Skip to main content


You are viewing the new article page. Let us know what you think. Return to old version

Meeting abstract | Open | Published:

Optimisation of high risk surgical patients improves mortality in clinical practice


Deliberately increasing oxygen delivery (DO2) in the peri-operative period has been shown to improve survival for high risk surgical patients, in several randomised, controlled, trails [1].

Design, subjects and methods

A prospective study evaluating the efficacy of increasing peri-operative oxygen delivery in high risk surgical patients, to greater than 600 ml/min/m2 with dopexamine hydrochloride, in routine clinical practice


Expressed as medians with 25%, 75% centiles.


An 11.9% 28 day mortality rate compares favourably with historical controls and clinical trials. This study confirms that the technique of increasing DO2 in the peri-operative period is both practical and beneficial in routine clinical practice.

Table 1 Table


  1. 1.

    Boyd O, Grounds RM, Bennett ED: . JAMA. 1993, 270: 2699-2707. 10.1001/jama.270.22.2699.

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article


  • Oxygen
  • Public Health
  • Clinical Trial
  • High Risk
  • Mortality Rate