- Poster presentation
- Open Access
Vasopressin, epinephrine, and methylprednisolone in inhospital cardiac arrest
© BioMed Central Ltd. 2007
- Published: 22 March 2007
- Public Health
- Group Patient
- Single Dose
Combined vasopressin, epinephrine, and methylprednisolone during cardiopulmonary resuscitation (CPR) may improve survival in inhospital cardiac arrest.
Ninety-one adults with cardiac arrest were randomized to receive either vasopressin (20 IU/CPR cycle for five cycles) plus epinephrine (1 mg/CPR cycle) plus methylprednisolone (single dose = 40 mg) or placebo plus epinephrine (1 mg/CPR cycle) plus placebo. Primary endpoints were return of spontaneous circulation (ROSC) for ≥15 minutes, and survival to discharge either to home or to a rehabilitation facility.
Combination treatment improves survival in inhospital cardiac arrest.