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- Open Access
Optimisation of high risk surgical patients improves mortality in clinical practice
Critical Care volume 1, Article number: P097 (1997)
Deliberately increasing oxygen delivery (DO2) in the peri-operative period has been shown to improve survival for high risk surgical patients, in several randomised, controlled, trails .
Design, subjects and methods
A prospective study evaluating the efficacy of increasing peri-operative oxygen delivery in high risk surgical patients, to greater than 600 ml/min/m2 with dopexamine hydrochloride, in routine clinical practice
Expressed as medians with 25%, 75% centiles.
An 11.9% 28 day mortality rate compares favourably with historical controls and clinical trials. This study confirms that the technique of increasing DO2 in the peri-operative period is both practical and beneficial in routine clinical practice.
Boyd O, Grounds RM, Bennett ED: . JAMA. 1993, 270: 2699-2707. 10.1001/jama.270.22.2699.
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Rhodes, A., Lamb, F., Newman, P. et al. Optimisation of high risk surgical patients improves mortality in clinical practice. Crit Care 1, P097 (1997). https://doi.org/10.1186/cc81
- Public Health
- Clinical Trial
- High Risk
- Mortality Rate