. Merz, Jukka Takala, Stephan M. Jakob and Rinaldo Bellomo
    Citation: Critical Care 2020 24:441
    Content type: Research Published on:

    The Letter to this article has been published in Critical Care 2021 25:56

  21. Coronavirus disease 2019 (COVID-19) has become a public health emergency of global concern. We aimed to explore the risk factors of 14-day and 28-day mortality and develop a model for predicting 14-day and 28-...

    Authors: Shuai Zhang, Mengfei Guo, Limin Duan, Feng Wu, Guorong Hu, Zhihui Wang, Qi Huang, Tingting Liao, Juanjuan Xu, Yanling Ma, Zhilei Lv, Wenjing Xiao, Zilin Zhao, Xueyun Tan, Daquan Meng, Shujing Zhang…
    Citation: Critical Care 2020 24:438
    Content type: Research Published on:

  25. Improving timeliness of pathogen identification is crucial to allow early adaptation of antibiotic therapy and improve prognosis in patients with pneumonia. We evaluated the relevance of a new syndromic rapid ...

    Authors: Céline Monard, Jonathan Pehlivan, Gabriel Auger, Sophie Alviset, Alexy Tran Dinh, Paul Duquaire, Nabil Gastli, Camille d’Humières, Adel Maamar, André Boibieux, Marion Baldeyrou, Julien Loubinoux, Olivier Dauwalder, Vincent Cattoir, Laurence Armand-Lefèvre and Solen Kernéis
    Citation: Critical Care 2020 24:434
    Content type: Research Published on:

  26. Measurement of central venous pressure (CVP) can be a useful clinical tool. However, the formal utility of CVP measurement in preventing mortality in septic patients has never been proven.

    Authors: Hui Chen, Zhu Zhu, Chenyan Zhao, Yanxia Guo, Dongyu Chen, Yao Wei and Jun Jin
    Citation: Critical Care 2020 24:433
    Content type: Research Published on:

  27. Endotracheal suctioning (ES) provokes a cumulative hemodynamic response by activation of sympathetic and parasympathetic circuits in the central nervous system. In this proof-of-concept study, we aimed to anal...

    Authors: Verena Rass, Bogdan-Andrei Ianosi, Anna Lindner, Mario Kofler, Alois J. Schiefecker, Bettina Pfausler, Ronny Beer, Erich Schmutzhard and Raimund Helbok
    Citation: Critical Care 2020 24:432
    Content type: Research Published on:

  33. Clostridioides difficile infection (CDI) is a leading cause of nosocomial diarrhea. Patients receiving enteral nutrition (EN) in the intensive care unit (ICU) are potentially at high risk of CDI. In the present s...

    Authors: Daosheng Wang, Danfeng Dong, Chen Wang, Yingchao Cui, Cen Jiang, Qi Ni, Tongxuan Su, Guanzheng Wang, Enqiang Mao and Yibing Peng
    Citation: Critical Care 2020 24:426
    Content type: Research Published on:

  36. Dysregulation of the host immune response is a pathognomonic feature of sepsis. Abnormal physiological conditions are understood to shift efficient linear splicing of protein-coding RNA towards non-canonical s...

    Authors: Hina N. Khan, Xanthe Brands, Simona Aufiero, Arie J. Hoogendijk, Augustijn M. Klarenbeek, Tjitske S. R. van Engelen, Bastiaan W. Haak, Lonneke A. van Vught, Janneke Horn, Marcus J. Schultz, Aeilko H. Zwinderman, Tom van der Poll and Brendon P. Scicluna
    Citation: Critical Care 2020 24:423
    Content type: Research Published on:

  37. An outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that started in Wuhan, China, at the end of 2019 has become a global pandemic. Both SARS-CoV-2 and SARS-CoV enter...

    Authors: Wentao Ni, Xiuwen Yang, Deqing Yang, Jing Bao, Ran Li, Yongjiu Xiao, Chang Hou, Haibin Wang, Jie Liu, Donghong Yang, Yu Xu, Zhaolong Cao and Zhancheng Gao
    Citation: Critical Care 2020 24:422
    Content type: Review Published on:

  38. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the global spread of coronavirus disease (COVID-19). Our understanding of the impact this virus has on the nervous system is limi...

    Authors: Gaurav Nepal, Jessica Holly Rehrig, Gentle Sunder Shrestha, Yow Ka Shing, Jayant Kumar Yadav, Rajeev Ojha, Gaurab Pokhrel, Zhi Lan Tu and Dong Ya Huang
    Citation: Critical Care 2020 24:421
    Content type: Research Published on:

  41. The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak is spreading worldwide. To date, no specific treatment has convincingly demonstrated its efficacy. Hydroxychloroquine and lopinavir/rit...

    Authors: Marie Lecronier, Alexandra Beurton, Sonia Burrel, Luc Haudebourg, Robin Deleris, Julien Le Marec, Sara Virolle, Safaa Nemlaghi, Côme Bureau, Pierre Mora, Martin De Sarcus, Olivier Clovet, Baptiste Duceau, Paul Henri Grisot, Marie Hélène Pari, Jérémy Arzoine…
    Citation: Critical Care 2020 24:418
    Content type: Research Published on:

  42. Mechanical power (MP) is the energy delivered to the respiratory system over time during mechanical ventilation. Our aim was to compare the currently available methods to calculate MP during volume- and pressu...

    Authors: Davide Chiumello, Miriam Gotti, Mariateresa Guanziroli, Paolo Formenti, Michele Umbrello, Iacopo Pasticci, Giovanni Mistraletti and Mattia Busana
    Citation: Critical Care 2020 24:417
    Content type: Research Published on:

  43. Cystatin C is a well-validated marker of glomerular filtration rate in chronic kidney disease. Higher plasma concentrations of cystatin C are associated with worse clinical outcomes in heterogenous populations...

    Authors: Carolyn M. Hendrickson, Yuenting D. Kwong, Annika G. Belzer, Michael G. Shlipak, Michael A. Matthay and Kathleen D. Liu
    Citation: Critical Care 2020 24:416
    Content type: Research Published on:
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  • ISSN: 1364-8535 (electronic)

Critical Care

ISSN: 1364-8535