Procalcitonin: a prognostic marker for critically ill
© Bhattacharyya and Todi; licensee BioMed Central Ltd. 2009
Published: 13 March 2009
Procalcitonin (PCT) is a marker of sepsis and the levels correlate with the severity of illness.
A prospective, observational study conducted in the medical surgical intensive therapy unit of a tertiary-care centre in India. Three hundred critically ill adult patients with suspected sepsis during any time of the intensive therapy unit stay in whom PCT was estimated were included in the study. PCT was assessed by quantitative immunoluminometric assay. The demographics of the study population, and APACHE II and APACHE IV scores were recorded.
Comparison between APACHE II, APACHE IV and PCT
Area under the curve
Positive predictive value
Negative predictive value
PCT is a reliable marker for prognostication with a high negative predictive value and comparable with APACHE prediction models.
This article is published under license to BioMed Central Ltd.