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End-tidal carbon dioxide levels predict cardiac arrest
Critical Care volume 15, Article number: P80 (2011)
End-tidal carbon dioxide (CO2) correlates with cardiac output during cardiopulmonary resuscitation (CPR) in cardiac arrest patients. Increasing CO2 during CPR can also indicate the return of spontaneous circulation.
CO2 was continuously monitored and recorded every 4 hours in 43 patients who were intubated and on vasopressor medications.
Mean CO2 values were significantly higher in normal patients when compared with those in patients who had a cardiac arrest (30.18 ± 4.93 vs. 17.45 ± 4.76; P < 0.001). CO2 levels were significantly lower in cardiac arrest patients when compared with hypotensive patients 1, 2, 3, and 4 hours prior to a cardiac arrest (see Table 1). CO2 levels were significantly lower in cardiac arrest patients when compared with patients who were acutely withdrawn from care 1, 2, 3, and 4 hours prior to the event (see Table 2).
CO2 levels decrease prior to cardiac arrest and are signi-ficantly lower than prior to hypotensive or acute withdrawal of care events. Further study needs to be done on a larger scale to see whether these results hold true.
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Manyam, H., Thiagarajah, P., Patel, G. et al. End-tidal carbon dioxide levels predict cardiac arrest. Crit Care 15, P80 (2011). https://doi.org/10.1186/cc9500
- Public Health
- Carbon Dioxide
- Cardiac Output
- Emergency Medicine