- Poster presentation
- Open Access
Determination of SpO2/FiO2 thresholds to impute for PaO2/FiO2 ratios in the Sequential Organ Failure Assessment score
© BioMed Central Ltd 2008
- Published: 13 March 2008
- Respiratory Distress Syndrome
- Linear Regression Model
- Distress Syndrome
- Organ Dysfunction
- Acute Respiratory Distress Syndrome
The Sequential Organ Failure Assessment (SOFA) score is a well-validated and effective method by which to measure organ dysfunction in critically ill patients and is a good indicator of prognosis. However, repeated arterial blood gas data are often lacking for calculating the respiratory component of the SOFA score on a daily basis. The aim of this study was to derive SpO2/FiO2 (S/F) ratio correlations with the PaO2/FiO2 (P/F) ratio in assessing the respiratory parameters of the SOFA score, incorporating the level of positive end-expiratory pressure (PEEP).
Matched measurements of SpO2 (limited to values ≤ 98%) and PaO2 from patients admitted with acute respiratory distress syndrome were used to determine the relationship between S/F and P/F, using three separate linear regression models, for patients on <8 cmH2O PEEP, 8–12 cmH2O PEEP and >12 cmH2O PEEP. S/F threshold values correlating with P/F ratios of 100, 200, 300 and 400 were determined, using the equation derived from the model.
PEEP < 8 cmH2O
PEEP 8 - 12 cmH2O
PEEP > 12 cmH2O
S/F ratios categorized by the level of PEEP can be used to impute for P/F ratios in the calculation of the respiratory component of the SOFA score.
This article is published under license to BioMed Central Ltd.