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Table 3 Comparing the first and the fourth hemodynamic measurements in patients with sepsis and acute heart failure

From: Transpulmonary thermodilution-derived cardiac function index identifies cardiac dysfunction in acute heart failure and septic patients: an observational study

 

Sepsis

Acute heart failure

 

1st measurement

4th measurement

1st measurement

4th measurement

 

n = 9

n = 9

n = 12

n = 12

Basic monitoring

    

   Heart rate, 1/minute

83 (80–96)

90 (78–108)

87 (72–97)

85 (75–95)

   MAP, mm Hg

75 (65–81)

77 (69–86)

74 (70–78)

66 (58–75)a, b

   RAP, mm Hg

13 (9.0–17)

12 (10–15)

13 (9.5–15)

11 (8.3–15)

   SaO2, percentage

94 (91–96)

94 (93–97)

95 (94–96)

94 (93–97)

PAC

    

   CI, L/minute per m2

3.8 (3.1–4.3)

4.8 (3.7–6.2)

2.6 (1.9–3.1)a

2.8 (2.3–3.1)a

   CP, W

1.00 (0.88–1.32)

1.33 (1.04–1.87)

0.71 (0.59–0.95)

0.80 (0.65–0.93)a

   LVSWI, g-m/m2

32 (23–45)

42 (34–54)b

20 (17–25)a, c

18 (17–29)a, c

   MPAP, mm Hg

31 (30–32)

27 (27–31)

32 (27–37)

31 (22–35)

   PAOP, mm Hg

18 (15–21)

17 (14–18)

21 (17–26)c

19 (12–20)b, c

   SmvO2, percentage

68 (61–74)

70 (60–75)

50 (48–62)a, d

59 (52–64)a, b, d

PiCCO

    

   CI, L/minute per m2

3.6 (3.5–5.6)

4.8 (3.8–5.4)

2.9 (1.8–3.8)a

2.9 (2.2–3.3)a

   CFI, 1/minute

6.0 (3.3–6.8)

6.4 (3.5–8.0)

2.7 (2.2–2.9)a

2.7 (2.4–3.6)a

   GEF, percentage

21 (15–30)

25 (16–34)

13 (9.8–14)a

14 (12–17)a

   GEDVI, mL/m2

857 (703–1,128)

797 (660–1,164)

1,141 (893–1,311)a

904 (796–1,144)b

   ELWI, mL/kg

18.2 (14.7–24.0)

15.3 (12.4–20.2)

15.4 (13.7–22.4)

15.7 (14.0–19.2)

   PVPI

2.6 (2.2–4.1)

3.0 (1.9–3.4)

2.8 (2.0–3.8)

2.5 (1.9–2.8)

   ELWI/GEDVI, × 102

2.0 (1.6–2.7)

2.1 (1.4–2.3)

1.6 (1.2–2.4)

1.9 (1.4–2.2)

  1. The results are presented as medians (interquartile ranges). aP < 0.05 between the two groups for a given time point; bP < 0.05 for changes between the two time points within a group. Reduced numbers because of missing data are indicated by superscript c (c), where n = 10, and superscript d (d), where n = 11. CFI: cardiac function index; CI: cardiac index; CP: cardiac power; ELWI: extravascular lung water index; GEDVI: global end-diastolic volume index; GEF: global ejection fraction; LVSWI: left ventricular stroke work index; MAP: mean arterial pressure; MPAP: mean pulmonary arterial pressure; PAC: pulmonary artery catheter; PAOP: pulmonary artery occlusion pressure; PiCCO: transpulmonary thermodilution technique; PVPI: pulmonary vascular permeability index; RAP: right atrial pressure; SaO2: arterial oxygen saturation; SmvO2: mixed venous oxygen saturation.