- Poster presentation
- Open Access
Fluid resuscitation based on dynamic predictors of fluid responsiveness: closed loop algorithm versus anesthesiologists
© Rinehart et al. 2011
- Published: 1 March 2011
- Cardiac Output
- Mean Arterial Pressure
- Fluid Resuscitation
- Fluid Responsiveness
- Simulated Patient
Closed-loop management of fluid resuscitation has historically been difficult. Given the dynamic predictors of fluid responsiveness, automated management is now feasible. We present simulation data for a novel patient-adaptive closed-loop fluid management algorithm using pulse pressure variation (PPV) as the input variable.
Using a simulator that includes physiologic PPV output, 20 practicing anesthesiology residents and faculty were asked to manage fluids and pressors for a 1-hour simulated hemorrhage case of 2 l blood loss over 20 minutes (group 1). One week later, they repeated the simulation, but this time fluids were secretly managed by the closed-loop system while practitioner fluid administrations were ignored and only the pressors were entered (group 2). The simulation was also run 20 times with only the closed-loop (group 3) and 20 times with no management (group 4).
Our data demonstrate that closed-loop management of fluid resuscitation is feasible using our novel dynamic-parameter based algorithm and that this approach can be used to optimize cardiac output.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.