- Poster presentation
- Open Access
Alterations of the immune system in acute pancreatitis and systematic inflammatory response syndrome
Critical Care volume 13, Article number: P147 (2009)
A considerable body of evidence indicates the contribution of the immune system to the mechanisms leading to acute pancreatitis . Data focusing on the early course of events at the clinical ground of the process are lacking. The aim of the present study was to provide a complex evaluation of peripheral blood monocyte and subpopulations of lymphocytes in patients with acute pancreatitis and systemic inflammatory response syndrome.
Forty-three patients were enrolled in the study; 33 with acute pancreatitis and systemic inflammatory response syndrome, and 10 healthy subjects. Peripheral blood immune cells were studied on days 1 and 4 by flow cytometry.
Results indicate an early and significant response of NK cells and of CD4 apoptosis in the initial events of acute pancreatitis.
Dabrowski A, et al.: Monocyte subsets and natural killer cells in acute pancreatitis. Pancreatology 2008, 8: 126-134. 10.1159/000123605
About this article
Cite this article
Mylona, V., Vaki, I., Lymberopoulou, K. et al. Alterations of the immune system in acute pancreatitis and systematic inflammatory response syndrome. Crit Care 13, P147 (2009). https://doi.org/10.1186/cc7311
- Immune System
- Flow Cytometry
- Natural Killer
- Immune Cell