APACHE II and SOFA scores for intensive care and hospital outcome prediction in oncologic patients
© BioMed Central Ltd 2007
Published: 19 June 2007
The number of acute organ failures has been shown to be an important determinant of prognosis in critically ill cancer patients admitted to an ICU . Although the SOFA score is useful in analyzing the number and the severity of acute organ failures related to ICU mortality, it is not validated to predict outcomes in the ICU. On the other hand, general prognostic models have failed to accurately predict outcomes in the oncologic population [2, 3]. Given this, we propose to analyze the ability of the SOFA score compared with the APACHE II score in predicting ICU and inhospital mortality in oncologic patients.
ICU data from a tertiary university hospital were prospectively collected from March 2003 to November 2005. Oncologic patients with an ICU admission longer than 24 hours were selected. The SOFA and APACHE II scores were retrieved from our prospectively acquired database. The accuracy of the APACHE II, first-day SOFA (SOFA1) and maximum SOFA during the entire ICU admission (mSOFA) scores were analyzed through the area under the ROC curve (AUC).
95% confidence interval
95% confidence interval
The accuracy of the APACHE II score to predict ICU and inhospital mortality in critically ill cancer patients was modest and similar to the described in the literature. The severity of multiple organ failure evaluated through the SOFA score on day 1 and the maximum SOFA score reached a better accuracy to predict both ICU and hospital mortality in an oncologic population.
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