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Table 2 Comparison of comorbidities of the patients in studies by Rivers and colleagues [2] and Sprung and colleagues (CORTICUS) [23]

From: Bench-to-bedside review: The initial hemodynamic resuscitation of the septic patient according to Surviving Sepsis Campaign guidelines – does one size fit all?

  Rivers et al. Sprung et al.  
  (n = 263) (n = 499) Chi-square test
Caucasian (%) Not reported 93  
Age (years) 65.7 63  
Male/Female (%) 50.6/49.4 66.5/33.5 0.0000
Hypertension (%) 67.3 37.7a 0.0000
Coronary artery disease (%) 25.0 16.9a 0.0080
Congestive heart failure (%) 33.4 6.0a 0.0000
Diabetes (%) 31.4 21.6a 0.0030
Chronic obstructive pulmonary disease (%) 15.7 11.3a 0.0900
Chronic renal failure (%) 21.7 8.7a 0.0000
Liver disease (%) 23.3 8.1a 0.0000
Neurologic disease (%) 33.0 11.7a 0.0000
Cancer (%) 11.4 16.9a 0.0580
Alcohol use (%) 38.6 Not reported  
  1. an = 496. CORTICUS, Corticosteroid Therapy of Septic Shock.