Table 2 Clinical course and cardiac parameters before and during the first 48 h of support with Impella 5.0

Alive, number (%)

40 (100 %)

40 (100 %)

39 (98 %)

38 (95 %)

37 (93 %)

MAP, mmHg

65 [58–74]

76 [66–86]^a

76 [71–80]^a

79 [74–88]^a

80 [75–86]^a

Impella flow, L/min

-

3.5 [2.6–3.9]

3.8 [2.4–4.3]

3.7 [2.5–4.2]

3.9 [3.3–4.2]^b

ECMO flow, L/min

4.1 [2.5–4.3]

3.9 [3.3–4.7]

3.6 [3.5–4.2]

3.6 [3.1–4.1]^b

3.2 [2.5–3.9]^b

PaO2/FiO2 ratio

204 [160–311]

188 [121–280]

203 [132–324]

245 [187–327]

244 [172–335]

ScvO2^*, %

62 [56–68]

74 [68–77]

70 [65–77]

75 [70–80]

70 [69–73]

Blood lactate (mmol/L)

3.8 [1.7–5.9]^**

3.4 [1.7–5.1]

2.5 [1.5–3.4]^a,b

1.6 [1.2–2.8]^a,b

1.5 [1.0–2.1]^a,b

SOFA score

12 [9.8–14.0]^**

9.0 [7.0–11.0]^a

-

8.5 [7.0–11.0]^a,b

8.0 [5.0–10.0]^a,b

Vasoactive-inotropic score

51 [13–112]

47 [17–96]

43 [18–82]

24 [8–56]^a,b

9 [0–32]^a,b

Inotrope score

10 [1–17]

5 [0–15]

1 [0–9]^a,b

0 [0–4]^a,b

0 [0–0.4]^a,b

Cardiothoracic ratio

0.58 [0.52–0.66]

-

-

0.55 [0.50–0.60]^a

0.54 [0.49–0.59]^a

NT-proBNP (ng/L)

3736 [1436–8024]

-

-

1638 [799–5689]^a

1780 [745–3931]^a