A novel score based on age and cardiac biomarkers predicts outcomes in severe sepsis and septic shock
© BioMed Central Ltd. 2007
Published: 22 March 2007
Myocardial dysfunction is common among critically ill septic patients. Elevated levels of cardiac biomarkers are predictors of mortality in acute coronary syndrome and in unselected critically ill patients. Our aim was to evaluate the role of the cardiac markers NT-proBNP, Troponin T (TnT) and myoglobin as predictors of inhospital and 6-month all-cause mortality in patients admitted to a general adult ICU with severe sepsis/septic shock.
Serial plasma samples were taken for five sequential days on all patients admitted with severe sepsis/septic shock. Samples were analysed for NT-proBNP, TnT and myoglobin.
In critically ill patients with severe sepsis/septic shock a score based on age and increased plasma levels of cardiac biomarkers can help risk-stratify patients and predict short-term (<6 months) outcome.