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Table 1 Overview of respondent’s input based on the survey

From: International survey on influenza-associated pulmonary aspergillosis (IAPA) in intensive care units: responses suggest low awareness and potential underdiagnosis outside Europe

 

Responses

Total

Europe

U.S.

Othera

Valid respondents

565 (100%)

208 (37%)

224 (40%)

133 (23%)

Role at ICU

 Critical care physician

509/565 (90%)

197/208 (95%)

186/224 (83%)

126/133 (95%)

 Infectious diseases physician

8/565 (1%)

4/208 (2%)

3/224 (1%)

1/133 (0.5%)

 Nurse

9/565 (2%)

1/208 (1%)

7/224 (3%)

1/133 (0.5%)

 Other

39/565 (7%)

6/208 (2%)

28/224 (13%)

5/133 (4%)

Number of ICU beds

 < 20 beds

176/554 (32%)

94/207 (46%)

27/222 (12%)

55/125 (44%)

 21–60 beds

226/554 (41%)

85/207 (41%)

89/222 (40%)

52/125 (42%)

 61–100 beds

68/554 (12%)

17/207 (8%)

43/222 (19%)

8/125 (6%)

 > 100 beds

84/554 (15%)

11/207 (5%)

63/222 (29%)

10/125 (8%)

Number of severe influenza cases per season

 < 10 cases

132/557 (23%)

56/206 (27%)

32/222 (14%)

44/129 (34%)

 11–30 cases

272/557 (49%)

118/206 (57%)

99/222 (45%)

55/129 (43%)

 31–50 cases

60/557 (11%)

18/206 (9%)

30/222 (14%)

12/129 (9%)

 >  50 cases

49/557 (9%)

10/206 (5%)

27/222 (12%)

12/129 (9%)

 I do not know

44/557 (8%)

4/206 (2%)

34/222 (15%)

6/129 (5%)

NAIs as standardized treatment

 Yes

416/556 (75%)

162/206 (79%)

165/222 (74%)

89/128 (70%)

 Yes, but only if influenza symptoms started ≤ 48–72 h before ICU admission

97/556 (17%)

34/206 (17%)

41/222 (19%)

22/128 (17%)

 No

27/556 (5%)

7/206 (3%)

3/222 (1%)

17/128 (13%)

 I do not know

16/556 (3%)

3/206 (1%)

13/222 (6%)

0

Obtaining lower respiratory samples

 Always

78/554 (14%)

52/205 (25%)

10/220 (5%)

16/129 (12%)

 Very often

139/554 (25%)

67/205 (33%)

43/220 (19%)

29/129 (22%)

 Sometimes

187/554 (34%)

50/205 (24%)

97/220 (44%)

40/129 (31%)

 Rarely

129/554 (23%)

31/205 (15%)

65/220 (29%)

33/129 (26%)

 Never

16/554 (3%)

5/205 (3%)

1/220 (1%)

10/129 (8%)

 N/A—have not treated patients

5/554 (1%)

0

4/220 (2%)

1/129 (1%)

Galactomannan testing in BAL

 Always

52/551 (9%)

38/204 (19%)

5/220 (2%)

9/127 (7%)

 Very often

65/551 (12%)

38/204 (19%)

14/220 (6%)

13/127 (10%)

 Sometimes

107/551 (19%)

37/204 (18%)

46/220 (21%)

24/127 (19%)

 Rarely

163/551 (30%)

43/204 (21%)

83/220 (38%)

37/127 (29%)

 Never

143/551 (26%)

44/204 (21%)

61/220 (28%)

38/127 (30%)

 N/A—have not treated patients

21/551 (4%)

4/204 (2%)

11/220 (5%)

6/127 (5%)

Galactomannan testing in serum

 Always

39/554 (7%)

28/205 (14%)

5/220 (2%)

6/129 (5%)

 Very often

60/554 (11%)

36/205 (18%)

11/220 (5%)

13/129 (10%)

 Sometimes

115/554 (21%)

42/205 (20%)

46/220 (21%)

27/129 (21%)

 Rarely

175/554 (31%)

47/205 (23%)

94/220 (43%)

34/129 (26%)

 Never

142/554 (26%)

48/205 (23%)

51/220 (23%)

43/129 (33%)

 N/A—have not treated patients

23/554 (4%)

4/205 (2%)

13/220 (6%)

6/129 (5%)

Number of IAPA in influenza patients in the past 5 years

 No

347/553 (63%)

85/204 (41%)

183/220 (83%)

79/129 (61%)

 Yes, 1 patient

77/553 (14%)

34/204 (17%)

21/220 (9%)

22/129 (17%)

 Yes, 2–5 patients

99/553 (18%)

61/204 (30%)

15/220 (7%)

23/129 (18%)

 Yes, > 5 patients

30/553 (5%)

24/204 (12%)

1/220 (1%)

5/129 (4%)

  1. Descriptive statistics were used to analyze the differences in proportions of responses between Europe, the US, and other countries. Fisher’s exact or χ2 test was used to calculate the p values. Correction for multiple comparisons was applied. The Spearman rank-order correlation coefficient was used to determine univariate correlations between parameters. A p value of < 0.05 was considered statistically significant. Results were analyzed using SPSS (IBM SPSS Statistics version 26). ICU intensive care unit, N/A not applicable, BAL bronchoalveolar lavage, IAPA influenza-associated pulmonary aspergillosis
  2. aOther countries + unknown