- Poster presentation
- Open Access
Incidence, risk factors, and impact on mortality of status epilepticus in sepsis in the United States
© Urtecho et al. 2011
- Published: 1 March 2011
- Status Epilepticus
- Hospital Mortality
- Septic Patient
- Clinical Modification
- Metabolic Dysfunction
We sought to determine the epidemiology of status epilepticus (SE), prevalence of risk factors and impact on hospital mortality in sepsis in the United States. We hypothesized that SE would be associated with increased mortality.
Data were derived from the National Inpatient Sample from 1998 to 2008. We included patients older than 18 years, with a primary diagnosis of sepsis and SE. Definitions were based on the International Classification of Diseases, Ninth Revision, Clinical Modification Codes (ICD-9). Adjusted incidence rates, prevalence odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. Multivariate logistical models assessed for the impact of SE on hospital mortality.
Our study demonstrates the incidence of SE in sepsis is increasing. Despite a decline in sepsis-related mortality, the presence of SE doubles the risk of in-hospital death. Further study is needed to determine whether detection and treatment of SE will impact mortality.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.