| |
Sepsis
|
Acute heart failure
|
|---|
| |
1st measurement
|
4th measurement
|
1st measurement
|
4th measurement
|
|---|
| |
n = 9
|
n = 9
|
n = 12
|
n = 12
|
|
Basic monitoring
| | | | |
|
Heart rate, 1/minute
|
83 (80–96)
|
90 (78–108)
|
87 (72–97)
|
85 (75–95)
|
|
MAP, mm Hg
|
75 (65–81)
|
77 (69–86)
|
74 (70–78)
|
66 (58–75)a, b
|
|
RAP, mm Hg
|
13 (9.0–17)
|
12 (10–15)
|
13 (9.5–15)
|
11 (8.3–15)
|
|
SaO2, percentage
|
94 (91–96)
|
94 (93–97)
|
95 (94–96)
|
94 (93–97)
|
|
PAC
| | | | |
|
CI, L/minute per m2
|
3.8 (3.1–4.3)
|
4.8 (3.7–6.2)
|
2.6 (1.9–3.1)a
|
2.8 (2.3–3.1)a
|
|
CP, W
|
1.00 (0.88–1.32)
|
1.33 (1.04–1.87)
|
0.71 (0.59–0.95)
|
0.80 (0.65–0.93)a
|
|
LVSWI, g-m/m2
|
32 (23–45)
|
42 (34–54)b
|
20 (17–25)a, c
|
18 (17–29)a, c
|
|
MPAP, mm Hg
|
31 (30–32)
|
27 (27–31)
|
32 (27–37)
|
31 (22–35)
|
|
PAOP, mm Hg
|
18 (15–21)
|
17 (14–18)
|
21 (17–26)c
|
19 (12–20)b, c
|
|
SmvO2, percentage
|
68 (61–74)
|
70 (60–75)
|
50 (48–62)a, d
|
59 (52–64)a, b, d
|
|
PiCCO
| | | | |
|
CI, L/minute per m2
|
3.6 (3.5–5.6)
|
4.8 (3.8–5.4)
|
2.9 (1.8–3.8)a
|
2.9 (2.2–3.3)a
|
|
CFI, 1/minute
|
6.0 (3.3–6.8)
|
6.4 (3.5–8.0)
|
2.7 (2.2–2.9)a
|
2.7 (2.4–3.6)a
|
|
GEF, percentage
|
21 (15–30)
|
25 (16–34)
|
13 (9.8–14)a
|
14 (12–17)a
|
|
GEDVI, mL/m2
|
857 (703–1,128)
|
797 (660–1,164)
|
1,141 (893–1,311)a
|
904 (796–1,144)b
|
|
ELWI, mL/kg
|
18.2 (14.7–24.0)
|
15.3 (12.4–20.2)
|
15.4 (13.7–22.4)
|
15.7 (14.0–19.2)
|
|
PVPI
|
2.6 (2.2–4.1)
|
3.0 (1.9–3.4)
|
2.8 (2.0–3.8)
|
2.5 (1.9–2.8)
|
|
ELWI/GEDVI, × 102
|
2.0 (1.6–2.7)
|
2.1 (1.4–2.3)
|
1.6 (1.2–2.4)
|
1.9 (1.4–2.2)
|
- The results are presented as medians (interquartile ranges). aP < 0.05 between the two groups for a given time point; bP < 0.05 for changes between the two time points within a group. Reduced numbers because of missing data are indicated by superscript c (c), where n = 10, and superscript d (d), where n = 11. CFI: cardiac function index; CI: cardiac index; CP: cardiac power; ELWI: extravascular lung water index; GEDVI: global end-diastolic volume index; GEF: global ejection fraction; LVSWI: left ventricular stroke work index; MAP: mean arterial pressure; MPAP: mean pulmonary arterial pressure; PAC: pulmonary artery catheter; PAOP: pulmonary artery occlusion pressure; PiCCO: transpulmonary thermodilution technique; PVPI: pulmonary vascular permeability index; RAP: right atrial pressure; SaO2: arterial oxygen saturation; SmvO2: mixed venous oxygen saturation.
