Skip to main content
  • Poster presentation
  • Open access
  • Published:

Metabolic syndrome and coronary artery bypass graft surgery


Metabolic syndrome (MS) is a constellation of disorders that increases the risk for coronary heart disease. This study was conducted to examine the incidence of metabolic syndrome in coronary artery bypass graft (CABG) patients and to determine if metabolic syndrome affects clinical outcomes in the perioperative setting.


A cohort study of elective CABG surgery patients. Metabolic syndrome was defined using recent established criteria [1]. Demographic variables, comorbid conditions, surgical procedures and postoperative variables were collected. SPSS 15 was used.


We studied 508 patients. MS was defined in 333 (66%) patients, 241 (72%) males and 92 (28%) females, mean age 66 ± 9 years. MS had greater glucose levels at all postoperative time points (F: 41.6, P < 0.001), higher leptins levels (F: 4.7, P < 0.044), higher thrombomodulin at 0 hours and 4 hours after surgery (F: 6, P = 0.016), and lower 24-hour-postoperative blood loss after adjusting by tranexamic acid (F: 4.6, P = 0.032). MS had higher incidence of renal dysfunction (RIFLE: I) 13 (4%) versus 1 (0.6%) (P = 0.027).


MS was associated with a procoagulant state that may decrease postoperative blood loss. Nevertheless MS was associated with worse adverse events as renal dysfunction.


  1. Alberti RH, et al.: Circulation. 2009, 120: 1640-1645. 10.1161/CIRCULATIONAHA.109.192644

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and permissions

About this article

Cite this article

Brouard, M., Jimenez, J., Iribarren, J. et al. Metabolic syndrome and coronary artery bypass graft surgery. Crit Care 15 (Suppl 1), P5 (2011).

Download citation

  • Published:

  • DOI: