- Poster presentation
- Open Access
Surrogate markers of pulmonary edema and severity of lung injury do not accurately reflect measured extravascular lung water
© BioMed Central Ltd 2008
- Published: 13 March 2008
- Linear Regression Analysis
- Lung Injury
- Clinical Parameter
- Pulmonary Edema
Determination of extravascular lung water (EVLW) by transpulmonary thermodilution predicts progression to acute lung injury (ALI). Early identification of patients at risk for developing ALI may impact clinical decision-making. Measurement of EVLW, however, is invasive, requiring central venous and arterial catheters. We asked whether less invasive clinical parameters and markers of severity of lung injury could be used to estimate lung water, obviating the need for the more invasive determination.
Poor correlation of EVLW with the PaO2/FiO2 ratio (r2 = 0.0061), CVP (r2 = 0.1261), fluid balance (r2 = 0.0903), Vd/Vt (r2 = 0.0135), Cs (r2 = 0.0014), and LIS (r2 = 0.0837) was seen (Figure 1).
The clinical parameters examined in this study do not accurately reflect the EVLW and should not be used as surrogates for it.
This article is published under license to BioMed Central Ltd.