Transfusion policy and outcome in critically ill patients with a long ICU stay
© BioMed Central Ltd 2008
Published: 13 March 2008
Patients with a long ICU stay (>7 days) are prone to develop anemia due to high severity of disease, repeated flebotomies and inflammatory status with altered erythropoiesis. They are also more prone to receive a blood transfusion. The aim of our study was to assess the hemoglobin (Hb) transfusion trigger and the influence of blood transfusion on outcome in critically ill patients with an ICU length of stay (LOS) >7 days.
The prospective noninterventional study was performed in a mixed 19-bed ICU of a tertiary care university hospital and included all patients with an ICU LOS > 7 days admitted during 1 year. Patients were divided into two groups: patients never transfused (NT group), and patients ever transfused (ET group). Collected data were demographic data, severity scores, Hb transfusion trigger, transfusion data, ICU LOS and outcome. Statistical analysis was conducted using the Student t test and multinomial logistic regression.
Patients, n (%)
Worst APACHE score
23.2 ± 9.5
22.2 ± 9.8
Worst SOFA score
8.9 ± 3.6
9.8 ± 4.4
The incidence of anemia in critically ill patients with a long ICU stay is high (83% at ICU admission, 95% at ICU discharge). The transfusion trigger Hb was 7.8 g%, a value that matches the actual restrictive policy. Blood transfusion was an independent risk factor for increased mortality in the ET group.
This article is published under license to BioMed Central Ltd.