- Poster presentation
- Open Access
Demographic and outcome differences in ICU patients with proven invasive candidiasis, possible invasive candidiasis and probable candida colonization: analysis of the EPIC II study population
- Published: 1 March 2011
Keywords
- Adult Patient
- Emergency Medicine
- Bacterial Infection
- Hospital Discharge
- Outcome Data
Introduction
To evaluate differences in ICU patients with proven invasive candidiasis (Proven-IC), possible invasive candidiasis (Possible-IC), probable Candida colonization (colonized), and non-infected, noncolonized (non-infected) patients.
Methods
EPIC II recruited 1,265 ICUs in 76 countries. Patient characteristics were collected on the study day. Outcome data were assessed at ICU and hospital discharge. Patients infected or colonized with non-Candida pathogens were excluded from this analysis. Patients with positive candida cultures may have had concurrent bacterial infections or colonization (*P < 0.05 compared with the non-infected group). Numerical values are reported as mean ± SD and length of stay (LOS) data as median (IQ).
Results
(abstract P238
Proven-IC | Possible-IC | Colonized | Non-infected | |
|---|---|---|---|---|
( n = 110) | ( n = 278) | ( n = 371) | ( n = 6,509) | |
SAPS II mean (SD)* | 58 (14) | 41 (15) | 40 (16) | 31 (14) |
Mechanical ventilation (n, %)* | 77 (71%) | 204 (73%) | 255 (70%) | 2,822 (44%) |
Vaspressors (n, %)* | 37 (34%) | 87 (31%) | 129 (35%) | 1,251 (19%) |
ICU mortality (n, %)* | 45 (42%) | 93 (34%) | 102 (29%) | 649 (11%) |
ICU LOS median (IQ)* | 33 (18,52) | 30 (16,52) | 23 (11,41) | 4 (1,4) |
Conclusions
ICU patients with proven invasive candidiasis, possible invasive candidiasis and candida colonization were more acutely ill and undergoing more ICU interventions than non-infected patients. The ICU mortality and LOS were also greater.
Authors’ Affiliations
References
- Vincent JL, et al.: JAMA. 2009, 302: 2323-2329. 10.1001/jama.2009.1754View ArticlePubMedGoogle Scholar
Copyright
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
