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Table 3 Comparing the first and the fourth hemodynamic measurements in patients with sepsis and acute heart failure

From: Transpulmonary thermodilution-derived cardiac function index identifies cardiac dysfunction in acute heart failure and septic patients: an observational study

  Sepsis Acute heart failure
  1st measurement 4th measurement 1st measurement 4th measurement
  n = 9 n = 9 n = 12 n = 12
Basic monitoring     
   Heart rate, 1/minute 83 (80–96) 90 (78–108) 87 (72–97) 85 (75–95)
   MAP, mm Hg 75 (65–81) 77 (69–86) 74 (70–78) 66 (58–75)a, b
   RAP, mm Hg 13 (9.0–17) 12 (10–15) 13 (9.5–15) 11 (8.3–15)
   SaO2, percentage 94 (91–96) 94 (93–97) 95 (94–96) 94 (93–97)
PAC     
   CI, L/minute per m2 3.8 (3.1–4.3) 4.8 (3.7–6.2) 2.6 (1.9–3.1)a 2.8 (2.3–3.1)a
   CP, W 1.00 (0.88–1.32) 1.33 (1.04–1.87) 0.71 (0.59–0.95) 0.80 (0.65–0.93)a
   LVSWI, g-m/m2 32 (23–45) 42 (34–54)b 20 (17–25)a, c 18 (17–29)a, c
   MPAP, mm Hg 31 (30–32) 27 (27–31) 32 (27–37) 31 (22–35)
   PAOP, mm Hg 18 (15–21) 17 (14–18) 21 (17–26)c 19 (12–20)b, c
   SmvO2, percentage 68 (61–74) 70 (60–75) 50 (48–62)a, d 59 (52–64)a, b, d
PiCCO     
   CI, L/minute per m2 3.6 (3.5–5.6) 4.8 (3.8–5.4) 2.9 (1.8–3.8)a 2.9 (2.2–3.3)a
   CFI, 1/minute 6.0 (3.3–6.8) 6.4 (3.5–8.0) 2.7 (2.2–2.9)a 2.7 (2.4–3.6)a
   GEF, percentage 21 (15–30) 25 (16–34) 13 (9.8–14)a 14 (12–17)a
   GEDVI, mL/m2 857 (703–1,128) 797 (660–1,164) 1,141 (893–1,311)a 904 (796–1,144)b
   ELWI, mL/kg 18.2 (14.7–24.0) 15.3 (12.4–20.2) 15.4 (13.7–22.4) 15.7 (14.0–19.2)
   PVPI 2.6 (2.2–4.1) 3.0 (1.9–3.4) 2.8 (2.0–3.8) 2.5 (1.9–2.8)
   ELWI/GEDVI, × 102 2.0 (1.6–2.7) 2.1 (1.4–2.3) 1.6 (1.2–2.4) 1.9 (1.4–2.2)
  1. The results are presented as medians (interquartile ranges). aP < 0.05 between the two groups for a given time point; bP < 0.05 for changes between the two time points within a group. Reduced numbers because of missing data are indicated by superscript c (c), where n = 10, and superscript d (d), where n = 11. CFI: cardiac function index; CI: cardiac index; CP: cardiac power; ELWI: extravascular lung water index; GEDVI: global end-diastolic volume index; GEF: global ejection fraction; LVSWI: left ventricular stroke work index; MAP: mean arterial pressure; MPAP: mean pulmonary arterial pressure; PAC: pulmonary artery catheter; PAOP: pulmonary artery occlusion pressure; PiCCO: transpulmonary thermodilution technique; PVPI: pulmonary vascular permeability index; RAP: right atrial pressure; SaO2: arterial oxygen saturation; SmvO2: mixed venous oxygen saturation.