Fig. 2
From: Pneumocystis jirovecii pneumonia in intensive care units: a multicenter study by ESGCIP and EFISG
PPV and NPV for presumptive/proven PJP of serum BDG and respiratory Pneumocystis PCR both separately and in combination. BDG, (1,3)-β-D-glucan; NPV, negative predictive value; PCR, polymerase chain reaction; PJP, Pneumocystis jirovecii pneumonia; PPV, positive predictive value. Criteria for positivity used for the comparisons in the graph are manufactures’ cut-offs for BDG (80 pg/mL for the Fungitell assay and 11 pg/mL for the Wako assay) and any positive result for respiratory Pneumocystis PCR (see study methods). For the combination (PCR plus BDG), the reported PPV was obtained when both markers were concordant in indicating PJP (both positive), while the reported NPV was obtained when both markers when concordant in indicating no PJP (both negative)